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Protein
Submitted name:

Dipeptidyl peptidase 1

Gene

Ctsc

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. cysteine-type peptidase activity Source: MGI
  2. peptidase activator activity involved in apoptotic process Source: MGI

GO - Biological processi

  1. apoptotic process Source: GOC
  2. positive regulation of apoptotic signaling pathway Source: MGI
  3. proteolysis Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Dipeptidyl peptidase 1Imported
Gene namesi
Name:CtscImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 7

Organism-specific databases

MGIiMGI:109553. Ctsc.

Subcellular locationi

GO - Cellular componenti

  1. extracellular space Source: MGI
  2. extracellular vesicular exosome Source: MGI
  3. membrane Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiD3Z220.
ExpressionAtlasiD3Z220. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliD3Z220.
SMRiD3Z220. Positions 25-254.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000118871.
HOGENOMiHOG000068022.

Family and domain databases

Gene3Di2.40.128.80. 1 hit.
InterProiIPR014882. CathepsinC_exc.
IPR013128. Peptidase_C1A.
[Graphical view]
PANTHERiPTHR12411. PTHR12411. 1 hit.
PfamiPF08773. CathepsinC_exc. 1 hit.
[Graphical view]
SUPFAMiSSF75001. SSF75001. 1 hit.

Sequencei

Sequence statusi: Fragment.

D3Z220-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGPWTHSLRA VLLLVLLGVC TVRSDTPANC TYPDLLGTWV FQVGPRSSRS
60 70 80 90 100
DINCSVMATE EKVVVHLKKL DTAYDELGNS GHFTLIYNQG FEIVLNDYKW
110 120 130 140 150
FAFFKYEVRG HTAISYCHET MTGWVHDVLG RNWACFVGKK VESHIEKVNM
160 170 180 190 200
NAAHLGGLQE RYSERLYTHN HNFVKAINTV QKSWTATAYK EYEKMSLRDL
210 220 230 240 250
IRRSGHSQRI PRPKPAPMTD EIQQQILNLP ESWDWRNVQG VNYVSPVRNQ

ESCG
Length:254
Mass (Da):29,178
Last modified:April 20, 2010 - v1
Checksum:i2666AB2012A569FF
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei254 – 2541Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124322 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000128791; ENSMUSP00000119503; ENSMUSG00000030560.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124322 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliD3Z220.
SMRiD3Z220. Positions 25-254.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000128791; ENSMUSP00000119503; ENSMUSG00000030560.

Organism-specific databases

MGIiMGI:109553. Ctsc.

Phylogenomic databases

GeneTreeiENSGT00760000118871.
HOGENOMiHOG000068022.

Miscellaneous databases

ChiTaRSiCtsc. mouse.
NextBioi35550420.
SOURCEiSearch...

Gene expression databases

BgeeiD3Z220.
ExpressionAtlasiD3Z220. baseline and differential.

Family and domain databases

Gene3Di2.40.128.80. 1 hit.
InterProiIPR014882. CathepsinC_exc.
IPR013128. Peptidase_C1A.
[Graphical view]
PANTHERiPTHR12411. PTHR12411. 1 hit.
PfamiPF08773. CathepsinC_exc. 1 hit.
[Graphical view]
SUPFAMiSSF75001. SSF75001. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiD3Z220_MOUSE
AccessioniPrimary (citable) accession number: D3Z220
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: February 4, 2015
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.