Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

D3Z314

- D3Z314_MOUSE

UniProt

D3Z314 - D3Z314_MOUSE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Natural resistance-associated macrophage protein 2

Gene

Slc11a2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. cadmium ion binding Source: Ensembl
  2. cadmium ion transmembrane transporter activity Source: Ensembl
  3. cobalt ion binding Source: Ensembl
  4. cobalt ion transmembrane transporter activity Source: MGI
  5. copper ion binding Source: Ensembl
  6. copper ion transmembrane transporter activity Source: Ensembl
  7. ferrous iron transmembrane transporter activity Source: MGI
  8. hydrogen ion transmembrane transporter activity Source: MGI
  9. iron ion binding Source: Ensembl
  10. iron ion transmembrane transporter activity Source: MGI
  11. lead ion transmembrane transporter activity Source: Ensembl
  12. manganese ion binding Source: Ensembl
  13. manganese ion transmembrane transporter activity Source: Ensembl
  14. nickel cation binding Source: Ensembl
  15. nickel cation transmembrane transporter activity Source: Ensembl
  16. solute:proton symporter activity Source: Ensembl
  17. vanadium ion transmembrane transporter activity Source: Ensembl
  18. zinc ion binding Source: Ensembl
  19. zinc ion transmembrane transporter activity Source: Ensembl

GO - Biological processi

  1. activation of cysteine-type endopeptidase activity involved in apoptotic process Source: Ensembl
  2. cellular response to hypoxia Source: Ensembl
  3. cellular response to iron ion Source: Ensembl
  4. cellular response to oxidative stress Source: Ensembl
  5. cellular response to tumor necrosis factor Source: Ensembl
  6. cobalt ion transport Source: MGI
  7. dendrite morphogenesis Source: MGI
  8. detection of oxygen Source: Ensembl
  9. erythrocyte development Source: MGI
  10. ferrous iron import Source: MGI
  11. ferrous iron transport Source: MGI
  12. heme biosynthetic process Source: MGI
  13. hydrogen ion transmembrane transport Source: GOC
  14. iron ion transport Source: MGI
  15. learning or memory Source: MGI
  16. multicellular organismal iron ion homeostasis Source: MGI
  17. porphyrin-containing compound biosynthetic process Source: MGI
  18. porphyrin-containing compound metabolic process Source: MGI
  19. proton transport Source: MGI
  20. response to cadmium ion Source: Ensembl
  21. response to lead ion Source: Ensembl
  22. response to manganese ion Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Natural resistance-associated macrophage protein 2Imported
Gene namesi
Name:Slc11a2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 15

Organism-specific databases

MGIiMGI:1345279. Slc11a2.

Subcellular locationi

GO - Cellular componenti

  1. apical plasma membrane Source: Ensembl
  2. basal part of cell Source: Ensembl
  3. brush border Source: MGI
  4. cell surface Source: MGI
  5. cytoplasmic vesicle Source: Ensembl
  6. early endosome Source: MGI
  7. endomembrane system Source: MGI
  8. endosome Source: MGI
  9. integral component of plasma membrane Source: MGI
  10. late endosome membrane Source: Ensembl
  11. lysosomal membrane Source: Ensembl
  12. nucleus Source: Ensembl
  13. paraferritin complex Source: Ensembl
  14. perinuclear region of cytoplasm Source: Ensembl
  15. plasma membrane Source: MGI
  16. recycling endosome Source: MGI
  17. trans-Golgi network Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiD3Z314.
ExpressionAtlasiD3Z314. baseline and differential.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000006526.
HOGENOMiHOG000152203.

Family and domain databases

InterProiIPR001046. NRAMP_fam.
[Graphical view]
PANTHERiPTHR11706. PTHR11706. 1 hit.
PfamiPF01566. Nramp. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

D3Z314 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVLDPKEKMP DDGASGDHGD SASLGAINPA YSNSSLPHST GDSEEPFTTY
60 70 80 90 100
FDEKIPIPEE EYSCFSFRKL WAFTGPGFLM SIAYLDPGNI ESDLQSGAVA
110 120 130 140 150
GFKLLWVLLL ATIVGLLLQR LAARLGVVTG LHLAEVCHRQ YPKVPRIILW
160 170
LMVELAIIGS DMQEVIGSAI
Length:170
Mass (Da):18,480
Last modified:April 20, 2010 - v1
Checksum:i94F283415217A7DD
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei170 – 1701Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC139571 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000123461; ENSMUSP00000119056; ENSMUSG00000023030.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC139571 Genomic DNA. No translation available.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000123461 ; ENSMUSP00000119056 ; ENSMUSG00000023030 .

Organism-specific databases

MGIi MGI:1345279. Slc11a2.

Phylogenomic databases

GeneTreei ENSGT00390000006526.
HOGENOMi HOG000152203.

Miscellaneous databases

ChiTaRSi SLC11A2. mouse.
NextBioi 35550665.
SOURCEi Search...

Gene expression databases

Bgeei D3Z314.
ExpressionAtlasi D3Z314. baseline and differential.

Family and domain databases

InterProi IPR001046. NRAMP_fam.
[Graphical view ]
PANTHERi PTHR11706. PTHR11706. 1 hit.
Pfami PF01566. Nramp. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiD3Z314_MOUSE
AccessioniPrimary (citable) accession number: D3Z314
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: October 29, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3