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Protein
Submitted name:

Intraflagellar transport protein 80 homolog

Gene

Ift80

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • bone morphogenesis Source: MGI
  • chondrocyte differentiation Source: MGI
  • cilium assembly Source: MGI
  • cilium morphogenesis Source: MGI
  • intraciliary transport Source: MGI
  • negative regulation of epithelial cell proliferation Source: MGI
  • negative regulation of non-canonical Wnt signaling pathway Source: MGI
  • osteoblast differentiation Source: MGI
  • positive regulation of smoothened signaling pathway Source: MGI
  • smoothened signaling pathway Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Intraflagellar transport protein 80 homologImported
Gene namesi
Name:Ift80Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 3

Organism-specific databases

MGIiMGI:1915509. Ift80.

Subcellular locationi

GO - Cellular componenti

  • centrosome Source: MGI
  • ciliary basal body Source: MGI
  • cilium Source: MGI
  • intraciliary transport particle B Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiD3Z157.
ExpressionAtlasiD3Z157. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliD3Z157.
SMRiD3Z157. Positions 10-159.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

RepeatUniRule annotation, WD repeatUniRule annotation

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00400. WD40. 1 hit.
[Graphical view]
SMARTiSM00320. WD40. 2 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS50082. WD_REPEATS_2. 1 hit.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

D3Z157-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLKISLSKE PKHQELVSCV GWTTAEELYS CSDDHQIVKW NLLTSETSLI
60 70 80 90 100
VKLPDDIYPI DLHWFPKSLG IKKQTQAESF VLTSSDGKFH LISKLGRVEK
110 120 130 140 150
SVEAHCGAVL AGRWNYEGTA LVTVGEDGQV KIWSKTGMLR STLAQQGTPV

YSVAWGPDS
Length:159
Mass (Da):17,661
Last modified:May 27, 2015 - v5
Checksum:i31316504589BBA51
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei159 – 1591Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC115062 Genomic DNA. No translation available.
AC122876 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000148031; ENSMUSP00000122919; ENSMUSG00000027778.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC115062 Genomic DNA. No translation available.
AC122876 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliD3Z157.
SMRiD3Z157. Positions 10-159.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000148031; ENSMUSP00000122919; ENSMUSG00000027778.

Organism-specific databases

MGIiMGI:1915509. Ift80.

Miscellaneous databases

ChiTaRSiIft80. mouse.
NextBioi35550208.
SOURCEiSearch...

Gene expression databases

BgeeiD3Z157.
ExpressionAtlasiD3Z157. baseline and differential.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00400. WD40. 1 hit.
[Graphical view]
SMARTiSM00320. WD40. 2 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS50082. WD_REPEATS_2. 1 hit.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. "A tissue-specific atlas of mouse protein phosphorylation and expression."
    Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.
    Cell 143:1174-1189(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiD3Z157_MOUSE
AccessioniPrimary (citable) accession number: D3Z157
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: May 27, 2015
Last modified: May 27, 2015
This is version 36 of the entry and version 5 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.