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D3Z136

- D3Z136_MOUSE

UniProt

D3Z136 - D3Z136_MOUSE

Protein

Elongation of very long chain fatty acids protein

Gene

Elovl5

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 32 (01 Oct 2014)
      Sequence version 1 (20 Apr 2010)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    A very-long-chain acyl-CoA + malonyl-CoA = CoA + a very-long-chain 3-oxoacyl-CoA + CO2.UniRule annotation

    GO - Molecular functioni

    1. fatty acid elongase activity Source: Ensembl

    GO - Biological processi

    1. fatty acid elongation, monounsaturated fatty acid Source: Ensembl
    2. fatty acid elongation, polyunsaturated fatty acid Source: Ensembl
    3. very long-chain fatty acid biosynthetic process Source: Ensembl

    Keywords - Molecular functioni

    TransferaseUniRule annotation

    Keywords - Biological processi

    Fatty acid biosynthesisUniRule annotation, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation of very long chain fatty acids proteinUniRule annotation (EC:2.3.1.199UniRule annotation)
    Alternative name(s):
    Very-long-chain 3-oxoacyl-CoA synthaseUniRule annotation
    Gene namesi
    Name:Elovl5Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 9

    Organism-specific databases

    MGIiMGI:1916051. Elovl5.

    Subcellular locationi

    GO - Cellular componenti

    1. endoplasmic reticulum Source: Ensembl
    2. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    Expressioni

    Gene expression databases

    ArrayExpressiD3Z136.
    BgeeiD3Z136.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ELO family.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixUniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00740000115242.
    HOGENOMiHOG000038120.

    Family and domain databases

    InterProiIPR002076. GNS1_SUR4.
    [Graphical view]
    PANTHERiPTHR11157. PTHR11157. 1 hit.
    PfamiPF01151. ELO. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    D3Z136-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEHFDASLST YFKAFLGPRD TRVKGWFLLD NYIPTFVCSV IYLLIVWLGP    50
    KYMKNRQPFS CRGILQLYNL GLTLLSLYMF YELVTGVWEG KYNFFCQGTR 100
    SAGESDMKII RVLWWYYFSK LIEFMDTFFF ILRKNNHQIT VLHVYHHATM 150
    LNIWWFVMNW VPCGHSYFGA TLNSFIHVLM 180
    Length:180
    Mass (Da):21,543
    Last modified:April 20, 2010 - v1
    Checksum:i38D9289152A2B4C0
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei180 – 1801Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC159886 Genomic DNA. No translation available.
    AC160334 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000133757; ENSMUSP00000123121; ENSMUSG00000032349.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC159886 Genomic DNA. No translation available.
    AC160334 Genomic DNA. No translation available.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000133757 ; ENSMUSP00000123121 ; ENSMUSG00000032349 .

    Organism-specific databases

    MGIi MGI:1916051. Elovl5.

    Phylogenomic databases

    GeneTreei ENSGT00740000115242.
    HOGENOMi HOG000038120.

    Miscellaneous databases

    ChiTaRSi ELOVL5. mouse.
    NextBioi 35550194.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi D3Z136.
    Bgeei D3Z136.

    Family and domain databases

    InterProi IPR002076. GNS1_SUR4.
    [Graphical view ]
    PANTHERi PTHR11157. PTHR11157. 1 hit.
    Pfami PF01151. ELO. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiD3Z136_MOUSE
    AccessioniPrimary (citable) accession number: D3Z136
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 20, 2010
    Last sequence update: April 20, 2010
    Last modified: October 1, 2014
    This is version 32 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation
    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3