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D3YZK4

- D3YZK4_MOUSE

UniProt

D3YZK4 - D3YZK4_MOUSE

Protein
Submitted name:

Transcription initiation factor TFIID subunit 1

Gene

Taf1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 35 (01 Oct 2014)
      Sequence version 1 (20 Apr 2010)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. DNA binding Source: MGI
    2. protein binding Source: MGI

    GO - Biological processi

    1. DNA-templated transcription, initiation Source: InterPro
    2. regulation of transcription, DNA-templated Source: InterPro
    3. response to drug Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Transcription initiation factor TFIID subunit 1Imported
    Gene namesi
    Name:Taf1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome X

    Organism-specific databases

    MGIiMGI:1336878. Taf1.

    Subcellular locationi

    GO - Cellular componenti

    1. nucleus Source: MGI
    2. pronucleus Source: MGI
    3. transcription factor TFIID complex Source: MGI

    PTM / Processingi

    Proteomic databases

    PRIDEiD3YZK4.

    Expressioni

    Gene expression databases

    BgeeiD3YZK4.

    Structurei

    3D structure databases

    ProteinModelPortaliD3YZK4.
    SMRiD3YZK4. Positions 1391-1657.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    BromodomainSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00390000012659.
    HOGENOMiHOG000020066.
    OMAiDEFYYPK.
    PhylomeDBiD3YZK4.
    TreeFamiTF313573.

    Family and domain databases

    Gene3Di1.10.1100.10. 1 hit.
    1.20.920.10. 2 hits.
    InterProiIPR001487. Bromodomain.
    IPR018359. Bromodomain_CS.
    IPR011177. TAF1_animal.
    IPR009067. TAF_II_230-bd.
    IPR022591. TFIID_sub1_DUF3591.
    [Graphical view]
    PfamiPF00439. Bromodomain. 2 hits.
    PF12157. DUF3591. 1 hit.
    PF09247. TBP-binding. 1 hit.
    [Graphical view]
    PIRSFiPIRSF003047. TAF1_animal. 1 hit.
    PRINTSiPR00503. BROMODOMAIN.
    SMARTiSM00297. BROMO. 2 hits.
    [Graphical view]
    SUPFAMiSSF47055. SSF47055. 1 hit.
    SSF47370. SSF47370. 2 hits.
    PROSITEiPS00633. BROMODOMAIN_1. 2 hits.
    PS50014. BROMODOMAIN_2. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D3YZK4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGPGWAGLLQ DKGGGSPSVV MSDTDSDEES AGGGPFSLTG FLFGNINGAG     50
    QLEGESVLDD ECKKHLAGLG ALGLGSLITE LTANEELSGS DGALVNDEGW 100
    IRSREDAVDY SDINEVAEDE SRRYQQTMGS LQPLCHTDYD EDDYDADCED 150
    IDCKLMPPPP PPPGPLKKEK DQDDITGEKV DFSSSSDSES EMGPQDAAQS 200
    ESKDGQLTLP LAGIMQHDAT KLLPSVTELF PEFRPGKVLR FLRLFGPGKN 250
    VPSVWRSARR KRKKKHRELI QEGQVQEEEC SVELEVNQKS LWNYDYAPPP 300
    LPDQCLSDDE ITMMAPVESK FSQSTGDTDK VMDTKPRVAE WRYGPARLWY 350
    DMLGVPEDGS GFDYGFKMKK TEHESTIKCN IMKKLRKLEE NSGVDLLADE 400
    NFLMVTQLHW EDDIIWDGED VKHKGTKPQR ASLAGWLPSS MTRNAMAYNV 450
    QQGRPCIKKP TSQTKQNTHT QNSISQPSGS LHTTLDDDKP WYSIFPIDNE 500
    DLVYGRWEDN IIWDAQNMPR ILEPPVLTLD PNDENLILEI PDEKEEATSN 550
    SPSKENKKES SLKKSRILLG KTGVIKEEPQ QNMSQPEVKD PWNLSNDEYY 600
    YPKQQGLRGT FGGNIIQHSI PAVELRQPFF PTHMGPIKLR QFHRPPLKKY 650
    SFGALSQPGP HSVQPLLKHI KKKAKMREQE RQASGGGEMF FMRTPQDLTG 700
    KDGDLILAEY SEENGPLMMQ VGMATKIKNY YKRKPGKDPG APDCKYGETV 750
    YCHTSPFLGS LHPGQLLQAF ENNLFRAPIY LHKMPESDFL IIRTRQGYFI 800
    RELVDIFVVG QQCPLFEVPG PNSKRANTHI RDFLQVFIYR LFWKSKDRPR 850
    RIRMEDIKKA FPSHSESSIR KRLKLCADFK RTGMDSNWWV LKSDFRLPTE 900
    EEIRAMVSPE QCCAYYSMIA AEQRLKDAGY GEKSFFAPEE ENEEDFQMKI 950
    DDEVRTAPWN TTRAFIAAMK GKCLLEVTGV ADPTGCGEGF SYVKIPNKPT 1000
    QQKDDKEPQP VKKTVTGTDA DLRRLSLKNA KQLLRKFGVP EEEIKKLSRW 1050
    EVIDVVRTMS TEQARSGEGP MSKFARGSRF SVAEHQERYK EECQRIFDLQ 1100
    NKVLSSTEVL STDTDSSSAE DSDFEEMGKN IENMLQNKKT SSQLSREREE 1150
    QERKELQRML LEADGEAAGS AAAGNNHRDD DTASVTSLNS SATGRCLKIY 1200
    RTFRDEEGKE YVRCETVRKA TVIDAYVRIR TTKDEEFIRK FALFDEQHRE 1250
    EMRKERRRIQ EQLRRLKRNQ EKEKLKGPPE KKPKKMKERP DLKLKCGACG 1300
    AIGHMRTNKF CPLYYQTNAP PSNPVAMTEE QEEELEKTVI HNDNEELIKV 1350
    EGTKIVLGKQ LIESADEVRR KSLVLKFPKQ QLPPKKKRRV GTTVHCDYLN 1400
    RPHKSIHRRR TDPMVTLSSI LESIINDMRD LPNTYPFHTP VNAKVVKDYY 1450
    KIITRPMDLQ TLRENVRKRL YPSREEFREH LELIVKNSAT YNGPKHSLTQ 1500
    ISQSMLDLCD EKLKEKEDKL ARLEKAINPL LDDDDQVAFS FILDNIVTQK 1550
    MMAVPDSWPF HHPVNKKFVP DYYKVIVSPM DLETIRKNIS KHKYQSRESF 1600
    LDDVNLILAN SVKYNGPESQ YTKTAQEIVN VCHQTLTEYD EHLTQLEKDI 1650
    CTAKEAALEE AELESLDPMT PGPYTPQPPD LYDNNTSLSV SRDASVYQDE 1700
    SNLSVLDIPS ATSEKQLTQE GGDGDGDLAD EEEGTVQQPQ ASVLYEDLLM 1750
    SEGEDDEEDA GSDEEGDNPF FAIQLSESGS DSDVESGSLR PKQPRVLQEN 1800
    TRMGMENEES MMSYEGDGGD ASRGLEDSNI SYGSYEEPDP KSNTQDTSFS 1850
    SIGGYEVSEE EEDEEEQRSG PSVLSQVHLS EDEEDSEDFH SIAGDTDLDS 1900
    DE 1902
    Length:1,902
    Mass (Da):215,852
    Last modified:April 20, 2010 - v1
    Checksum:i082A891374BEABDE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL806534 Genomic DNA. No translation available.
    AL831722 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000101341; ENSMUSP00000098895; ENSMUSG00000031314.
    UCSCiuc009txw.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL806534 Genomic DNA. No translation available.
    AL831722 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali D3YZK4.
    SMRi D3YZK4. Positions 1391-1657.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi D3YZK4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000101341 ; ENSMUSP00000098895 ; ENSMUSG00000031314 .
    UCSCi uc009txw.1. mouse.

    Organism-specific databases

    MGIi MGI:1336878. Taf1.

    Phylogenomic databases

    GeneTreei ENSGT00390000012659.
    HOGENOMi HOG000020066.
    OMAi DEFYYPK.
    PhylomeDBi D3YZK4.
    TreeFami TF313573.

    Miscellaneous databases

    NextBioi 393355.
    SOURCEi Search...

    Gene expression databases

    Bgeei D3YZK4.

    Family and domain databases

    Gene3Di 1.10.1100.10. 1 hit.
    1.20.920.10. 2 hits.
    InterProi IPR001487. Bromodomain.
    IPR018359. Bromodomain_CS.
    IPR011177. TAF1_animal.
    IPR009067. TAF_II_230-bd.
    IPR022591. TFIID_sub1_DUF3591.
    [Graphical view ]
    Pfami PF00439. Bromodomain. 2 hits.
    PF12157. DUF3591. 1 hit.
    PF09247. TBP-binding. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF003047. TAF1_animal. 1 hit.
    PRINTSi PR00503. BROMODOMAIN.
    SMARTi SM00297. BROMO. 2 hits.
    [Graphical view ]
    SUPFAMi SSF47055. SSF47055. 1 hit.
    SSF47370. SSF47370. 2 hits.
    PROSITEi PS00633. BROMODOMAIN_1. 2 hits.
    PS50014. BROMODOMAIN_2. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The phagosomal proteome in interferon-gamma-activated macrophages."
      Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
      Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    3. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.
    4. "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.
      Mol. Cell 50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiD3YZK4_MOUSE
    AccessioniPrimary (citable) accession number: D3YZK4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 20, 2010
    Last sequence update: April 20, 2010
    Last modified: October 1, 2014
    This is version 35 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3