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Protein
Submitted name:

Natural resistance-associated macrophage protein 2

Gene

Slc11a2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

  • activation of cysteine-type endopeptidase activity involved in apoptotic process Source: MGI
  • cadmium ion transmembrane transport Source: MGI
  • cation transmembrane transport Source: MGI
  • cellular copper ion homeostasis Source: Ensembl
  • cellular response to hypoxia Source: Ensembl
  • cellular response to iron ion Source: Ensembl
  • cellular response to oxidative stress Source: MGI
  • cellular response to tumor necrosis factor Source: Ensembl
  • cobalt ion transport Source: MGI
  • copper ion import into cell Source: Ensembl
  • copper ion transmembrane transport Source: MGI
  • copper ion transport Source: MGI
  • dendrite morphogenesis Source: MGI
  • detection of oxygen Source: Ensembl
  • erythrocyte development Source: MGI
  • ferrous iron import Source: MGI
  • ferrous iron transmembrane transport Source: MGI
  • ferrous iron transport Source: MGI
  • heme biosynthetic process Source: MGI
  • hydrogen ion transmembrane transport Source: GOC
  • iron ion transport Source: MGI
  • lead ion transport Source: MGI
  • learning or memory Source: MGI
  • manganese ion transmembrane transport Source: MGI
  • manganese ion transport Source: MGI
  • multicellular organismal iron ion homeostasis Source: MGI
  • nickel cation transmembrane transport Source: MGI
  • nickel cation transport Source: MGI
  • porphyrin-containing compound biosynthetic process Source: MGI
  • porphyrin-containing compound metabolic process Source: MGI
  • proton transport Source: MGI
  • response to cadmium ion Source: Ensembl
  • response to lead ion Source: Ensembl
  • response to manganese ion Source: Ensembl
  • vanadium ion transport Source: MGI
  • zinc II ion transmembrane transport Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Natural resistance-associated macrophage protein 2Imported
Gene namesi
Name:Slc11a2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 15

Organism-specific databases

MGIiMGI:1345279. Slc11a2.

Subcellular locationi

GO - Cellular componenti

  • apical part of cell Source: MGI
  • apical plasma membrane Source: MGI
  • basal part of cell Source: MGI
  • brush border Source: MGI
  • cell surface Source: MGI
  • cytoplasm Source: MGI
  • cytoplasmic vesicle Source: MGI
  • early endosome Source: MGI
  • endomembrane system Source: MGI
  • endosome Source: MGI
  • integral component of plasma membrane Source: MGI
  • late endosome Source: MGI
  • late endosome membrane Source: MGI
  • lysosomal membrane Source: MGI
  • lysosome Source: MGI
  • membrane Source: MGI
  • nucleus Source: MGI
  • paraferritin complex Source: MGI
  • perinuclear region of cytoplasm Source: MGI
  • plasma membrane Source: MGI
  • recycling endosome Source: MGI
  • trans-Golgi network Source: MGI
  • vacuole Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiD3YXP3.
ExpressionAtlasiD3YXP3. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000023774.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000006526.

Sequencei

Sequence statusi: Fragment.

D3YXP3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLDPKEKMP DDGASGDHGD SASLGAINPA YSNSSLPHST GDSEEPFTTY
Length:50
Mass (Da):5,198
Last modified:April 20, 2010 - v1
Checksum:i1653383F7A5A3C2D
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei50 – 501Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC139571 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000154676; ENSMUSP00000115019; ENSMUSG00000023030.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC139571 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000023774.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000154676; ENSMUSP00000115019; ENSMUSG00000023030.

Organism-specific databases

MGIiMGI:1345279. Slc11a2.

Phylogenomic databases

GeneTreeiENSGT00390000006526.

Miscellaneous databases

ChiTaRSiSlc11a2. mouse.
NextBioi35549352.
SOURCEiSearch...

Gene expression databases

BgeeiD3YXP3.
ExpressionAtlasiD3YXP3. baseline and differential.

Family and domain databases

ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiD3YXP3_MOUSE
AccessioniPrimary (citable) accession number: D3YXP3
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: June 24, 2015
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.