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Protein
Submitted name:

Alpha-actinin-4

Gene

Actn4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

Actin-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha-actinin-4Imported
Gene namesi
Name:Actn4Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:1890773. Actn4.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

MaxQBiD3Z0L8.
PaxDbiD3Z0L8.
PeptideAtlasiD3Z0L8.
PRIDEiD3Z0L8.

Expressioni

Gene expression databases

BgeeiENSMUSG00000054808.
ExpressionAtlasiD3Z0L8. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000066068.

Structurei

3D structure databases

ProteinModelPortaliD3Z0L8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 70Actin-bindingInterPro annotationAdd BLAST70
Domaini79 – 182Actin-bindingInterPro annotationAdd BLAST104

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

eggNOGiKOG0035. Eukaryota.
COG5069. LUCA.
GeneTreeiENSGT00760000118813.
HOGENOMiHOG000205447.

Family and domain databases

CDDicd00014. CH. 2 hits.
Gene3Di1.10.418.10. 2 hits.
InterProiIPR001589. Actinin_actin-bd_CS.
IPR029637. ACTN4.
IPR001715. CH-domain.
[Graphical view]
PANTHERiPTHR11915:SF271. PTHR11915:SF271. 1 hit.
PfamiPF00307. CH. 2 hits.
[Graphical view]
SMARTiSM00033. CH. 2 hits.
[Graphical view]
SUPFAMiSSF47576. SSF47576. 1 hit.
PROSITEiPS00020. ACTININ_2. 1 hit.
PS50021. CH. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

D3Z0L8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLLEVISGE RLPKPERGKM RVHKINNVNK ALDFIASKGV KLVSIGAEEI
60 70 80 90 100
VDGNAKMTLG MIWTIILRFA IQDISVEETS AKEGLLLWCQ RKTAPYKNVN
110 120 130 140 150
VQNFHISWKD GLAFNALIHR HRPELIEYDK LRKDDPVTNL NNAFEVAEKY
160 170 180 190 200
LDIPKMLDAE DIVNTARPDE KAIMTYVSSF YHAFSGAQKA ETAANRICKV

LAVNQE
Length:206
Mass (Da):23,309
Last modified:April 20, 2010 - v1
Checksum:i87B2DB8A6E4BEB18
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei206Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC166357 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000140622; ENSMUSP00000123210; ENSMUSG00000054808.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC166357 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliD3Z0L8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000066068.

Proteomic databases

MaxQBiD3Z0L8.
PaxDbiD3Z0L8.
PeptideAtlasiD3Z0L8.
PRIDEiD3Z0L8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000140622; ENSMUSP00000123210; ENSMUSG00000054808.

Organism-specific databases

MGIiMGI:1890773. Actn4.

Phylogenomic databases

eggNOGiKOG0035. Eukaryota.
COG5069. LUCA.
GeneTreeiENSGT00760000118813.
HOGENOMiHOG000205447.

Miscellaneous databases

ChiTaRSiActn4. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000054808.
ExpressionAtlasiD3Z0L8. baseline and differential.

Family and domain databases

CDDicd00014. CH. 2 hits.
Gene3Di1.10.418.10. 2 hits.
InterProiIPR001589. Actinin_actin-bd_CS.
IPR029637. ACTN4.
IPR001715. CH-domain.
[Graphical view]
PANTHERiPTHR11915:SF271. PTHR11915:SF271. 1 hit.
PfamiPF00307. CH. 2 hits.
[Graphical view]
SMARTiSM00033. CH. 2 hits.
[Graphical view]
SUPFAMiSSF47576. SSF47576. 1 hit.
PROSITEiPS00020. ACTININ_2. 1 hit.
PS50021. CH. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiD3Z0L8_MOUSE
AccessioniPrimary (citable) accession number: D3Z0L8
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: November 30, 2016
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.