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Protein
Submitted name:

Exostosin-1

Gene

Ext1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. acetylglucosaminyltransferase activity Source: MGI
  2. glucuronosyltransferase activity Source: MGI
  3. protein heterodimerization activity Source: MGI
  4. protein homodimerization activity Source: MGI
  5. transferase activity, transferring glycosyl groups Source: MGI

GO - Biological processi

  1. axon guidance Source: MGI
  2. brain development Source: MGI
  3. cellular polysaccharide biosynthetic process Source: MGI
  4. embryonic skeletal joint development Source: MGI
  5. endoderm development Source: MGI
  6. gastrulation Source: MGI
  7. glycosaminoglycan biosynthetic process Source: MGI
  8. heparan sulfate proteoglycan biosynthetic process Source: MGI
  9. heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process Source: MGI
  10. mesoderm development Source: MGI
  11. olfactory bulb development Source: MGI
  12. ossification Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Exostosin-1Imported
Gene namesi
Name:Ext1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 15

Organism-specific databases

MGIiMGI:894663. Ext1.

Subcellular locationi

GO - Cellular componenti

  1. endoplasmic reticulum Source: MGI
  2. Golgi apparatus Source: MGI
  3. integral component of membrane Source: InterPro
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiD3YVY6.

Expressioni

Gene expression databases

BgeeiD3YVY6.
ExpressionAtlasiD3YVY6. baseline and differential.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00550000074496.
HOGENOMiHOG000068095.

Family and domain databases

Gene3Di3.90.550.10. 1 hit.
InterProiIPR004263. Exostosin.
IPR027670. Exostosin-1.
IPR015338. EXT_C.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PANTHERiPTHR11062:SF45. PTHR11062:SF45. 1 hit.
PfamiPF03016. Exostosin. 1 hit.
PF09258. Glyco_transf_64. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

D3YVY6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLSISRYDY REMLHNATFC LVPRGRRLGS FRFLEALQAA CVPVMLSNGW
60 70 80 90 100
ELPFSEVINW NQAAVIGDER LLLQIPSTIR SIHQDKILAL RQQTQFLWEA
110 120 130 140 150
YFSSVEKIVL TTLEIIQDRI FKHISRNSLI WNKHPGGLFV LPQYSSYLGD
160 170 180 190 200
FPYYYANLGL KPPSKFTAVI HAVTPLVSQS QPVLKLLVAA AKSQYCAQII
210 220 230
VLWNCDKPLP AKHRWPATAV PVIVIEGESK VMSSRFLPY
Length:239
Mass (Da):27,204
Last modified:April 19, 2010 - v1
Checksum:i5BFE7E597D3CBE2A
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei239 – 2391Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC122185 Genomic DNA. No translation available.
AC122378 Genomic DNA. No translation available.
AC123931 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000110244; ENSMUSP00000105873; ENSMUSG00000061731.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC122185 Genomic DNA. No translation available.
AC122378 Genomic DNA. No translation available.
AC123931 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiD3YVY6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000110244; ENSMUSP00000105873; ENSMUSG00000061731.

Organism-specific databases

MGIiMGI:894663. Ext1.

Phylogenomic databases

GeneTreeiENSGT00550000074496.
HOGENOMiHOG000068095.

Miscellaneous databases

ChiTaRSiExt1. mouse.
NextBioi35548979.
SOURCEiSearch...

Gene expression databases

BgeeiD3YVY6.
ExpressionAtlasiD3YVY6. baseline and differential.

Family and domain databases

Gene3Di3.90.550.10. 1 hit.
InterProiIPR004263. Exostosin.
IPR027670. Exostosin-1.
IPR015338. EXT_C.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PANTHERiPTHR11062:SF45. PTHR11062:SF45. 1 hit.
PfamiPF03016. Exostosin. 1 hit.
PF09258. Glyco_transf_64. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (APR-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiD3YVY6_MOUSE
AccessioniPrimary (citable) accession number: D3YVY6
Entry historyi
Integrated into UniProtKB/TrEMBL: April 19, 2010
Last sequence update: April 19, 2010
Last modified: March 31, 2015
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.