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D3YVX9

- D3YVX9_MOUSE

UniProt

D3YVX9 - D3YVX9_MOUSE

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Protein
Submitted name: Mitogen-activated protein kinase kinase kinase 1
Gene
Map3k1
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. JUN kinase kinase activity Source: MGI
  2. MAP kinase kinase kinase activity Source: RefGenome
  3. protein binding Source: MGI
  4. protein kinase activity Source: MGI
  5. zinc ion binding Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. JNK cascade Source: MGI
  2. activation of JUN kinase activity Source: MGI
  3. activation of MAPKK activity Source: GOC
  4. apoptotic mitochondrial changes Source: MGI
  5. camera-type eye development Source: MGI
  6. cellular response to mechanical stimulus Source: Ensembl
  7. epithelial cell morphogenesis Source: MGI
  8. eyelid development in camera-type eye Source: MGI
  9. positive regulation of actin filament polymerization Source: MGI
  10. protein phosphorylation Source: GOC
  11. regulation of cell migration Source: MGI
  12. transforming growth factor beta receptor signaling pathway Source: MGI
  13. wound healing Source: MGI
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_188530. FCERI mediated MAPK activation.
REACT_202898. TRAF6 mediated NF-kB activation.

Names & Taxonomyi

Protein namesi
Submitted name:
Mitogen-activated protein kinase kinase kinase 1Imported
Gene namesi
Name:Map3k1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 13

Organism-specific databases

MGIiMGI:1346872. Map3k1.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: RefGenome
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiD3YVX9.

Expressioni

Gene expression databases

ArrayExpressiD3YVX9.
BgeeiD3YVX9.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00750000117575.

Family and domain databases

InterProiIPR007527. Znf_SWIM.
[Graphical view]
PfamiPF04434. SWIM. 1 hit.
[Graphical view]
PROSITEiPS50966. ZF_SWIM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

D3YVX9-1 [UniParc]FASTAAdd to Basket

« Hide

MENKETLKGL HKMEDRPEER MIREKLKATC MPAWKHEWLE RRNRRGPVVV    50
KPIPIKGDGS EMNNLAAEPQ GEGQAGSAAP APKGRRSPSP GSSPSGRSVK 100
PESPGVRRKR VSPVPFQSGR ITPPRRAPSP DGFSPYSPEE TSRRVNKVMR 150
ARLYLLQQIG PNSFLIGGDS PDNKYRVFIG PQNCSCGRGA FCIHLLFVML 200
RVFQLEPSDP MLWRKTLKNF EVESLFQKYH SRRSSRIKAP SRNTIQKFVS 250
RMSNCHTLSS SST 263
Length:263
Mass (Da):29,637
Last modified:May 14, 2014 - v2
Checksum:iEB698A02CEB177A6
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei263 – 2631Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC118704 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000145055; ENSMUSP00000117863; ENSMUSG00000021754.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC118704 Genomic DNA. No translation available.

3D structure databases

ModBasei Search...

Proteomic databases

PRIDEi D3YVX9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000145055 ; ENSMUSP00000117863 ; ENSMUSG00000021754 .

Organism-specific databases

MGIi MGI:1346872. Map3k1.

Phylogenomic databases

GeneTreei ENSGT00750000117575.

Enzyme and pathway databases

Reactomei REACT_188530. FCERI mediated MAPK activation.
REACT_202898. TRAF6 mediated NF-kB activation.

Miscellaneous databases

ChiTaRSi MAP3K1. mouse.
NextBioi 35548973.
SOURCEi Search...

Gene expression databases

ArrayExpressi D3YVX9.
Bgeei D3YVX9.

Family and domain databases

InterProi IPR007527. Znf_SWIM.
[Graphical view ]
Pfami PF04434. SWIM. 1 hit.
[Graphical view ]
PROSITEi PS50966. ZF_SWIM. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiD3YVX9_MOUSE
AccessioniPrimary (citable) accession number: D3YVX9
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: May 14, 2014
Last modified: September 3, 2014
This is version 33 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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