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Protein
Submitted name:

Sodium/glucose cotransporter 2

Gene

Slc5a2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. transporter activity Source: InterPro

GO - Biological processi

  1. transmembrane transport Source: InterPro
Complete GO annotation...

Keywords - Biological processi

TransportUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Sodium/glucose cotransporter 2Imported
Gene namesi
Name:Slc5a2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:2181411. Slc5a2.

Subcellular locationi

  1. Membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

GO - Cellular componenti

  1. extracellular vesicular exosome Source: MGI
  2. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiD3Z0A1.

Expressioni

Gene expression databases

BgeeiD3Z0A1.
ExpressionAtlasiD3Z0A1. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliD3Z0A1.
SMRiD3Z0A1. Positions 20-232.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. [View classification]UniRule annotation

Keywords - Domaini

TransmembraneUniRule annotation

Phylogenomic databases

GeneTreeiENSGT00760000118955.
HOGENOMiHOG000025422.

Family and domain databases

InterProiIPR001734. Na/solute_symporter.
IPR018212. Na/solute_symporter_CS.
IPR019900. Na/solute_symporter_subgr.
[Graphical view]
PANTHERiPTHR11819. PTHR11819. 1 hit.
PfamiPF00474. SSF. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00813. sss. 1 hit.
PROSITEiPS00456. NA_SOLUT_SYMP_1. 1 hit.
PS50283. NA_SOLUT_SYMP_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

D3Z0A1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEQHVEAGSE LGEQKVLIDN PADILVIAAY FLLVIGVGLW SMFRTNRGTV
60 70 80 90 100
GGYFLAGRSM VGASLFASNI GSGHFVGLAG TGAASGLAVA GFEWNALFVV
110 120 130 140 150
LLLGWLFVPV YLTAGVITMP QYLRKRFGGH RIRLYLSVLS LFLYIFTKIS
160 170 180 190 200
VDMFSGAVFI QQALGWNIYA SVIALLGITM IYTVTGGLAA LMYTDTVQTF
210 220 230 240 250
VILAGAFILT GYAFHEVGGY SGLFDKYLGA MTSLTVSKDP SVGNISSTCY
260 270
QPRPDSYHLL RDPVTGDLPW PALLLG
Length:276
Mass (Da):29,679
Last modified:April 20, 2010 - v1
Checksum:iABF14EC785E41E6A
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei276 – 2761Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124566 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000142841; ENSMUSP00000115451; ENSMUSG00000030781.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124566 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliD3Z0A1.
SMRiD3Z0A1. Positions 20-232.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiD3Z0A1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000142841; ENSMUSP00000115451; ENSMUSG00000030781.

Organism-specific databases

MGIiMGI:2181411. Slc5a2.

Phylogenomic databases

GeneTreeiENSGT00760000118955.
HOGENOMiHOG000025422.

Miscellaneous databases

NextBioi35549995.
SOURCEiSearch...

Gene expression databases

BgeeiD3Z0A1.
ExpressionAtlasiD3Z0A1. baseline and differential.

Family and domain databases

InterProiIPR001734. Na/solute_symporter.
IPR018212. Na/solute_symporter_CS.
IPR019900. Na/solute_symporter_subgr.
[Graphical view]
PANTHERiPTHR11819. PTHR11819. 1 hit.
PfamiPF00474. SSF. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00813. sss. 1 hit.
PROSITEiPS00456. NA_SOLUT_SYMP_1. 1 hit.
PS50283. NA_SOLUT_SYMP_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiD3Z0A1_MOUSE
AccessioniPrimary (citable) accession number: D3Z0A1
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: February 4, 2015
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.