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Protein
Submitted name:

Alpha-actinin-4

Gene

Actn4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActin-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha-actinin-4Imported
Gene namesi
Name:Actn4Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:1890773. Actn4.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiD3Z0L8.
PaxDbiD3Z0L8.
PeptideAtlasiD3Z0L8.
PRIDEiD3Z0L8.

Expressioni

Gene expression databases

BgeeiENSMUSG00000054808.
ExpressionAtlasiD3Z0L8. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliD3Z0L8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 70Calponin-homology (CH)InterPro annotationAdd BLAST70
Domaini79 – 182Calponin-homology (CH)InterPro annotationAdd BLAST104

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

eggNOGiKOG0035. Eukaryota.
COG5069. LUCA.
GeneTreeiENSGT00760000118813.
HOGENOMiHOG000205447.

Family and domain databases

CDDicd00014. CH. 2 hits.
Gene3Di1.10.418.10. 2 hits.
InterProiView protein in InterPro
IPR001589. Actinin_actin-bd_CS.
IPR029637. ACTN4.
IPR036872. Calponin-like_dom_sf.
IPR001715. CH-domain.
PANTHERiPTHR43947:SF7. PTHR43947:SF7. 1 hit.
PfamiView protein in Pfam
PF00307. CH. 2 hits.
SMARTiView protein in SMART
SM00033. CH. 2 hits.
SUPFAMiSSF47576. SSF47576. 1 hit.
PROSITEiView protein in PROSITE
PS00020. ACTININ_2. 1 hit.
PS50021. CH. 2 hits.

Sequencei

Sequence statusi: Fragment.

D3Z0L8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLLEVISGE RLPKPERGKM RVHKINNVNK ALDFIASKGV KLVSIGAEEI
60 70 80 90 100
VDGNAKMTLG MIWTIILRFA IQDISVEETS AKEGLLLWCQ RKTAPYKNVN
110 120 130 140 150
VQNFHISWKD GLAFNALIHR HRPELIEYDK LRKDDPVTNL NNAFEVAEKY
160 170 180 190 200
LDIPKMLDAE DIVNTARPDE KAIMTYVSSF YHAFSGAQKA ETAANRICKV

LAVNQE
Length:206
Mass (Da):23,309
Last modified:April 20, 2010 - v1
Checksum:i87B2DB8A6E4BEB18
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei206Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC166357 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000140622; ENSMUSP00000123210; ENSMUSG00000054808.

Similar proteinsi

Entry informationi

Entry nameiD3Z0L8_MOUSE
AccessioniPrimary (citable) accession number: D3Z0L8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: October 25, 2017
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported