D3YWG3 (D3YWG3_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Ribonuclease RuleBase RU003515
EC=3.1.26.- RuleBase RU003515

Gene names

Name:

Rnaseh2a Ensembl ENSMUSP00000118442 MGI 1916974

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000118442

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	54 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Endonuclease that specifically degrades the RNA of RNA-DNA hybrids By similarity. RuleBase RU003515
Catalytic activity	Endonucleolytic cleavage to 5'-phosphomonoester. RuleBase RU003515
Sequence similarities	Belongs to the RNase HII family. RuleBase RU003515
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000118442

Ontologies

Keywords
Molecular function	Endonuclease RuleBase RU003515 Hydrolase Nuclease
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	RNA catabolic process Inferred from electronic annotation. Source: Compara nucleic acid phosphodiester bond hydrolysis Inferred from electronic annotation. Source: GOC
Cellular_component	ribonuclease H2 complex Inferred from direct assay PubMed 19923215. Source: MGI
Molecular_function	RNA binding Inferred from electronic annotation. Source: InterPro ribonuclease H activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	54	1	Ensembl ENSMUSP00000118442

Sequences

	Sequence		Length	Mass (Da)
	D3YWG3 [UniParc]. Last modified April 20, 2010. Version 1. Checksum: E3EF570F77767B76	FASTA	54	5,795
	10 20 30 40 50 MDLSELERDN TGRCRLSSPV PAVCLKEPCV LGVDEAGRGP VLGPMVYAIC YCPL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000118442.
[2]	Ensembl Submitted (MAY-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000118442.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC163703 Genomic DNA. No translation available.
IPI	IPI00831388.
3D structure databases
ProteinModelPortal	D3YWG3.
SMR	D3YWG3. Positions 1-54.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000140561; ENSMUSP00000118442; ENSMUSG00000052926.
Organism-specific databases
MGI	MGI:1916974. Rnaseh2a.
Phylogenomic databases
GeneTree	ENSGT00390000010768.
Gene expression databases
ArrayExpress	D3YWG3.
Bgee	D3YWG3.
Family and domain databases
InterPro	IPR001352. RNase_HII/HIII. IPR024567. RNase_HII/HIII_dom. IPR012337. RNaseH-like_dom. [Graphical view]
PANTHER	PTHR10954. PTHR10954. 1 hit.
Pfam	PF01351. RNase_HII. 1 hit. [Graphical view]
SUPFAM	SSF53098. RNaseH_fold. 1 hit.
ProtoNet	Search...
Other
ChiTaRS	RNASEH2A. mouse.
NextBio	35549089.
SOURCE	Search...

Entry information

Entry name

D3YWG3_MOUSE

Accession

Primary (citable) accession number: D3YWG3

Entry history

Integrated into UniProtKB/TrEMBL:	April 20, 2010
Last sequence update:	April 20, 2010
Last modified:	April 3, 2013
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)