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D3Z2Z7

- D3Z2Z7_MOUSE

UniProt

D3Z2Z7 - D3Z2Z7_MOUSE

Protein
Submitted name:

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

Gene

Pik3cb

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. 1-phosphatidylinositol-3-kinase activity Source: MGI
    2. 1-phosphatidylinositol-4-phosphate 3-kinase activity Source: RefGenome
    3. insulin receptor substrate binding Source: MGI
    4. phosphatidylinositol-4,5-bisphosphate 3-kinase activity Source: RefGenome

    GO - Biological processi

    1. cellular calcium ion homeostasis Source: MGI
    2. embryonic cleavage Source: MGI
    3. homophilic cell adhesion Source: MGI
    4. phosphatidylinositol-3-phosphate biosynthetic process Source: GOC
    5. phosphatidylinositol-mediated signaling Source: InterPro
    6. platelet activation Source: MGI
    7. regulation of cell-matrix adhesion Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformImported
    Gene namesi
    Name:Pik3cbImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 9

    Organism-specific databases

    MGIiMGI:1922019. Pik3cb.

    Subcellular locationi

    GO - Cellular componenti

    1. phosphatidylinositol 3-kinase complex Source: RefGenome
    2. plasma membrane Source: RefGenome

    PTM / Processingi

    Proteomic databases

    PRIDEiD3Z2Z7.

    Expressioni

    Gene expression databases

    ArrayExpressiD3Z2Z7.
    BgeeiD3Z2Z7.

    Structurei

    3D structure databases

    ProteinModelPortaliD3Z2Z7.
    SMRiD3Z2Z7. Positions 13-68.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00620000087742.

    Family and domain databases

    InterProiIPR003113. PI3K_adapt-bd_dom.
    IPR015433. PI_Kinase.
    [Graphical view]
    PANTHERiPTHR10048. PTHR10048. 1 hit.
    PfamiPF02192. PI3K_p85B. 1 hit.
    [Graphical view]
    PROSITEiPS51544. PI3K_ABD. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    D3Z2Z7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPPAMADNLD IWAVDSQIAS DGAISVDFLL PTGIYIQLEV PREATISYIK   50
    QMLWKQVHNY PMFNLLMD 68
    Length:68
    Mass (Da):7,741
    Last modified:April 20, 2010 - v1
    Checksum:i90E5B4E63EAE2664
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei68 – 681Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC120148 Genomic DNA. No translation available.
    AC122930 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000124723; ENSMUSP00000121466; ENSMUSG00000032462.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC120148 Genomic DNA. No translation available.
    AC122930 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali D3Z2Z7.
    SMRi D3Z2Z7. Positions 13-68.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi D3Z2Z7.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000124723 ; ENSMUSP00000121466 ; ENSMUSG00000032462 .

    Organism-specific databases

    MGIi MGI:1922019. Pik3cb.

    Phylogenomic databases

    GeneTreei ENSGT00620000087742.

    Miscellaneous databases

    NextBioi 35550656.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi D3Z2Z7.
    Bgeei D3Z2Z7.

    Family and domain databases

    InterProi IPR003113. PI3K_adapt-bd_dom.
    IPR015433. PI_Kinase.
    [Graphical view ]
    PANTHERi PTHR10048. PTHR10048. 1 hit.
    Pfami PF02192. PI3K_p85B. 1 hit.
    [Graphical view ]
    PROSITEi PS51544. PI3K_ABD. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiD3Z2Z7_MOUSE
    AccessioniPrimary (citable) accession number: D3Z2Z7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 20, 2010
    Last sequence update: April 20, 2010
    Last modified: October 1, 2014
    This is version 34 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3