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Protein
Submitted name:

Pyruvate kinase PKLR

Gene

Pklr

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • magnesium ion binding Source: InterPro
  • potassium ion binding Source: InterPro
  • pyruvate kinase activity Source: MGI

GO - Biological processi

  • response to other organism Source: MGI
Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-MMU-70171. Glycolysis.

Names & Taxonomyi

Protein namesi
Submitted name:
Pyruvate kinase PKLRImported
Gene namesi
Name:PklrImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 3

Organism-specific databases

MGIiMGI:97604. Pklr.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiD3Z2C4.

Expressioni

Gene expression databases

BgeeiD3Z2C4.
ExpressionAtlasiD3Z2C4. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000035417.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini22 – 7251PKInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiCOG0469. LUCA.
KOG2323. Eukaryota.
GeneTreeiENSGT00390000008859.

Family and domain databases

Gene3Di3.20.20.60. 1 hit.
InterProiIPR001697. Pyr_Knase.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
IPR015793. Pyrv_Knase_brl.
[Graphical view]
PANTHERiPTHR11817. PTHR11817. 1 hit.
PfamiPF00224. PK. 1 hit.
[Graphical view]
SUPFAMiSSF51621. SSF51621. 1 hit.

Sequencei

Sequence statusi: Fragment.

D3Z2C4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADTFLEHLC LLDIDSEPVA ARSTSIIATI GPASRSVDRL KEMIKAGMNI
60 70
ARLNFSHGSH EYHAESIANI RE
Length:72
Mass (Da):7,923
Last modified:April 20, 2010 - v1
Checksum:i663BD4B262F1DE05
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei72 – 721Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC161600 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000127058; ENSMUSP00000119392; ENSMUSG00000041237.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC161600 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000035417.

Proteomic databases

PaxDbiD3Z2C4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000127058; ENSMUSP00000119392; ENSMUSG00000041237.

Organism-specific databases

MGIiMGI:97604. Pklr.

Phylogenomic databases

eggNOGiCOG0469. LUCA.
KOG2323. Eukaryota.
GeneTreeiENSGT00390000008859.

Enzyme and pathway databases

ReactomeiR-MMU-70171. Glycolysis.

Miscellaneous databases

ChiTaRSiPklr. mouse.
NextBioi35550487.
SOURCEiSearch...

Gene expression databases

BgeeiD3Z2C4.
ExpressionAtlasiD3Z2C4. baseline and differential.

Family and domain databases

Gene3Di3.20.20.60. 1 hit.
InterProiIPR001697. Pyr_Knase.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
IPR015793. Pyrv_Knase_brl.
[Graphical view]
PANTHERiPTHR11817. PTHR11817. 1 hit.
PfamiPF00224. PK. 1 hit.
[Graphical view]
SUPFAMiSSF51621. SSF51621. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiD3Z2C4_MOUSE
AccessioniPrimary (citable) accession number: D3Z2C4
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: December 9, 2015
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.