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Protein
Submitted name:

Natural resistance-associated macrophage protein 2

Gene

Slc11a2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. cadmium ion binding Source: Ensembl
  2. cadmium ion transmembrane transporter activity Source: MGI
  3. cobalt ion binding Source: Ensembl
  4. cobalt ion transmembrane transporter activity Source: MGI
  5. copper ion binding Source: Ensembl
  6. copper ion transmembrane transporter activity Source: MGI
  7. ferrous iron transmembrane transporter activity Source: MGI
  8. hydrogen ion transmembrane transporter activity Source: MGI
  9. inorganic cation transmembrane transporter activity Source: MGI
  10. iron ion binding Source: Ensembl
  11. iron ion transmembrane transporter activity Source: MGI
  12. lead ion transmembrane transporter activity Source: MGI
  13. manganese ion binding Source: Ensembl
  14. manganese ion transmembrane transporter activity Source: MGI
  15. nickel cation binding Source: Ensembl
  16. nickel cation transmembrane transporter activity Source: MGI
  17. solute:proton symporter activity Source: MGI
  18. vanadium ion transmembrane transporter activity Source: MGI
  19. zinc ion binding Source: Ensembl
  20. zinc ion transmembrane transporter activity Source: Ensembl

GO - Biological processi

  1. activation of cysteine-type endopeptidase activity involved in apoptotic process Source: MGI
  2. cadmium ion transmembrane transport Source: MGI
  3. cation transmembrane transport Source: MGI
  4. cellular copper ion homeostasis Source: Ensembl
  5. cellular response to hypoxia Source: Ensembl
  6. cellular response to iron ion Source: Ensembl
  7. cellular response to oxidative stress Source: MGI
  8. cellular response to tumor necrosis factor Source: Ensembl
  9. cobalt ion transport Source: MGI
  10. copper ion import into cell Source: Ensembl
  11. copper ion transmembrane transport Source: MGI
  12. copper ion transport Source: MGI
  13. dendrite morphogenesis Source: MGI
  14. detection of oxygen Source: Ensembl
  15. erythrocyte development Source: MGI
  16. ferrous iron import Source: MGI
  17. ferrous iron transport Source: MGI
  18. heme biosynthetic process Source: MGI
  19. hydrogen ion transmembrane transport Source: GOC
  20. iron ion transmembrane transport Source: GOC
  21. iron ion transport Source: MGI
  22. lead ion transport Source: MGI
  23. learning or memory Source: MGI
  24. manganese ion transmembrane transport Source: MGI
  25. manganese ion transport Source: MGI
  26. multicellular organismal iron ion homeostasis Source: MGI
  27. nickel cation transmembrane transport Source: MGI
  28. nickel cation transport Source: MGI
  29. porphyrin-containing compound biosynthetic process Source: MGI
  30. porphyrin-containing compound metabolic process Source: MGI
  31. proton transport Source: MGI
  32. response to cadmium ion Source: Ensembl
  33. response to lead ion Source: Ensembl
  34. response to manganese ion Source: Ensembl
  35. vanadium ion transport Source: MGI
  36. zinc ion transmembrane transport Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Natural resistance-associated macrophage protein 2Imported
Gene namesi
Name:Slc11a2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 15

Organism-specific databases

MGIiMGI:1345279. Slc11a2.

Subcellular locationi

GO - Cellular componenti

  1. apical part of cell Source: MGI
  2. apical plasma membrane Source: MGI
  3. basal part of cell Source: MGI
  4. brush border Source: MGI
  5. cell surface Source: MGI
  6. cytoplasm Source: MGI
  7. cytoplasmic vesicle Source: MGI
  8. early endosome Source: MGI
  9. endomembrane system Source: MGI
  10. endosome Source: MGI
  11. integral component of plasma membrane Source: MGI
  12. late endosome Source: MGI
  13. late endosome membrane Source: MGI
  14. lysosomal membrane Source: MGI
  15. lysosome Source: MGI
  16. membrane Source: MGI
  17. nucleus Source: MGI
  18. paraferritin complex Source: MGI
  19. perinuclear region of cytoplasm Source: MGI
  20. plasma membrane Source: MGI
  21. recycling endosome Source: MGI
  22. trans-Golgi network Source: MGI
  23. vacuole Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiD3YXP3.
ExpressionAtlasiD3YXP3. baseline and differential.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000006526.

Sequencei

Sequence statusi: Fragment.

D3YXP3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLDPKEKMP DDGASGDHGD SASLGAINPA YSNSSLPHST GDSEEPFTTY
Length:50
Mass (Da):5,198
Last modified:April 20, 2010 - v1
Checksum:i1653383F7A5A3C2D
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei50 – 501Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC139571 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000154676; ENSMUSP00000115019; ENSMUSG00000023030.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC139571 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000154676; ENSMUSP00000115019; ENSMUSG00000023030.

Organism-specific databases

MGIiMGI:1345279. Slc11a2.

Phylogenomic databases

GeneTreeiENSGT00390000006526.

Miscellaneous databases

ChiTaRSiSlc11a2. mouse.
NextBioi35549352.
SOURCEiSearch...

Gene expression databases

BgeeiD3YXP3.
ExpressionAtlasiD3YXP3. baseline and differential.

Family and domain databases

ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiD3YXP3_MOUSE
AccessioniPrimary (citable) accession number: D3YXP3
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: February 4, 2015
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.