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D3Z0Q9

- D3Z0Q9_MOUSE

UniProt

D3Z0Q9 - D3Z0Q9_MOUSE

Protein

Sodium/hydrogen exchanger

Gene

Slc9a6

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Protein inferred from homologyi
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    • History
      Entry version 31 (01 Oct 2014)
      Sequence version 1 (20 Apr 2010)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. sodium:proton antiporter activity Source: InterPro

    GO - Biological processi

    1. axon extension Source: MGI
    2. brain-derived neurotrophic factor receptor signaling pathway Source: MGI
    3. dendrite extension Source: MGI
    4. dendritic spine development Source: MGI
    5. neuron projection morphogenesis Source: MGI
    6. proton transport Source: MGI
    7. regulation of neurotrophin TRK receptor signaling pathway Source: MGI
    8. regulation of pH Source: InterPro
    9. synapse organization Source: MGI

    Keywords - Biological processi

    AntiportUniRule annotation, Ion transport, Sodium transportUniRule annotation, Transport

    Keywords - Ligandi

    Sodium

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Sodium/hydrogen exchangerUniRule annotation
    Gene namesi
    Name:Slc9a6Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome X

    Organism-specific databases

    MGIiMGI:2443511. Slc9a6.

    Subcellular locationi

    GO - Cellular componenti

    1. axonal spine Source: MGI
    2. axon terminus Source: MGI
    3. cytoplasmic vesicle Source: MGI
    4. dendrite Source: MGI
    5. early endosome Source: MGI
    6. early endosome membrane Source: Ensembl
    7. endoplasmic reticulum membrane Source: Ensembl
    8. endosome Source: MGI
    9. integral component of membrane Source: UniProtKB-KW
    10. late endosome Source: MGI
    11. mitochondrion Source: MGI
    12. plasma membrane Source: MGI
    13. recycling endosome Source: MGI
    14. recycling endosome membrane Source: Ensembl
    15. synapse Source: MGI

    Keywords - Cellular componenti

    Membrane

    Expressioni

    Gene expression databases

    BgeeiD3Z0Q9.

    Structurei

    3D structure databases

    ProteinModelPortaliD3Z0Q9.
    SMRiD3Z0Q9. Positions 198-226.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. [View classification]UniRule annotation

    Keywords - Domaini

    TransmembraneUniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00560000076802.
    HOGENOMiHOG000172307.

    Family and domain databases

    InterProiIPR006153. Cation/H_exchanger.
    IPR018422. Cation/H_exchanger_CPA1.
    IPR002090. Na/H_exchanger_6.
    IPR004709. NaH_exchanger.
    [Graphical view]
    PANTHERiPTHR10110. PTHR10110. 1 hit.
    PfamiPF00999. Na_H_Exchanger. 1 hit.
    [Graphical view]
    PRINTSiPR01084. NAHEXCHNGR.
    PR01088. NAHEXCHNGR6.

    Sequencei

    Sequence statusi: Fragment.

    D3Z0Q9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDEEIVSEKQ AEESHRQDSA NLLIFILLLT LTILTIWLFK HRRARFLHET    50
    GLAMIYGLLV GLVLRYGIHV PSDVNNVTLS CEVQSSPTTL LVNVSGKFYE 100
    YTLKGEISSH ELNNVQDNEM LRKVTFDPEV FFNILLPPII FYAGYSLKRR 150
    HFFRNLGSIL AYAFLGTAIS CFVIGSIMYG CVTLMKVTGQ LAGDFYFTDC 200
    LLFGAIVSAT DPVTVLAIFH ELQVDVELYA LLFGESVLND AVAIVLSSSI 250
    VAYQPAGDNS HTFDVTAMFK SIGIFLGIFS GSFAMGAATG V 291
    Length:291
    Mass (Da):32,126
    Last modified:April 20, 2010 - v1
    Checksum:i930DB38FF3BFB2B0
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei291 – 2911Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC048362 Genomic DNA. No translation available.
    AL672085 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000144068; ENSMUSP00000115364; ENSMUSG00000060681.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC048362 Genomic DNA. No translation available.
    AL672085 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali D3Z0Q9.
    SMRi D3Z0Q9. Positions 198-226.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000144068 ; ENSMUSP00000115364 ; ENSMUSG00000060681 .

    Organism-specific databases

    MGIi MGI:2443511. Slc9a6.

    Phylogenomic databases

    GeneTreei ENSGT00560000076802.
    HOGENOMi HOG000172307.

    Miscellaneous databases

    NextBioi 35550095.
    SOURCEi Search...

    Gene expression databases

    Bgeei D3Z0Q9.

    Family and domain databases

    InterProi IPR006153. Cation/H_exchanger.
    IPR018422. Cation/H_exchanger_CPA1.
    IPR002090. Na/H_exchanger_6.
    IPR004709. NaH_exchanger.
    [Graphical view ]
    PANTHERi PTHR10110. PTHR10110. 1 hit.
    Pfami PF00999. Na_H_Exchanger. 1 hit.
    [Graphical view ]
    PRINTSi PR01084. NAHEXCHNGR.
    PR01088. NAHEXCHNGR6.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiD3Z0Q9_MOUSE
    AccessioniPrimary (citable) accession number: D3Z0Q9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 20, 2010
    Last sequence update: April 20, 2010
    Last modified: October 1, 2014
    This is version 31 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3