D3Z2C4 (D3Z2C4_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Pyruvate kinase isozymes R/L Ensembl ENSMUSP00000119392

Gene names

Name:

Pklr Ensembl ENSMUSP00000119392 MGI 97604

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000119392

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	72 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000119392

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	ATP biosynthetic process Inferred from electronic annotation. Source: Compara cellular response to insulin stimulus Inferred from electronic annotation. Source: Compara glycolysis Inferred from electronic annotation. Source: InterPro pyruvate biosynthetic process Inferred from electronic annotation. Source: Compara response to ATP Inferred from electronic annotation. Source: Compara response to cAMP Inferred from electronic annotation. Source: Compara response to glucose stimulus Inferred from electronic annotation. Source: Compara response to heat Inferred from electronic annotation. Source: Compara response to hypoxia Inferred from electronic annotation. Source: Compara response to lithium ion Inferred from electronic annotation. Source: Compara response to nutrient Inferred from electronic annotation. Source: Compara response to other organism Inferred from mutant phenotype PubMed 14595440. Source: MGI
Cellular_component	cytosol Inferred from electronic annotation. Source: Compara
Molecular_function	magnesium ion binding Inferred from electronic annotation. Source: InterPro potassium ion binding Inferred from electronic annotation. Source: InterPro pyruvate kinase activity Inferred from direct assay PubMed 15155459PubMed 7295297. Source: MGI
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	72	1	Ensembl ENSMUSP00000119392

Sequences

	Sequence		Length	Mass (Da)
	D3Z2C4 [UniParc]. Last modified April 20, 2010. Version 1. Checksum: 663BD4B262F1DE05	FASTA	72	7,923
	10 20 30 40 50 60 MADTFLEHLC LLDIDSEPVA ARSTSIIATI GPASRSVDRL KEMIKAGMNI ARLNFSHGSH 70 EYHAESIANI RE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000119392.
[2]	Ensembl Submitted (MAY-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000119392.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC161600 Genomic DNA. No translation available.
IPI	IPI00776364.
3D structure databases
ProteinModelPortal	D3Z2C4.
SMR	D3Z2C4. Positions 1-72.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000127058; ENSMUSP00000119392; ENSMUSG00000041237.
Organism-specific databases
MGI	MGI:97604. Pklr.
Phylogenomic databases
GeneTree	ENSGT00390000008859.
Gene expression databases
ArrayExpress	D3Z2C4.
Bgee	D3Z2C4.
Family and domain databases
Gene3D	3.20.20.60. 1 hit.
InterPro	IPR001697. Pyr_Knase. IPR015813. Pyrv/PenolPyrv_Kinase. IPR015793. Pyrv_Knase_brl. [Graphical view]
PANTHER	PTHR11817. PTHR11817. 1 hit.
Pfam	PF00224. PK. 1 hit. [Graphical view]
SUPFAM	SSF51621. Pyrv/PenolPyrv_Kinase_cat. 1 hit.
ProtoNet	Search...
Other
ChiTaRS	PKLR. mouse.
NextBio	35550487.
SOURCE	Search...

Entry information

Entry name

D3Z2C4_MOUSE

Accession

Primary (citable) accession number: D3Z2C4

Entry history

Integrated into UniProtKB/TrEMBL:	April 20, 2010
Last sequence update:	April 20, 2010
Last modified:	April 3, 2013
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)