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Protein
Submitted name:

Disks large homolog 1

Gene

Dlg1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Disks large homolog 1Imported
Gene namesi
Name:Dlg1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 16

Organism-specific databases

MGIiMGI:107231 Dlg1

PTM / Processingi

Proteomic databases

MaxQBiD3Z3B8
PeptideAtlasiD3Z3B8
PRIDEiD3Z3B8

PTM databases

iPTMnetiD3Z3B8

Expressioni

Gene expression databases

BgeeiENSMUSG00000022770
ExpressionAtlasiD3Z3B8 baseline and differential
GenevisibleiD3Z3B8 MM

Structurei

3D structure databases

ProteinModelPortaliD3Z3B8
SMRiD3Z3B8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini141 – 228PDZInterPro annotationAdd BLAST88
Domaini236 – 323PDZInterPro annotationAdd BLAST88
Domaini383 – 464PDZInterPro annotationAdd BLAST82
Domaini498 – 568SH3InterPro annotationAdd BLAST71
Domaini644 – 819Guanylate kinase-likeInterPro annotationAdd BLAST176

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili773 – 793Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the MAGUK family.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, SH3 domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118866
HOGENOMiHOG000232102
OMAiNPKCIDH

Family and domain databases

InterProiView protein in InterPro
IPR016313 DLG1-like
IPR019590 DLG1_PEST_dom
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR020590 Guanylate_kinase_CS
IPR027417 P-loop_NTPase
IPR001478 PDZ
IPR019583 PDZ_assoc
IPR036034 PDZ_sf
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
PF10608 MAGUK_N_PEST, 1 hit
PF00595 PDZ, 3 hits
PF10600 PDZ_assoc, 1 hit
PF00018 SH3_1, 1 hit
PIRSFiPIRSF001741 MAGUK_DLGH, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SM01277 MAGUK_N_PEST, 1 hit
SM00228 PDZ, 3 hits
SM00326 SH3, 1 hit
SUPFAMiSSF50044 SSF50044, 2 hits
SSF50156 SSF50156, 3 hits
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00856 GUANYLATE_KINASE_1, 1 hit
PS50052 GUANYLATE_KINASE_2, 1 hit
PS50106 PDZ, 3 hits
PS50002 SH3, 1 hit

Sequencei

Sequence statusi: Complete.

D3Z3B8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNYIFGNNTL LYSRASRGGN ASSSHGSVGP KQKHWAKKGS SDELQAEPEP
60 70 80 90 100
SRWQQIVAFF TRRHSFIDCI SVATSSTQPT EAVPPSSPIV PVTPALPVPA
110 120 130 140 150
ESTVVLPSAP QANPPPVLVN TDSLETPTYV NGTDADYEYE EITLERGNSG
160 170 180 190 200
LGFSIAGGTD NPHIGDDSSI FITKIITGGA AAQDGRLRVN DCILRVNEAD
210 220 230 240 250
VRDVTHSKAV EALKEAGSIV RLYVKRRKPA SEKIMEIKLI KGPKGLGFSI
260 270 280 290 300
AGGVGNQHIP GDNSIYVTKI IEGGAAHKDG KLQIGDKLLA VNSVCLEEVT
310 320 330 340 350
HEEAVTALKN TSDFVYLKVA KPTSMYINDG YAPPDITNSS SQSVDNHVSP
360 370 380 390 400
SSCLGQTPTS PARYSPISKA VLGDDEITRE PRKVVLHRGS TGLGFNIVGG
410 420 430 440 450
EDGEGIFISF ILAGGPADLS GELRKGDRII SVNSVDLRAA SHEQAAAALK
460 470 480 490 500
NAGQAVTIVA QYRPEEYSRF EAKIHDLREQ MMNSSVSSGS GSLRTSQKRS
510 520 530 540 550
LYVRALFDYD KTKDSGLPSQ GLNFRFGDIL HVINASDDEW WQARQVTPDG
560 570 580 590 600
ESDEVGVIPS KRRVEKKERA RLKTVKFNSK TRGDKGEIPD DMGSKGLKHV
610 620 630 640 650
TSNASDSESS YLILITDEYG CSKGGQEEYV LSYEPVNQQE VNYTRPVIIL
660 670 680 690 700
GPMKDRVNDD LISEFPDKFG SCVPHTTRPK RDYEVDGRDY HFVTSREQME
710 720 730 740 750
KDIQEHKFIE AGQYNNHLYG TSVQSVRAVA EKGKHCILDV SGNAIKRLQI
760 770 780 790 800
AQLYPISIFI KPKSMENIME MNKRLTEEQA RKTFERAMKL EQEFTEHFTA
810 820 830
IVQGDTLEDI YNQVKQIIEE QSGPYIWVPA KEKL
Length:834
Mass (Da):91,623
Last modified:April 20, 2010 - v1
Checksum:i553E1EAF25E9FEC0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC126055 Genomic DNA No translation available.
AC129214 Genomic DNA No translation available.
RefSeqiNP_001239365.1, NM_001252436.1
UniGeneiMm.382

Genome annotation databases

EnsembliENSMUST00000115196; ENSMUSP00000110850; ENSMUSG00000022770
GeneIDi13383
UCSCiuc007yxt.2 mouse

Similar proteinsi

Entry informationi

Entry nameiD3Z3B8_MOUSE
AccessioniPrimary (citable) accession number: D3Z3B8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: March 28, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported