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Protein
Submitted name:

Rho guanine nucleotide exchange factor 18

Gene

Arhgef18

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. guanyl-nucleotide exchange factor activity Source: MGI

GO - Biological processi

  1. actin cytoskeleton organization Source: MGI
  2. positive regulation of GTPase activity Source: GOC
  3. regulation of cell shape Source: MGI
  4. small GTPase mediated signal transduction Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Rho guanine nucleotide exchange factor 18Imported
Gene namesi
Name:Arhgef18Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:2142567. Arhgef18.

Subcellular locationi

GO - Cellular componenti

  1. apical part of cell Source: MGI
  2. cytoplasm Source: MGI
  3. extracellular vesicular exosome Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiD3YWI3.
ExpressionAtlasiD3YWI3. baseline and differential.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000119193.

Family and domain databases

InterProiIPR015721. RhoGEF-like.
[Graphical view]
PANTHERiPTHR22825. PTHR22825. 1 hit.

Sequencei

Sequence statusi: Fragment.

D3YWI3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTISQKGGLQ PTPSPAGSGV RLGPIAGDMD EADSVFLKLK QTADDSLSLT
60 70 80 90 100
SSNAESVFIE DPYIASLRCE IESDAHEFEA ESWSLSVDLA YAKKQKKEVV

KRQDVLY
Length:107
Mass (Da):11,638
Last modified:April 20, 2010 - v1
Checksum:iFD90745784795A20
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei107 – 1071Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC169677 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000145394; ENSMUSP00000118410; ENSMUSG00000004568.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC169677 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000145394; ENSMUSP00000118410; ENSMUSG00000004568.

Organism-specific databases

MGIiMGI:2142567. Arhgef18.

Phylogenomic databases

GeneTreeiENSGT00760000119193.

Miscellaneous databases

ChiTaRSiArhgef18. mouse.
NextBioi35549109.
SOURCEiSearch...

Gene expression databases

BgeeiD3YWI3.
ExpressionAtlasiD3YWI3. baseline and differential.

Family and domain databases

InterProiIPR015721. RhoGEF-like.
[Graphical view]
PANTHERiPTHR22825. PTHR22825. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiD3YWI3_MOUSE
AccessioniPrimary (citable) accession number: D3YWI3
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: February 4, 2015
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.