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D3YVX9

- D3YVX9_MOUSE

UniProt

D3YVX9 - D3YVX9_MOUSE

Protein
Submitted name:

Mitogen-activated protein kinase kinase kinase 1

Gene

Map3k1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Protein predictedi
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    • History
      Entry version 34 (01 Oct 2014)
      Sequence version 2 (14 May 2014)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. JUN kinase kinase activity Source: MGI
    2. protein binding Source: MGI
    3. protein kinase activity Source: MGI
    4. zinc ion binding Source: InterPro

    GO - Biological processi

    1. activation of JUN kinase activity Source: MGI
    2. apoptotic mitochondrial changes Source: MGI
    3. camera-type eye development Source: MGI
    4. cellular response to mechanical stimulus Source: Ensembl
    5. epithelial cell morphogenesis Source: MGI
    6. eyelid development in camera-type eye Source: MGI
    7. JNK cascade Source: MGI
    8. positive regulation of actin filament polymerization Source: MGI
    9. protein phosphorylation Source: GOC
    10. regulation of cell migration Source: MGI
    11. transforming growth factor beta receptor signaling pathway Source: MGI
    12. wound healing Source: MGI

    Enzyme and pathway databases

    ReactomeiREACT_188530. FCERI mediated MAPK activation.
    REACT_202898. TRAF6 mediated NF-kB activation.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Mitogen-activated protein kinase kinase kinase 1Imported
    Gene namesi
    Name:Map3k1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 13

    Organism-specific databases

    MGIiMGI:1346872. Map3k1.

    PTM / Processingi

    Proteomic databases

    PRIDEiD3YVX9.

    Expressioni

    Gene expression databases

    ArrayExpressiD3YVX9.
    BgeeiD3YVX9.

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00750000117575.

    Family and domain databases

    InterProiIPR007527. Znf_SWIM.
    [Graphical view]
    PfamiPF04434. SWIM. 1 hit.
    [Graphical view]
    PROSITEiPS50966. ZF_SWIM. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    D3YVX9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MENKETLKGL HKMEDRPEER MIREKLKATC MPAWKHEWLE RRNRRGPVVV    50
    KPIPIKGDGS EMNNLAAEPQ GEGQAGSAAP APKGRRSPSP GSSPSGRSVK 100
    PESPGVRRKR VSPVPFQSGR ITPPRRAPSP DGFSPYSPEE TSRRVNKVMR 150
    ARLYLLQQIG PNSFLIGGDS PDNKYRVFIG PQNCSCGRGA FCIHLLFVML 200
    RVFQLEPSDP MLWRKTLKNF EVESLFQKYH SRRSSRIKAP SRNTIQKFVS 250
    RMSNCHTLSS SST 263
    Length:263
    Mass (Da):29,637
    Last modified:May 14, 2014 - v2
    Checksum:iEB698A02CEB177A6
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei263 – 2631Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC118704 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000145055; ENSMUSP00000117863; ENSMUSG00000021754.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC118704 Genomic DNA. No translation available.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi D3YVX9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000145055 ; ENSMUSP00000117863 ; ENSMUSG00000021754 .

    Organism-specific databases

    MGIi MGI:1346872. Map3k1.

    Phylogenomic databases

    GeneTreei ENSGT00750000117575.

    Enzyme and pathway databases

    Reactomei REACT_188530. FCERI mediated MAPK activation.
    REACT_202898. TRAF6 mediated NF-kB activation.

    Miscellaneous databases

    ChiTaRSi MAP3K1. mouse.
    NextBioi 35548973.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi D3YVX9.
    Bgeei D3YVX9.

    Family and domain databases

    InterProi IPR007527. Znf_SWIM.
    [Graphical view ]
    Pfami PF04434. SWIM. 1 hit.
    [Graphical view ]
    PROSITEi PS50966. ZF_SWIM. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiD3YVX9_MOUSE
    AccessioniPrimary (citable) accession number: D3YVX9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 20, 2010
    Last sequence update: May 14, 2014
    Last modified: October 1, 2014
    This is version 34 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3