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D3Z079

- D3Z079_MOUSE

UniProt

D3Z079 - D3Z079_MOUSE

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Protein
Submitted name:

Syntaxin-binding protein 5

Gene

Stxbp5

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. syntaxin-1 binding Source: MGI
  2. syntaxin binding Source: MGI

GO - Biological processi

  1. exocytosis Source: MGI
  2. regulation of blood coagulation Source: Ensembl
  3. regulation of exocytosis Source: MGI
  4. regulation of gene expression Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Syntaxin-binding protein 5Imported
Gene namesi
Name:Stxbp5Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 10

Organism-specific databases

MGIiMGI:1926058. Stxbp5.

Subcellular locationi

GO - Cellular componenti

  1. acetylcholine-gated channel complex Source: MGI
  2. cytoplasm Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiD3Z079.

Expressioni

Gene expression databases

BgeeiD3Z079.
ExpressionAtlasiD3Z079. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliD3Z079.
SMRiD3Z079. Positions 56-87, 194-268, 437-468, 505-532, 1052-1108.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

RepeatUniRule annotation, WD repeatUniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000000018.
HOGENOMiHOG000110929.
KOiK08518.
TreeFamiTF314585.

Family and domain databases

Gene3Di2.130.10.10. 3 hits.
InterProiIPR000664. Lethal2_giant.
IPR013905. Lgl_C_dom.
IPR013577. LLGL2.
IPR001388. Synaptobrevin.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF08596. Lgl_C. 1 hit.
PF08366. LLGL. 1 hit.
PF00400. WD40. 2 hits.
[Graphical view]
PRINTSiPR00962. LETHAL2GIANT.
SMARTiSM00320. WD40. 7 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 5 hits.
PROSITEiPS50892. V_SNARE. 1 hit.
PS00678. WD_REPEATS_1. 2 hits.
PS50082. WD_REPEATS_2. 1 hit.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3Z079-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRKFNIRKVL DGLTAGSSSA SQQQQQQQHP PGNREPEIQE TLQSEHFQLC
60 70 80 90 100
KTVRHGFPYQ PSALAFDPVQ KILAVGTQTG ALRLFGRPGV ECYCQHDSGA
110 120 130 140 150
AVIQLQFLIN EGALVSALAD DTLHLWNLRQ KRPAVLHSLK FCRERVTFCH
160 170 180 190 200
LPFQSKWLYV GTERGNIHIV NVESFTLSGY VIMWNKAIEL SSKAHPGPVV
210 220 230 240 250
HISDNPMDEG KLLIGFESGT VVLWDLKSKK ADYRYTYDEA IHSVAWHHEG
260 270 280 290 300
KQFICSHSDG TLTIWNVRSP AKPVQTITPH GKQLKDGKKP EPCKPILKVE
310 320 330 340 350
LKTTRSGEPF IILSGGLSYD TVGRRPCLTV MHGKSTAVLE MDYSIVDFLT
360 370 380 390 400
LCETPYPNDF QEPYAVVVLL EKDLVLIDLA QNGYPIFENP YPLSIHESPV
410 420 430 440 450
TCCEYFADCP VDLIPALYSV GARQKRQGYS KKEWPINGGN WGLGAQSYPE
460 470 480 490 500
IIITGHADGS VKFWDASAIT LQVLYKLKTS KVFEKSRNKD DRQNTDIVDE
510 520 530 540 550
DPYAIQIISW CPESRMLCIA GVSAHVIIYR FSKQEVLTEV IPMLEVRLLY
560 570 580 590 600
EINDVDTPEG EQPPPLSTPV GSSNPQPIPP QSHPSTSSSS SDGLRDNVPC
610 620 630 640 650
LKVKNSPLKQ SPGYQTELVI QLVWVGGEPP QQITSLALNS SYGLVVFGNC
660 670 680 690 700
NGIAMVDYLQ KAVLLNLSTI ELYGSNDPYR REPRSPRKSR QPSGAGLCDI
710 720 730 740 750
TEGTVVPEDR CKSPTSAKMS RKLSLPTDLK PDLDVKDNSF SRSRSSSVTS
760 770 780 790 800
IDKESRETIS ALHFCETLTR KADSSPSPCL WVGTTVGTAF VITLNLPPGP
810 820 830 840 850
EQRLLQPVIV SPSGTILRLK GAILRMAFLD ATGCLMSPAY EPWKEHNVAE
860 870 880 890 900
EKDEKEKLKK RRPVSVSPSS SQEISENQYA VICSEKQAKV MSLPTQSCAY
910 920 930 940 950
KQNITETSFV LRGDIVALSN SVCLACFCAN GHIMTFSLPS LRPLLDVYYL
960 970 980 990 1000
PLTNMRIART FCFANNGQAL YLVSPTEIQR LTYSQETCEN LQEMLGELFT
1010 1020 1030 1040 1050
PVETPEAPNR GFFKGLFGGG AQSLDREELF GESSSGKASR SLAQHIPGPG
1060 1070 1080 1090 1100
GIEGVKGAAS GVVGELARAR LALDERGQKL SDLEERTAAM MSSADSFSKH
1110
AHEMMLKYKD KKWYQF
Length:1,116
Mass (Da):123,602
Last modified:April 20, 2010 - v1
Checksum:iAB8E0C8C41693427
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC122390 Genomic DNA. No translation available.
RefSeqiNP_001074813.2. NM_001081344.2.
UniGeneiMm.331751.

Genome annotation databases

EnsembliENSMUST00000141722; ENSMUSP00000123253; ENSMUSG00000019790.
GeneIDi78808.
KEGGimmu:78808.
UCSCiuc007eiz.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC122390 Genomic DNA. No translation available.
RefSeqi NP_001074813.2. NM_001081344.2.
UniGenei Mm.331751.

3D structure databases

ProteinModelPortali D3Z079.
SMRi D3Z079. Positions 56-87, 194-268, 437-468, 505-532, 1052-1108.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi D3Z079.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000141722 ; ENSMUSP00000123253 ; ENSMUSG00000019790 .
GeneIDi 78808.
KEGGi mmu:78808.
UCSCi uc007eiz.2. mouse.

Organism-specific databases

CTDi 134957.
MGIi MGI:1926058. Stxbp5.

Phylogenomic databases

GeneTreei ENSGT00390000000018.
HOGENOMi HOG000110929.
KOi K08518.
TreeFami TF314585.

Miscellaneous databases

NextBioi 349566.
SOURCEi Search...

Gene expression databases

Bgeei D3Z079.
ExpressionAtlasi D3Z079. baseline and differential.

Family and domain databases

Gene3Di 2.130.10.10. 3 hits.
InterProi IPR000664. Lethal2_giant.
IPR013905. Lgl_C_dom.
IPR013577. LLGL2.
IPR001388. Synaptobrevin.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view ]
Pfami PF08596. Lgl_C. 1 hit.
PF08366. LLGL. 1 hit.
PF00400. WD40. 2 hits.
[Graphical view ]
PRINTSi PR00962. LETHAL2GIANT.
SMARTi SM00320. WD40. 7 hits.
[Graphical view ]
SUPFAMi SSF50978. SSF50978. 5 hits.
PROSITEi PS50892. V_SNARE. 1 hit.
PS00678. WD_REPEATS_1. 2 hits.
PS50082. WD_REPEATS_2. 1 hit.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
    Trinidad J.C., Specht C.G., Thalhammer A., Schoepfer R., Burlingame A.L.
    Mol. Cell. Proteomics 5:914-922(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. "The phagosomal proteome in interferon-gamma-activated macrophages."
    Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
    Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  5. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiD3Z079_MOUSE
AccessioniPrimary (citable) accession number: D3Z079
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: October 29, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3