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D3Z0Q9

- D3Z0Q9_MOUSE

UniProt

D3Z0Q9 - D3Z0Q9_MOUSE

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Protein

Sodium/hydrogen exchanger

Gene

Slc9a6

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. sodium:proton antiporter activity Source: InterPro

GO - Biological processi

  1. axon extension Source: MGI
  2. brain-derived neurotrophic factor receptor signaling pathway Source: MGI
  3. dendrite extension Source: MGI
  4. dendritic spine development Source: MGI
  5. neuron projection morphogenesis Source: MGI
  6. proton transport Source: MGI
  7. regulation of neurotrophin TRK receptor signaling pathway Source: MGI
  8. regulation of pH Source: InterPro
  9. synapse organization Source: MGI
Complete GO annotation...

Keywords - Biological processi

AntiportUniRule annotation, Ion transport, Sodium transportUniRule annotation, Transport

Keywords - Ligandi

Sodium

Enzyme and pathway databases

ReactomeiREACT_259261. Sodium/Proton exchangers.

Names & Taxonomyi

Protein namesi
Recommended name:
Sodium/hydrogen exchangerUniRule annotation
Gene namesi
Name:Slc9a6Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome X

Organism-specific databases

MGIiMGI:2443511. Slc9a6.

Subcellular locationi

GO - Cellular componenti

  1. axonal spine Source: MGI
  2. axon terminus Source: MGI
  3. cytoplasmic vesicle Source: MGI
  4. dendrite Source: MGI
  5. early endosome Source: MGI
  6. early endosome membrane Source: Ensembl
  7. endoplasmic reticulum membrane Source: Ensembl
  8. endosome Source: MGI
  9. integral component of membrane Source: UniProtKB-KW
  10. late endosome Source: MGI
  11. mitochondrion Source: MGI
  12. plasma membrane Source: MGI
  13. recycling endosome Source: MGI
  14. recycling endosome membrane Source: Ensembl
  15. synapse Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

MaxQBiD3Z0Q9.

Expressioni

Gene expression databases

BgeeiD3Z0Q9.
ExpressionAtlasiD3Z0Q9. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliD3Z0Q9.
SMRiD3Z0Q9. Positions 198-226.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. [View classification]UniRule annotation

Keywords - Domaini

TransmembraneUniRule annotation

Phylogenomic databases

GeneTreeiENSGT00760000119074.
HOGENOMiHOG000172307.

Family and domain databases

InterProiIPR006153. Cation/H_exchanger.
IPR018422. Cation/H_exchanger_CPA1.
IPR002090. Na/H_exchanger_6.
IPR004709. NaH_exchanger.
[Graphical view]
PANTHERiPTHR10110. PTHR10110. 1 hit.
PfamiPF00999. Na_H_Exchanger. 1 hit.
[Graphical view]
PRINTSiPR01084. NAHEXCHNGR.
PR01088. NAHEXCHNGR6.

Sequencei

Sequence statusi: Fragment.

D3Z0Q9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDEEIVSEKQ AEESHRQDSA NLLIFILLLT LTILTIWLFK HRRARFLHET
60 70 80 90 100
GLAMIYGLLV GLVLRYGIHV PSDVNNVTLS CEVQSSPTTL LVNVSGKFYE
110 120 130 140 150
YTLKGEISSH ELNNVQDNEM LRKVTFDPEV FFNILLPPII FYAGYSLKRR
160 170 180 190 200
HFFRNLGSIL AYAFLGTAIS CFVIGSIMYG CVTLMKVTGQ LAGDFYFTDC
210 220 230 240 250
LLFGAIVSAT DPVTVLAIFH ELQVDVELYA LLFGESVLND AVAIVLSSSI
260 270 280 290
VAYQPAGDNS HTFDVTAMFK SIGIFLGIFS GSFAMGAATG V
Length:291
Mass (Da):32,126
Last modified:April 20, 2010 - v1
Checksum:i930DB38FF3BFB2B0
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei291 – 2911Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC048362 Genomic DNA. No translation available.
AL672085 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000144068; ENSMUSP00000115364; ENSMUSG00000060681.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC048362 Genomic DNA. No translation available.
AL672085 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali D3Z0Q9.
SMRi D3Z0Q9. Positions 198-226.
ModBasei Search...
MobiDBi Search...

Proteomic databases

MaxQBi D3Z0Q9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000144068 ; ENSMUSP00000115364 ; ENSMUSG00000060681 .

Organism-specific databases

MGIi MGI:2443511. Slc9a6.

Phylogenomic databases

GeneTreei ENSGT00760000119074.
HOGENOMi HOG000172307.

Enzyme and pathway databases

Reactomei REACT_259261. Sodium/Proton exchangers.

Miscellaneous databases

NextBioi 35550095.
SOURCEi Search...

Gene expression databases

Bgeei D3Z0Q9.
ExpressionAtlasi D3Z0Q9. baseline and differential.

Family and domain databases

InterProi IPR006153. Cation/H_exchanger.
IPR018422. Cation/H_exchanger_CPA1.
IPR002090. Na/H_exchanger_6.
IPR004709. NaH_exchanger.
[Graphical view ]
PANTHERi PTHR10110. PTHR10110. 1 hit.
Pfami PF00999. Na_H_Exchanger. 1 hit.
[Graphical view ]
PRINTSi PR01084. NAHEXCHNGR.
PR01088. NAHEXCHNGR6.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiD3Z0Q9_MOUSE
AccessioniPrimary (citable) accession number: D3Z0Q9
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: November 26, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3