D3Z314 (D3Z314_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Natural resistance-associated macrophage protein 2 Ensembl ENSMUSP00000119056

Gene names

Name:

Slc11a2 Ensembl ENSMUSP00000119056 MGI 1345279

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000119056

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	170 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000119056

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process Inferred from electronic annotation. Source: Compara cadmium ion transmembrane transport Inferred from electronic annotation. Source: Compara cellular response to oxidative stress Inferred from electronic annotation. Source: Compara copper ion transport Inferred from electronic annotation. Source: Compara dendrite morphogenesis Inferred from mutant phenotype PubMed 19211831. Source: MGI detection of oxygen Inferred from electronic annotation. Source: Compara erythrocyte development Inferred from mutant phenotype PubMed 15849611. Source: MGI ferrous iron import Inferred from direct assay PubMed 15024413. Source: MGI heme biosynthetic process Inferred from mutant phenotype PubMed 11739192. Source: MGI lead ion transport Inferred from electronic annotation. Source: Compara learning or memory Inferred from mutant phenotype PubMed 19211831. Source: MGI manganese ion transmembrane transport Inferred from electronic annotation. Source: Compara multicellular organismal iron ion homeostasis Inferred from mutant phenotype PubMed 18076961PubMed 5070129. Source: MGI nickel cation transmembrane transport Inferred from electronic annotation. Source: Compara response to hypoxia Inferred from electronic annotation. Source: Compara
Cellular_component	apical plasma membrane Inferred from electronic annotation. Source: Compara basal part of cell Inferred from electronic annotation. Source: Compara brush border Inferred from direct assay PubMed 11090085. Source: MGI cell surface Inferred from direct assay PubMed 17097837. Source: MGI cytoplasmic vesicle Inferred from electronic annotation. Source: Compara early endosome Inferred from direct assay PubMed 12724326. Source: MGI endomembrane system Inferred from direct assay PubMed 12724326. Source: MGI integral to plasma membrane Inferred from direct assay PubMed 10942769. Source: MGI late endosome Inferred from electronic annotation. Source: Compara lysosome Inferred from electronic annotation. Source: Compara nucleus Inferred from electronic annotation. Source: Compara paraferritin complex Inferred from electronic annotation. Source: Compara perinuclear region of cytoplasm Inferred from electronic annotation. Source: Compara recycling endosome Inferred from direct assay PubMed 11739192PubMed 16905747. Source: MGI trans-Golgi network Inferred from electronic annotation. Source: Compara
Molecular_function	cobalt ion transmembrane transporter activity Inferred from direct assay PubMed 10942769PubMed 12522007PubMed 12724326PubMed 16142913PubMed 16905747. Source: MGI ferrous iron transmembrane transporter activity Inferred from direct assay PubMed 10942769PubMed 12522007PubMed 15024413. Source: MGI hydrogen ion transmembrane transporter activity Inferred from direct assay PubMed 15024413. Source: MGI solute:hydrogen symporter activity Inferred from electronic annotation. Source: Compara vanadium ion transmembrane transporter activity Inferred from electronic annotation. Source: Compara zinc ion transmembrane transporter activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	170	1	Ensembl ENSMUSP00000119056

Sequences

	Sequence		Length	Mass (Da)
	D3Z314 [UniParc]. Last modified April 20, 2010. Version 1. Checksum: 94F283415217A7DD	FASTA	170	18,480
	10 20 30 40 50 60 MVLDPKEKMP DDGASGDHGD SASLGAINPA YSNSSLPHST GDSEEPFTTY FDEKIPIPEE 70 80 90 100 110 120 EYSCFSFRKL WAFTGPGFLM SIAYLDPGNI ESDLQSGAVA GFKLLWVLLL ATIVGLLLQR 130 140 150 160 170 LAARLGVVTG LHLAEVCHRQ YPKVPRIILW LMVELAIIGS DMQEVIGSAI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000119056.
[2]	Ensembl Submitted (MAY-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000119056.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC139571 Genomic DNA. No translation available.
IPI	IPI00919229.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000123461; ENSMUSP00000119056; ENSMUSG00000023030.
Organism-specific databases
MGI	MGI:1345279. Slc11a2.
Phylogenomic databases
GeneTree	ENSGT00390000006526.
HOGENOM	HOG000152203.
Gene expression databases
ArrayExpress	D3Z314.
Bgee	D3Z314.
Family and domain databases
InterPro	IPR001046. Nat-R-assoc-macro_Nramp. [Graphical view]
PANTHER	PTHR11706. PTHR11706. 1 hit.
Pfam	PF01566. Nramp. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	SLC11A2. mouse.
NextBio	35550665.
SOURCE	Search...

Entry information

Entry name

D3Z314_MOUSE

Accession

Primary (citable) accession number: D3Z314

Entry history

Integrated into UniProtKB/TrEMBL:	April 20, 2010
Last sequence update:	April 20, 2010
Last modified:	April 3, 2013
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)