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D3YWD6

- D3YWD6_MOUSE

UniProt

D3YWD6 - D3YWD6_MOUSE

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Protein
Submitted name:

NAD-dependent protein deacetylase sirtuin-3

Gene
Sirt3
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. NAD+ binding Source: InterPro
  2. NAD-dependent histone deacetylase activity (H3-K14 specific) Source: MGI
  3. zinc ion binding Source: Ensembl

GO - Biological processi

  1. aerobic respiration Source: Ensembl
  2. histone H3 deacetylation Source: GOC
  3. peptidyl-lysine deacetylation Source: Ensembl
  4. protein deacetylation Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
NAD-dependent protein deacetylase sirtuin-3Imported
Gene namesi
Name:Sirt3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 7

Organism-specific databases

MGIiMGI:1927665. Sirt3.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: MGI
  2. membrane Source: MGI
  3. mitochondrion Source: MGI
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiD3YWD6.

Expressioni

Gene expression databases

ArrayExpressiD3YWD6.
BgeeiD3YWD6.

Structurei

3D structure databases

ProteinModelPortaliD3YWD6.
SMRiD3YWD6. Positions 1-100.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00740000115546.

Family and domain databases

Gene3Di3.40.50.1220. 1 hit.
InterProiIPR029035. DHS-like_NAD/FAD-binding_dom.
IPR003000. Sirtuin.
IPR026590. Ssirtuin_cat_dom.
[Graphical view]
PANTHERiPTHR11085. PTHR11085. 1 hit.
PfamiPF02146. SIR2. 1 hit.
[Graphical view]
SUPFAMiSSF52467. SSF52467. 1 hit.
PROSITEiPS50305. SIRTUIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

D3YWD6-1 [UniParc]FASTAAdd to Basket

« Hide

MVGAGISTPS GIPDFRSPGS GLYSNLQQYD IPYPEAIFEL GFFFHNPKPF    50
FMLAKELYPG HYRPNVTHYF LRLLHDKELL LRLYTQNIDG LERASGIPAS 100
Length:100
Mass (Da):11,362
Last modified:April 20, 2010 - v1
Checksum:iBE39180ACA0413EF
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei100 – 1001Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC107815 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000137710; ENSMUSP00000115202; ENSMUSG00000025486.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC107815 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali D3YWD6.
SMRi D3YWD6. Positions 1-100.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi D3YWD6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000137710 ; ENSMUSP00000115202 ; ENSMUSG00000025486 .

Organism-specific databases

MGIi MGI:1927665. Sirt3.

Phylogenomic databases

GeneTreei ENSGT00740000115546.

Miscellaneous databases

ChiTaRSi SIRT3. mouse.
NextBioi 35549076.
SOURCEi Search...

Gene expression databases

ArrayExpressi D3YWD6.
Bgeei D3YWD6.

Family and domain databases

Gene3Di 3.40.50.1220. 1 hit.
InterProi IPR029035. DHS-like_NAD/FAD-binding_dom.
IPR003000. Sirtuin.
IPR026590. Ssirtuin_cat_dom.
[Graphical view ]
PANTHERi PTHR11085. PTHR11085. 1 hit.
Pfami PF02146. SIR2. 1 hit.
[Graphical view ]
SUPFAMi SSF52467. SSF52467. 1 hit.
PROSITEi PS50305. SIRTUIN. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiD3YWD6_MOUSE
AccessioniPrimary (citable) accession number: D3YWD6
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: July 9, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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