ID   D3YWU5_MOUSE            Unreviewed;        70 AA.
AC   D3YWU5;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 8.
DT   27-MAR-2024, entry version 90.
DE   SubName: Full=Insulin II {ECO:0000313|Ensembl:ENSMUSP00000115147.2};
DE   Flags: Fragment;
GN   Name=Ins2 {ECO:0000313|Ensembl:ENSMUSP00000115147.2,
GN   ECO:0000313|MGI:MGI:96573};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000115147.2, ECO:0000313|Proteomes:UP000000589};
RN   [1] {ECO:0000313|Ensembl:ENSMUSP00000115147.2, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000115147.2,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2] {ECO:0000313|Ensembl:ENSMUSP00000115147.2}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000115147.2};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; D3YWU5; -.
DR   ProteomicsDB; 353447; -.
DR   Ensembl; ENSMUST00000125933.2; ENSMUSP00000115147.2; ENSMUSG00000000215.12.
DR   AGR; MGI:96573; -.
DR   MGI; MGI:96573; Ins2.
DR   VEuPathDB; HostDB:ENSMUSG00000000215; -.
DR   GeneTree; ENSGT00390000015440; -.
DR   ChiTaRS; Ins2; mouse.
DR   Proteomes; UP000000589; Chromosome 7.
DR   Bgee; ENSMUSG00000000215; Expressed in islet of Langerhans and 59 other cell types or tissues.
DR   ExpressionAtlas; D3YWU5; baseline and differential.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0005179; F:hormone activity; IEA:InterPro.
DR   CDD; cd04367; IlGF_insulin_like; 1.
DR   Gene3D; 1.10.100.10; Insulin-like; 1.
DR   InterPro; IPR004825; Insulin.
DR   InterPro; IPR016179; Insulin-like.
DR   InterPro; IPR036438; Insulin-like_sf.
DR   PANTHER; PTHR11454:SF33; INSULIN-2; 1.
DR   PANTHER; PTHR11454; INSULIN/INSULIN GROWTH FACTOR; 1.
DR   Pfam; PF00049; Insulin; 1.
DR   PRINTS; PR00277; INSULIN.
DR   SMART; SM00078; IlGF; 1.
DR   SUPFAM; SSF56994; Insulin-like; 1.
PE   1: Evidence at protein level;
KW   Proteomics identification {ECO:0007829|ProteomicsDB:D3YWU5};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           25..70
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5008413269"
FT   DOMAIN          28..70
FT                   /note="Insulin-like"
FT                   /evidence="ECO:0000259|SMART:SM00078"
FT   NON_TER         70
FT                   /evidence="ECO:0000313|Ensembl:ENSMUSP00000115147.2"
SQ   SEQUENCE   70 AA;  8151 MW;  328F1449986DB475 CRC64;
     MALWMRFLPL LALLFLWESH PTQAFVKQHL CGSHLVEALY LVCGERGFFY TPMSRREVED
     PQAGELLQLD
//