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D3YWI8

- D3YWI8_MOUSE

UniProt

D3YWI8 - D3YWI8_MOUSE

Protein
Submitted name:

Intraflagellar transport protein 80 homolog

Gene

Ift80

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Protein predictedi
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    • History
      Entry version 29 (01 Oct 2014)
      Sequence version 1 (20 Apr 2010)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. bone morphogenesis Source: MGI
    2. chondrocyte differentiation Source: MGI
    3. cilium assembly Source: MGI
    4. cilium morphogenesis Source: MGI
    5. intraciliary transport Source: MGI
    6. negative regulation of epithelial cell proliferation Source: MGI
    7. negative regulation of non-canonical Wnt signaling pathway Source: MGI
    8. osteoblast differentiation Source: MGI
    9. positive regulation of smoothened signaling pathway Source: MGI
    10. smoothened signaling pathway Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Intraflagellar transport protein 80 homologImported
    Gene namesi
    Name:Ift80Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 3

    Organism-specific databases

    MGIiMGI:1915509. Ift80.

    Subcellular locationi

    GO - Cellular componenti

    1. centrosome Source: MGI
    2. ciliary basal body Source: MGI
    3. cilium Source: MGI
    4. intraciliary transport particle B Source: MGI

    Expressioni

    Gene expression databases

    ArrayExpressiD3YWI8.
    BgeeiD3YWI8.

    Structurei

    3D structure databases

    ProteinModelPortaliD3YWI8.
    SMRiD3YWI8. Positions 9-209.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    RepeatUniRule annotation, WD repeatUniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00440000033499.
    HOGENOMiHOG000207221.

    Family and domain databases

    Gene3Di2.130.10.10. 1 hit.
    InterProiIPR015943. WD40/YVTN_repeat-like_dom.
    IPR001680. WD40_repeat.
    IPR017986. WD40_repeat_dom.
    [Graphical view]
    PfamiPF00400. WD40. 1 hit.
    [Graphical view]
    SMARTiSM00320. WD40. 4 hits.
    [Graphical view]
    SUPFAMiSSF50978. SSF50978. 1 hit.
    PROSITEiPS50082. WD_REPEATS_2. 1 hit.
    PS50294. WD_REPEATS_REGION. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    D3YWI8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRLKISLSKE PKHQELVSCV GWTTAEELYS CSDDHQIVKW NLLTSETSLI    50
    VKLPDDIYPI DLHWFPKSLG IKKQTQAESF VLTSSDGKFH LISKLGRVEK 100
    SVEAHCGAVL AGRWNYEGTA LVTVGEDGQV KIWSKTGMLR STLAQQGTPV 150
    YSVAWGPDSE KVLYTAGKQL IIKPLQPNAK VLQWKAHDGI ILKVDWNSVN 200
    DLILSAGED 209
    Length:209
    Mass (Da):23,228
    Last modified:April 20, 2010 - v1
    Checksum:iEB8A07D9D4212918
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei209 – 2091Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC115062 Genomic DNA. No translation available.
    AC122876 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000154741; ENSMUSP00000118406; ENSMUSG00000027778.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC115062 Genomic DNA. No translation available.
    AC122876 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali D3YWI8.
    SMRi D3YWI8. Positions 9-209.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000154741 ; ENSMUSP00000118406 ; ENSMUSG00000027778 .

    Organism-specific databases

    MGIi MGI:1915509. Ift80.

    Phylogenomic databases

    GeneTreei ENSGT00440000033499.
    HOGENOMi HOG000207221.

    Miscellaneous databases

    NextBioi 35549112.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi D3YWI8.
    Bgeei D3YWI8.

    Family and domain databases

    Gene3Di 2.130.10.10. 1 hit.
    InterProi IPR015943. WD40/YVTN_repeat-like_dom.
    IPR001680. WD40_repeat.
    IPR017986. WD40_repeat_dom.
    [Graphical view ]
    Pfami PF00400. WD40. 1 hit.
    [Graphical view ]
    SMARTi SM00320. WD40. 4 hits.
    [Graphical view ]
    SUPFAMi SSF50978. SSF50978. 1 hit.
    PROSITEi PS50082. WD_REPEATS_2. 1 hit.
    PS50294. WD_REPEATS_REGION. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiD3YWI8_MOUSE
    AccessioniPrimary (citable) accession number: D3YWI8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 20, 2010
    Last sequence update: April 20, 2010
    Last modified: October 1, 2014
    This is version 29 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3