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D3Z2C4

- D3Z2C4_MOUSE

UniProt

D3Z2C4 - D3Z2C4_MOUSE

Protein
Submitted name:

Pyruvate kinase PKLR

Gene

Pklr

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. magnesium ion binding Source: InterPro
    2. potassium ion binding Source: InterPro
    3. pyruvate kinase activity Source: MGI

    GO - Biological processi

    1. ATP biosynthetic process Source: Ensembl
    2. cellular response to insulin stimulus Source: Ensembl
    3. glycolytic process Source: InterPro
    4. phosphorylation Source: GOC
    5. pyruvate biosynthetic process Source: Ensembl
    6. response to ATP Source: Ensembl
    7. response to cAMP Source: Ensembl
    8. response to glucose Source: Ensembl
    9. response to heat Source: Ensembl
    10. response to hypoxia Source: Ensembl
    11. response to lithium ion Source: Ensembl
    12. response to nutrient Source: Ensembl
    13. response to other organism Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Pyruvate kinase PKLRImported
    Gene namesi
    Name:PklrImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 3

    Organism-specific databases

    MGIiMGI:97604. Pklr.

    Subcellular locationi

    GO - Cellular componenti

    1. cytosol Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiD3Z2C4.
    BgeeiD3Z2C4.

    Structurei

    3D structure databases

    ProteinModelPortaliD3Z2C4.
    SMRiD3Z2C4. Positions 1-72.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00390000008859.

    Family and domain databases

    Gene3Di3.20.20.60. 1 hit.
    InterProiIPR001697. Pyr_Knase.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    IPR015793. Pyrv_Knase_brl.
    [Graphical view]
    PANTHERiPTHR11817. PTHR11817. 1 hit.
    PfamiPF00224. PK. 1 hit.
    [Graphical view]
    SUPFAMiSSF51621. SSF51621. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    D3Z2C4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MADTFLEHLC LLDIDSEPVA ARSTSIIATI GPASRSVDRL KEMIKAGMNI   50
    ARLNFSHGSH EYHAESIANI RE 72
    Length:72
    Mass (Da):7,923
    Last modified:April 20, 2010 - v1
    Checksum:i663BD4B262F1DE05
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei72 – 721Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC161600 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000127058; ENSMUSP00000119392; ENSMUSG00000041237.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC161600 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali D3Z2C4.
    SMRi D3Z2C4. Positions 1-72.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000127058 ; ENSMUSP00000119392 ; ENSMUSG00000041237 .

    Organism-specific databases

    MGIi MGI:97604. Pklr.

    Phylogenomic databases

    GeneTreei ENSGT00390000008859.

    Miscellaneous databases

    ChiTaRSi PKLR. mouse.
    NextBioi 35550487.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi D3Z2C4.
    Bgeei D3Z2C4.

    Family and domain databases

    Gene3Di 3.20.20.60. 1 hit.
    InterProi IPR001697. Pyr_Knase.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    IPR015793. Pyrv_Knase_brl.
    [Graphical view ]
    PANTHERi PTHR11817. PTHR11817. 1 hit.
    Pfami PF00224. PK. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51621. SSF51621. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiD3Z2C4_MOUSE
    AccessioniPrimary (citable) accession number: D3Z2C4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 20, 2010
    Last sequence update: April 20, 2010
    Last modified: October 1, 2014
    This is version 35 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3