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D3Z2Z7

- D3Z2Z7_MOUSE

UniProt

D3Z2Z7 - D3Z2Z7_MOUSE

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Protein
Submitted name:

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

Gene

Pik3cb

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. 1-phosphatidylinositol-3-kinase activity Source: MGI
  2. 1-phosphatidylinositol-4-phosphate 3-kinase activity Source: RefGenome
  3. insulin receptor substrate binding Source: MGI
  4. phosphatidylinositol-4,5-bisphosphate 3-kinase activity Source: RefGenome

GO - Biological processi

  1. cellular calcium ion homeostasis Source: MGI
  2. embryonic cleavage Source: MGI
  3. homophilic cell adhesion via plasma membrane adhesion molecules Source: MGI
  4. phosphatidylinositol-3-phosphate biosynthetic process Source: GOC
  5. phosphatidylinositol-mediated signaling Source: InterPro
  6. platelet activation Source: MGI
  7. regulation of cell-matrix adhesion Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformImported
Gene namesi
Name:Pik3cbImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 9

Organism-specific databases

MGIiMGI:1922019. Pik3cb.

Subcellular locationi

GO - Cellular componenti

  1. phosphatidylinositol 3-kinase complex Source: RefGenome
  2. plasma membrane Source: RefGenome
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiD3Z2Z7.

Expressioni

Gene expression databases

BgeeiD3Z2Z7.
ExpressionAtlasiD3Z2Z7. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliD3Z2Z7.
SMRiD3Z2Z7. Positions 13-68.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000119110.

Family and domain databases

InterProiIPR003113. PI3K_adapt-bd_dom.
IPR015433. PI_Kinase.
[Graphical view]
PANTHERiPTHR10048. PTHR10048. 1 hit.
PfamiPF02192. PI3K_p85B. 1 hit.
[Graphical view]
PROSITEiPS51544. PI3K_ABD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

D3Z2Z7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPPAMADNLD IWAVDSQIAS DGAISVDFLL PTGIYIQLEV PREATISYIK
60
QMLWKQVHNY PMFNLLMD
Length:68
Mass (Da):7,741
Last modified:April 20, 2010 - v1
Checksum:i90E5B4E63EAE2664
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei68 – 681Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC120148 Genomic DNA. No translation available.
AC122930 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000124723; ENSMUSP00000121466; ENSMUSG00000032462.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC120148 Genomic DNA. No translation available.
AC122930 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali D3Z2Z7.
SMRi D3Z2Z7. Positions 13-68.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi D3Z2Z7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000124723 ; ENSMUSP00000121466 ; ENSMUSG00000032462 .

Organism-specific databases

MGIi MGI:1922019. Pik3cb.

Phylogenomic databases

GeneTreei ENSGT00760000119110.

Miscellaneous databases

NextBioi 35550656.
SOURCEi Search...

Gene expression databases

Bgeei D3Z2Z7.
ExpressionAtlasi D3Z2Z7. baseline and differential.

Family and domain databases

InterProi IPR003113. PI3K_adapt-bd_dom.
IPR015433. PI_Kinase.
[Graphical view ]
PANTHERi PTHR10048. PTHR10048. 1 hit.
Pfami PF02192. PI3K_p85B. 1 hit.
[Graphical view ]
PROSITEi PS51544. PI3K_ABD. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiD3Z2Z7_MOUSE
AccessioniPrimary (citable) accession number: D3Z2Z7
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: November 26, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3