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D3Z079

- D3Z079_MOUSE

UniProt

D3Z079 - D3Z079_MOUSE

Protein
Submitted name:

Syntaxin-binding protein 5

Gene

Stxbp5

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 39 (01 Oct 2014)
      Sequence version 1 (20 Apr 2010)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. protein binding Source: MGI
    2. syntaxin-1 binding Source: MGI
    3. syntaxin binding Source: MGI

    GO - Biological processi

    1. exocytosis Source: MGI
    2. regulation of exocytosis Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Syntaxin-binding protein 5Imported
    Gene namesi
    Name:Stxbp5Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 10

    Organism-specific databases

    MGIiMGI:1926058. Stxbp5.

    Subcellular locationi

    GO - Cellular componenti

    1. acetylcholine-gated channel complex Source: MGI

    PTM / Processingi

    Proteomic databases

    PRIDEiD3Z079.

    Expressioni

    Gene expression databases

    ArrayExpressiD3Z079.
    BgeeiD3Z079.

    Structurei

    3D structure databases

    ProteinModelPortaliD3Z079.
    SMRiD3Z079. Positions 1052-1108.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    RepeatUniRule annotation, WD repeatUniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00390000000018.
    HOGENOMiHOG000110929.
    KOiK08518.
    TreeFamiTF314585.

    Family and domain databases

    Gene3Di2.130.10.10. 3 hits.
    InterProiIPR000664. Lethal2_giant.
    IPR013905. Lgl_C_dom.
    IPR013577. LLGL2.
    IPR001388. Synaptobrevin.
    IPR015943. WD40/YVTN_repeat-like_dom.
    IPR001680. WD40_repeat.
    IPR019775. WD40_repeat_CS.
    IPR017986. WD40_repeat_dom.
    [Graphical view]
    PfamiPF08596. Lgl_C. 1 hit.
    PF08366. LLGL. 1 hit.
    PF00400. WD40. 2 hits.
    [Graphical view]
    PRINTSiPR00962. LETHAL2GIANT.
    SMARTiSM00320. WD40. 7 hits.
    [Graphical view]
    SUPFAMiSSF50978. SSF50978. 5 hits.
    PROSITEiPS50892. V_SNARE. 1 hit.
    PS00678. WD_REPEATS_1. 2 hits.
    PS50082. WD_REPEATS_2. 1 hit.
    PS50294. WD_REPEATS_REGION. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D3Z079-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRKFNIRKVL DGLTAGSSSA SQQQQQQQHP PGNREPEIQE TLQSEHFQLC     50
    KTVRHGFPYQ PSALAFDPVQ KILAVGTQTG ALRLFGRPGV ECYCQHDSGA 100
    AVIQLQFLIN EGALVSALAD DTLHLWNLRQ KRPAVLHSLK FCRERVTFCH 150
    LPFQSKWLYV GTERGNIHIV NVESFTLSGY VIMWNKAIEL SSKAHPGPVV 200
    HISDNPMDEG KLLIGFESGT VVLWDLKSKK ADYRYTYDEA IHSVAWHHEG 250
    KQFICSHSDG TLTIWNVRSP AKPVQTITPH GKQLKDGKKP EPCKPILKVE 300
    LKTTRSGEPF IILSGGLSYD TVGRRPCLTV MHGKSTAVLE MDYSIVDFLT 350
    LCETPYPNDF QEPYAVVVLL EKDLVLIDLA QNGYPIFENP YPLSIHESPV 400
    TCCEYFADCP VDLIPALYSV GARQKRQGYS KKEWPINGGN WGLGAQSYPE 450
    IIITGHADGS VKFWDASAIT LQVLYKLKTS KVFEKSRNKD DRQNTDIVDE 500
    DPYAIQIISW CPESRMLCIA GVSAHVIIYR FSKQEVLTEV IPMLEVRLLY 550
    EINDVDTPEG EQPPPLSTPV GSSNPQPIPP QSHPSTSSSS SDGLRDNVPC 600
    LKVKNSPLKQ SPGYQTELVI QLVWVGGEPP QQITSLALNS SYGLVVFGNC 650
    NGIAMVDYLQ KAVLLNLSTI ELYGSNDPYR REPRSPRKSR QPSGAGLCDI 700
    TEGTVVPEDR CKSPTSAKMS RKLSLPTDLK PDLDVKDNSF SRSRSSSVTS 750
    IDKESRETIS ALHFCETLTR KADSSPSPCL WVGTTVGTAF VITLNLPPGP 800
    EQRLLQPVIV SPSGTILRLK GAILRMAFLD ATGCLMSPAY EPWKEHNVAE 850
    EKDEKEKLKK RRPVSVSPSS SQEISENQYA VICSEKQAKV MSLPTQSCAY 900
    KQNITETSFV LRGDIVALSN SVCLACFCAN GHIMTFSLPS LRPLLDVYYL 950
    PLTNMRIART FCFANNGQAL YLVSPTEIQR LTYSQETCEN LQEMLGELFT 1000
    PVETPEAPNR GFFKGLFGGG AQSLDREELF GESSSGKASR SLAQHIPGPG 1050
    GIEGVKGAAS GVVGELARAR LALDERGQKL SDLEERTAAM MSSADSFSKH 1100
    AHEMMLKYKD KKWYQF 1116
    Length:1,116
    Mass (Da):123,602
    Last modified:April 20, 2010 - v1
    Checksum:iAB8E0C8C41693427
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC122390 Genomic DNA. No translation available.
    RefSeqiNP_001074813.2. NM_001081344.2.
    UniGeneiMm.331751.

    Genome annotation databases

    EnsembliENSMUST00000141722; ENSMUSP00000123253; ENSMUSG00000019790.
    GeneIDi78808.
    KEGGimmu:78808.
    UCSCiuc007eiz.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC122390 Genomic DNA. No translation available.
    RefSeqi NP_001074813.2. NM_001081344.2.
    UniGenei Mm.331751.

    3D structure databases

    ProteinModelPortali D3Z079.
    SMRi D3Z079. Positions 1052-1108.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi D3Z079.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000141722 ; ENSMUSP00000123253 ; ENSMUSG00000019790 .
    GeneIDi 78808.
    KEGGi mmu:78808.
    UCSCi uc007eiz.2. mouse.

    Organism-specific databases

    CTDi 134957.
    MGIi MGI:1926058. Stxbp5.

    Phylogenomic databases

    GeneTreei ENSGT00390000000018.
    HOGENOMi HOG000110929.
    KOi K08518.
    TreeFami TF314585.

    Miscellaneous databases

    NextBioi 349566.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi D3Z079.
    Bgeei D3Z079.

    Family and domain databases

    Gene3Di 2.130.10.10. 3 hits.
    InterProi IPR000664. Lethal2_giant.
    IPR013905. Lgl_C_dom.
    IPR013577. LLGL2.
    IPR001388. Synaptobrevin.
    IPR015943. WD40/YVTN_repeat-like_dom.
    IPR001680. WD40_repeat.
    IPR019775. WD40_repeat_CS.
    IPR017986. WD40_repeat_dom.
    [Graphical view ]
    Pfami PF08596. Lgl_C. 1 hit.
    PF08366. LLGL. 1 hit.
    PF00400. WD40. 2 hits.
    [Graphical view ]
    PRINTSi PR00962. LETHAL2GIANT.
    SMARTi SM00320. WD40. 7 hits.
    [Graphical view ]
    SUPFAMi SSF50978. SSF50978. 5 hits.
    PROSITEi PS50892. V_SNARE. 1 hit.
    PS00678. WD_REPEATS_1. 2 hits.
    PS50082. WD_REPEATS_2. 1 hit.
    PS50294. WD_REPEATS_REGION. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
      Trinidad J.C., Specht C.G., Thalhammer A., Schoepfer R., Burlingame A.L.
      Mol. Cell. Proteomics 5:914-922(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. "The phagosomal proteome in interferon-gamma-activated macrophages."
      Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
      Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    5. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiD3Z079_MOUSE
    AccessioniPrimary (citable) accession number: D3Z079
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 20, 2010
    Last sequence update: April 20, 2010
    Last modified: October 1, 2014
    This is version 39 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3