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D3YZU4 (D3YZU4_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
Name:Shank1 Ensembl ENSMUSP00000103568 MGI 3613677
OrganismMus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000103568
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length2159 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Contains 1 PDZ (DHR) domain.

Contains 6 ANK repeats. RuleBase RU003321

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000103568

Sequences

Sequence LengthMass (Da)Tools
D3YZU4 [UniParc].

Last modified April 20, 2010. Version 1.
Checksum: 78EA8FD9E436C06F

FASTA2,159225,350
        10         20         30         40         50         60 
MTHSPATSED EERHSASECP EGGSESDSSP DGPGRGPQGT RGRGSGAPGN LASTRGLQGR 

        70         80         90        100        110        120 
SMSVPDDAHF SMMVFRIGIP DLHQTKCLRF NPDATIWTAK QQVLCALSES LQDVLNYGLF 

       130        140        150        160        170        180 
QPATSGRDAN FLEEERLLRE YPQSFEKGVP YLEFRYKTRV YKQTNLDEKQ LAKLHTKTGL 

       190        200        210        220        230        240 
KKFLEYVQLG TSDKVARLLD KGLDPNYHDS DSGETPLTLA AQTEGSVEVI RTLCLGGAHI 

       250        260        270        280        290        300 
DFRARDGMTA LHKAACARHC LALTALLDLG GSPNYKDRRG LTPLFHTAMV GGDPRCCELL 

       310        320        330        340        350        360 
LYNRAQLGIA DENGWQEIHQ ACQRGHSQHL EHLLFYGAEP GAQNASGNTA LHICALYNKE 

       370        380        390        400        410        420 
TCARILLYRG ANKDVKNNNG QTPFQVAVIA GNFELGELIR NHREQDVVPF QESPKYAARR 

       430        440        450        460        470        480 
RGPPGAGLTV PPALLRANSD TSMALPDWMV FSAPGASSSG TPGPTSGSQG QSQPSAPSTK 

       490        500        510        520        530        540 
LSSGTLRSAS SPRGARARSP SRGRHPEDAK RQPRGRPSSS GTPRDGPAGG TGGSGGPGGS 

       550        560        570        580        590        600 
LGSRGRRRKL YSAVPGRSFM AVKSYQAQGE GEISLSKGEK IKVLSIGEGG FWEGQVKGRV 

       610        620        630        640        650        660 
GWFPSDCLEE VANRSQEGRQ ESRSDKAKRL FRHYTVGSYD SFDAPSLIDG IDSGSDYIIK 

       670        680        690        700        710        720 
EKTVLLQKKD SEGFGFVLRG AKAQTPIEEF TPTPAFPALQ YLESVDEGGV AWRAGLRMGD 

       730        740        750        760        770        780 
FLIEVNGQNV VKVGHRQVVN MIRQGGNTLM VKVVMVTRHP DMDEAVHKKA SQQAKRLPPP 

       790        800        810        820        830        840 
AISLRSKSMT SELEEMEYEQ QPAAVPSMEK KRTVYQMALN KLDEILAAAQ QTISASESPG 

       850        860        870        880        890        900 
PGGLASLGKH RPKGFFATES SFDPHHRSQP SYDRPSFLPP GPGLMLRQKS IGAAEDDRPY 

       910        920        930        940        950        960 
LAPPAMKFSR SLSVPGSEDI PPPPTTSPPE PPYSTPPAPS SSGRLTPSPR GGPFNPGSGG 

       970        980        990       1000       1010       1020 
PLPASSPSSF DGPSPPDPRS GGREKSLYHS GALPPAHHHP PHHHHHHAPP PQPHHHHAHP 

      1030       1040       1050       1060       1070       1080 
PHPPEMETGG SPDDPPPRLA LGPQPSLRGW RGGGPSPTSG APSPSHHSSS GGSSGPAQAP 

      1090       1100       1110       1120       1130       1140 
ALRYFQLPPR AASAAMYVPA RSGRGRKGPL VKQTKVEGEP QKGSLPPASS PTSPALPRSE 

      1150       1160       1170       1180       1190       1200 
PPPAGPSEKN SIPIPTIIIK APSTSSSGRS SQGSSTEAEP PTQPDGAGGG GSSPSPAPAT 

      1210       1220       1230       1240       1250       1260 
SPVPPSPSPV PTPASPSGPA TLDFTSQFGA ALVGAARREG GWQNEARRRS TLFLSTDAGD 

      1270       1280       1290       1300       1310       1320 
EDGGDSGLGP GAPPGPRLRH SKSIDEGMFS AEPYLRLESG GSSGGYGAYA AGSRAYGGSG 

      1330       1340       1350       1360       1370       1380 
SSSAFTSFLP PRPLVHPLTG KALDPASPLG LALAARERAL KESSEGGVTP QPPPRPPSPR 

      1390       1400       1410       1420       1430       1440 
YDAPPPTLHH HSPHSPHSPH ARHEPVLRLW GDPARRELGY RAGLGSQEKA LTASPPAARR 

      1450       1460       1470       1480       1490       1500 
SLLHRLPPTA PGVGPLLLQL GPEPPTPHPG VSKAWRTAAP EEPERLPLHV RFLENCQARP 

      1510       1520       1530       1540       1550       1560 
PPAGTRGSST EDGPGVPPPS PRRVLPTSPT SPRGNEENGL PLLVLPPPAP SVDVDDGEFL 

      1570       1580       1590       1600       1610       1620 
FAEPLPPPLE FSNSFEKPES PLTPGPPHPL PDPPSPATPL PAAPPPAVAA APPTLDSTAS 

      1630       1640       1650       1660       1670       1680 
SLTSYDSEVA TLTQGAPAAP GDPPAPGPPA PAAPAPPAPQ PGPDPPPGTD SGIEEVDSRS 

      1690       1700       1710       1720       1730       1740 
SSDHPLETIS SASTLSSLSA EGGGNTGGVA GGGAGVASGT ELLDTYVAYL DGQAFGGSGT 

      1750       1760       1770       1780       1790       1800 
PGPPYPPQLM TPSKLRGRAL GTSGNLRPGP SGGLRDPVTP TSPTVSVTGA GTDGLLALSA 

      1810       1820       1830       1840       1850       1860 
CSGPSTAGVA GGPVAVEPEV PPVPLPTASS LPRKLLPWEE GPGPPPPPLP GPLSQPQASA 

      1870       1880       1890       1900       1910       1920 
LATVKASIIS ELSSKLQQFG GASTAGGALP WARGGSGGST DSHHGGASYI PERTSSLQRQ 

      1930       1940       1950       1960       1970       1980 
RLSEDSQTSL LSKPSSSIFQ NWPKPPLPPL PTGSGVSSST AAAPGATSPS ASSASASTRH 

      1990       2000       2010       2020       2030       2040 
LQGVEFEMRP PLLRRAPSPS LLPASDHKVS PAPRPSSLPI LPSGPLYPGL FDIRSSPTGG 

      2050       2060       2070       2080       2090       2100 
AGGSADPFAP VFVPPHPGIS GGLGGALSGA SRSLSPTRLL SLPPDKPFGA KPLGFWTKFD 

      2110       2120       2130       2140       2150 
VADWLEWLGL SEHRAQFLDH EIDGSHLPAL TKEDYVDLGV TRVGHRMNID RALKFFLER 

« Hide

References

« Hide 'large scale' references
[1]"Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
Trinidad J.C., Specht C.G., Thalhammer A., Schoepfer R., Burlingame A.L.
Mol. Cell. Proteomics 5:914-922(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[2]"Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain."
Ballif B.A., Carey G.R., Sunyaev S.R., Gygi S.P.
J. Proteome Res. 7:311-318(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[3]"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. expand/collapse author list , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.
PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C57BL/6J Ensembl ENSMUSP00000103568.
[4]Ensembl
Submitted (MAY-2011) to UniProtKB
Cited for: IDENTIFICATION.
Strain: C57BL/6J Ensembl ENSMUSP00000103568.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC152939 Genomic DNA. No translation available.
RefSeqXP_006540928.1. XM_006540865.1.
UniGeneMm.360368.

3D structure databases

ProteinModelPortalD3YZU4.
SMRD3YZU4. Positions 656-759, 2093-2154.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActD3YZU4. 2 interactions.
MINTMINT-7894200.

Proteomic databases

PRIDED3YZU4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000107935; ENSMUSP00000103568; ENSMUSG00000038738.
GeneID243961.
KEGGmmu:243961.

Organism-specific databases

CTD50944.
MGIMGI:3613677. Shank1.

Phylogenomic databases

GeneTreeENSGT00510000046474.
HOGENOMHOG000293276.
KOK15009.

Gene expression databases

ArrayExpressD3YZU4.
BgeeD3YZU4.

Family and domain databases

Gene3D1.10.150.50. 1 hit.
1.25.40.20. 1 hit.
2.30.42.10. 1 hit.
InterProIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR001478. PDZ.
IPR001660. SAM.
IPR013761. SAM/pointed.
IPR021129. SAM_type1.
IPR011511. SH3_2.
IPR001452. SH3_domain.
[Graphical view]
PfamPF12796. Ank_2. 2 hits.
PF00595. PDZ. 1 hit.
PF00536. SAM_1. 1 hit.
PF07653. SH3_2. 1 hit.
[Graphical view]
SMARTSM00248. ANK. 6 hits.
SM00228. PDZ. 1 hit.
SM00454. SAM. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMSSF47769. SSF47769. 1 hit.
SSF48403. SSF48403. 1 hit.
SSF50044. SSF50044. 1 hit.
SSF50156. SSF50156. 1 hit.
PROSITEPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 3 hits.
PS50106. PDZ. 1 hit.
PS50105. SAM_DOMAIN. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio35549888.
SOURCESearch...

Entry information

Entry nameD3YZU4_MOUSE
AccessionPrimary (citable) accession number: D3YZU4
Entry history
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: June 11, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)