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Protein
Submitted name:

DEAD (Asp-Glu-Ala-Asp) box polypeptide 23

Gene

Ddx23

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-72163 mRNA Splicing - Major Pathway
R-MMU-72165 mRNA Splicing - Minor Pathway

Names & Taxonomyi

Protein namesi
Submitted name:
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23Imported
Submitted name:
MCG18410, isoform CRA_aImported
Gene namesi
Name:Ddx23Imported
ORF Names:mCG_18410Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 15

Organism-specific databases

MGIiMGI:1921601 Ddx23

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiD3Z0M9
PeptideAtlasiD3Z0M9

Expressioni

Gene expression databases

BgeeiENSMUSG00000003360

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000003450

Structurei

3D structure databases

SMRiD3Z0M9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini390 – 418Q_MOTIFInterPro annotationAdd BLAST29
Domaini421 – 626Helicase ATP-bindingInterPro annotationAdd BLAST206
Domaini650 – 798Helicase C-terminalInterPro annotationAdd BLAST149

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili64 – 84Sequence analysisAdd BLAST21
Coiled coili163 – 200Sequence analysisAdd BLAST38
Coiled coili322 – 349Sequence analysisAdd BLAST28

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi390 – 418Q motifPROSITE-ProRule annotationAdd BLAST29

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0333 Eukaryota
ENOG410XNVG LUCA
GeneTreeiENSGT00880000138046
HOGENOMiHOG000268796
KOiK12858
OMAiKRTQSKF
OrthoDBiEOG091G032I
TreeFamiTF300527

Family and domain databases

CDDicd00079 HELICc, 1 hit
InterProiView protein in InterPro
IPR011545 DEAD/DEAH_box_helicase_dom
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR000629 RNA-helicase_DEAD-box_CS
IPR014014 RNA_helicase_DEAD_Q_motif
PfamiView protein in Pfam
PF00270 DEAD, 1 hit
PF00271 Helicase_C, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS00039 DEAD_ATP_HELICASE, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
PS51195 Q_MOTIF, 1 hit

Sequencei

Sequence statusi: Complete.

D3Z0M9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGELADKKD RDASPKEERK RSRTPERDRD RDRDRKSSPS KDRKRHRSRD
60 70 80 90 100
RRRGGSRSRS RSRSKSVERE RRHKERERDK ERDRSKKERE RDKDGHRRDK
110 120 130 140 150
DRKRSSLSPG RGKDFKSRKD RDSKKGDEDE HGDKRPKIQP LSLEELLAKK
160 170 180 190 200
KAEEEAEAKP KFLSKAEREA EALKRRQQEV EERQKMLEEE RKKRKQFQDL
210 220 230 240 250
GRKMLEDPQE RERRERRERM ERETNGNEDE EGRQKIREEK DKSKELHAIK
260 270 280 290 300
ERYLGGIKKR RRTRHLNDRK FVFEWDASED TSIDYNPLYK ERHQVQLLGR
310 320 330 340 350
GFIAGIDLKQ QKREQSRFYG DLMEKRRTLE EKEQEEARLR KLRKKEAKQR
360 370 380 390 400
WDDRHWSQKK LDEMTDRDWR IFREDYSITT KGGKIPNPIR SWKDSSLPPH
410 420 430 440 450
ILEVIDKCGY KEPTPIQRQA IPIGLQNRDI IGVAETGSGK TAAFLIPLLV
460 470 480 490 500
WITTLPKIDR IEESDQGPYA IILAPTRELA QQIEEETIKF GKPLGIRTVA
510 520 530 540 550
VIGGISREDQ GFRLRMGCEI VIATPGRLID VLENRYLVLS RCTYVVLDEA
560 570 580 590 600
DRMIDMGFEP DVQKILEHMP VSNQKPDTDE AEDPEKMLAN FESGKHKYRQ
610 620 630 640 650
TVMFTATMPP AVERLARSYL RRPAVVYIGS AGKPHERVEQ KVFLMSESEK
660 670 680 690 700
RKKLLAILEQ GFDPPIIIFV NQKKGCDVLA KSLEKMGYNA CTLHGGKGQE
710 720 730 740 750
QREFALSNLK AGAKDILVAT DVAGRGIDIQ DVSMVVNYDM AKNIEDYIHR
760 770 780 790 800
IGRTGRAGKS GVAITFLTKE DSAVFYELKQ AILESPVSSC PPELANHPDA
810
QHKPGTILTK KRREETIFA
Length:819
Mass (Da):95,495
Last modified:April 20, 2010 - v1
Checksum:i55D2738CEE657639
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC156543 Genomic DNA No translation available.
CH466550 Genomic DNA Translation: EDL04176.1
RefSeqiNP_001074450.1, NM_001080981.1
XP_006521556.1, XM_006521493.3
UniGeneiMm.45725

Genome annotation databases

EnsembliENSMUST00000003450; ENSMUSP00000003450; ENSMUSG00000003360
GeneIDi74351
KEGGimmu:74351
UCSCiuc007xne.1 mouse

Similar proteinsi

Entry informationi

Entry nameiD3Z0M9_MOUSE
AccessioniPrimary (citable) accession number: D3Z0M9
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: April 25, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health