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D3YZK4

- D3YZK4_MOUSE

UniProt

D3YZK4 - D3YZK4_MOUSE

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Protein
Submitted name:

Transcription initiation factor TFIID subunit 1

Gene

Taf1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. DNA binding Source: MGI

GO - Biological processi

  1. DNA-templated transcription, initiation Source: InterPro
  2. regulation of transcription, DNA-templated Source: InterPro
  3. response to drug Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Transcription initiation factor TFIID subunit 1Imported
Gene namesi
Name:Taf1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome X

Organism-specific databases

MGIiMGI:1336878. Taf1.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: MGI
  2. pronucleus Source: MGI
  3. transcription factor TFIID complex Source: MGI
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiD3YZK4.

Expressioni

Gene expression databases

BgeeiD3YZK4.
ExpressionAtlasiD3YZK4. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliD3YZK4.
SMRiD3YZK4. Positions 1391-1657.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

BromodomainSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00390000012659.
HOGENOMiHOG000020066.
OMAiDEFYYPK.
PhylomeDBiD3YZK4.
TreeFamiTF313573.

Family and domain databases

Gene3Di1.10.1100.10. 1 hit.
1.20.920.10. 2 hits.
InterProiIPR001487. Bromodomain.
IPR018359. Bromodomain_CS.
IPR011177. TAF1_animal.
IPR009067. TAF_II_230-bd.
IPR022591. TFIID_sub1_DUF3591.
[Graphical view]
PfamiPF00439. Bromodomain. 2 hits.
PF12157. DUF3591. 1 hit.
PF09247. TBP-binding. 1 hit.
[Graphical view]
PIRSFiPIRSF003047. TAF1_animal. 1 hit.
PRINTSiPR00503. BROMODOMAIN.
SMARTiSM00297. BROMO. 2 hits.
[Graphical view]
SUPFAMiSSF47055. SSF47055. 1 hit.
SSF47370. SSF47370. 2 hits.
PROSITEiPS00633. BROMODOMAIN_1. 2 hits.
PS50014. BROMODOMAIN_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3YZK4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGPGWAGLLQ DKGGGSPSVV MSDTDSDEES AGGGPFSLTG FLFGNINGAG
60 70 80 90 100
QLEGESVLDD ECKKHLAGLG ALGLGSLITE LTANEELSGS DGALVNDEGW
110 120 130 140 150
IRSREDAVDY SDINEVAEDE SRRYQQTMGS LQPLCHTDYD EDDYDADCED
160 170 180 190 200
IDCKLMPPPP PPPGPLKKEK DQDDITGEKV DFSSSSDSES EMGPQDAAQS
210 220 230 240 250
ESKDGQLTLP LAGIMQHDAT KLLPSVTELF PEFRPGKVLR FLRLFGPGKN
260 270 280 290 300
VPSVWRSARR KRKKKHRELI QEGQVQEEEC SVELEVNQKS LWNYDYAPPP
310 320 330 340 350
LPDQCLSDDE ITMMAPVESK FSQSTGDTDK VMDTKPRVAE WRYGPARLWY
360 370 380 390 400
DMLGVPEDGS GFDYGFKMKK TEHESTIKCN IMKKLRKLEE NSGVDLLADE
410 420 430 440 450
NFLMVTQLHW EDDIIWDGED VKHKGTKPQR ASLAGWLPSS MTRNAMAYNV
460 470 480 490 500
QQGRPCIKKP TSQTKQNTHT QNSISQPSGS LHTTLDDDKP WYSIFPIDNE
510 520 530 540 550
DLVYGRWEDN IIWDAQNMPR ILEPPVLTLD PNDENLILEI PDEKEEATSN
560 570 580 590 600
SPSKENKKES SLKKSRILLG KTGVIKEEPQ QNMSQPEVKD PWNLSNDEYY
610 620 630 640 650
YPKQQGLRGT FGGNIIQHSI PAVELRQPFF PTHMGPIKLR QFHRPPLKKY
660 670 680 690 700
SFGALSQPGP HSVQPLLKHI KKKAKMREQE RQASGGGEMF FMRTPQDLTG
710 720 730 740 750
KDGDLILAEY SEENGPLMMQ VGMATKIKNY YKRKPGKDPG APDCKYGETV
760 770 780 790 800
YCHTSPFLGS LHPGQLLQAF ENNLFRAPIY LHKMPESDFL IIRTRQGYFI
810 820 830 840 850
RELVDIFVVG QQCPLFEVPG PNSKRANTHI RDFLQVFIYR LFWKSKDRPR
860 870 880 890 900
RIRMEDIKKA FPSHSESSIR KRLKLCADFK RTGMDSNWWV LKSDFRLPTE
910 920 930 940 950
EEIRAMVSPE QCCAYYSMIA AEQRLKDAGY GEKSFFAPEE ENEEDFQMKI
960 970 980 990 1000
DDEVRTAPWN TTRAFIAAMK GKCLLEVTGV ADPTGCGEGF SYVKIPNKPT
1010 1020 1030 1040 1050
QQKDDKEPQP VKKTVTGTDA DLRRLSLKNA KQLLRKFGVP EEEIKKLSRW
1060 1070 1080 1090 1100
EVIDVVRTMS TEQARSGEGP MSKFARGSRF SVAEHQERYK EECQRIFDLQ
1110 1120 1130 1140 1150
NKVLSSTEVL STDTDSSSAE DSDFEEMGKN IENMLQNKKT SSQLSREREE
1160 1170 1180 1190 1200
QERKELQRML LEADGEAAGS AAAGNNHRDD DTASVTSLNS SATGRCLKIY
1210 1220 1230 1240 1250
RTFRDEEGKE YVRCETVRKA TVIDAYVRIR TTKDEEFIRK FALFDEQHRE
1260 1270 1280 1290 1300
EMRKERRRIQ EQLRRLKRNQ EKEKLKGPPE KKPKKMKERP DLKLKCGACG
1310 1320 1330 1340 1350
AIGHMRTNKF CPLYYQTNAP PSNPVAMTEE QEEELEKTVI HNDNEELIKV
1360 1370 1380 1390 1400
EGTKIVLGKQ LIESADEVRR KSLVLKFPKQ QLPPKKKRRV GTTVHCDYLN
1410 1420 1430 1440 1450
RPHKSIHRRR TDPMVTLSSI LESIINDMRD LPNTYPFHTP VNAKVVKDYY
1460 1470 1480 1490 1500
KIITRPMDLQ TLRENVRKRL YPSREEFREH LELIVKNSAT YNGPKHSLTQ
1510 1520 1530 1540 1550
ISQSMLDLCD EKLKEKEDKL ARLEKAINPL LDDDDQVAFS FILDNIVTQK
1560 1570 1580 1590 1600
MMAVPDSWPF HHPVNKKFVP DYYKVIVSPM DLETIRKNIS KHKYQSRESF
1610 1620 1630 1640 1650
LDDVNLILAN SVKYNGPESQ YTKTAQEIVN VCHQTLTEYD EHLTQLEKDI
1660 1670 1680 1690 1700
CTAKEAALEE AELESLDPMT PGPYTPQPPD LYDNNTSLSV SRDASVYQDE
1710 1720 1730 1740 1750
SNLSVLDIPS ATSEKQLTQE GGDGDGDLAD EEEGTVQQPQ ASVLYEDLLM
1760 1770 1780 1790 1800
SEGEDDEEDA GSDEEGDNPF FAIQLSESGS DSDVESGSLR PKQPRVLQEN
1810 1820 1830 1840 1850
TRMGMENEES MMSYEGDGGD ASRGLEDSNI SYGSYEEPDP KSNTQDTSFS
1860 1870 1880 1890 1900
SIGGYEVSEE EEDEEEQRSG PSVLSQVHLS EDEEDSEDFH SIAGDTDLDS

DE
Length:1,902
Mass (Da):215,852
Last modified:April 20, 2010 - v1
Checksum:i082A891374BEABDE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL806534 Genomic DNA. No translation available.
AL831722 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000101341; ENSMUSP00000098895; ENSMUSG00000031314.
UCSCiuc009txw.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL806534 Genomic DNA. No translation available.
AL831722 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali D3YZK4.
SMRi D3YZK4. Positions 1391-1657.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi D3YZK4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000101341 ; ENSMUSP00000098895 ; ENSMUSG00000031314 .
UCSCi uc009txw.1. mouse.

Organism-specific databases

MGIi MGI:1336878. Taf1.

Phylogenomic databases

GeneTreei ENSGT00390000012659.
HOGENOMi HOG000020066.
OMAi DEFYYPK.
PhylomeDBi D3YZK4.
TreeFami TF313573.

Miscellaneous databases

NextBioi 393355.
SOURCEi Search...

Gene expression databases

Bgeei D3YZK4.
ExpressionAtlasi D3YZK4. baseline and differential.

Family and domain databases

Gene3Di 1.10.1100.10. 1 hit.
1.20.920.10. 2 hits.
InterProi IPR001487. Bromodomain.
IPR018359. Bromodomain_CS.
IPR011177. TAF1_animal.
IPR009067. TAF_II_230-bd.
IPR022591. TFIID_sub1_DUF3591.
[Graphical view ]
Pfami PF00439. Bromodomain. 2 hits.
PF12157. DUF3591. 1 hit.
PF09247. TBP-binding. 1 hit.
[Graphical view ]
PIRSFi PIRSF003047. TAF1_animal. 1 hit.
PRINTSi PR00503. BROMODOMAIN.
SMARTi SM00297. BROMO. 2 hits.
[Graphical view ]
SUPFAMi SSF47055. SSF47055. 1 hit.
SSF47370. SSF47370. 2 hits.
PROSITEi PS00633. BROMODOMAIN_1. 2 hits.
PS50014. BROMODOMAIN_2. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The phagosomal proteome in interferon-gamma-activated macrophages."
    Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
    Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.
  4. "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
    Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.
    Mol. Cell 50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiD3YZK4_MOUSE
AccessioniPrimary (citable) accession number: D3YZK4
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: October 29, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3