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Protein
Submitted name:

Mitogen-activated protein kinase kinase kinase 1

Gene

Map3k1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-MMU-166058 MyD88:Mal cascade initiated on plasma membrane
R-MMU-2871796 FCERI mediated MAPK activation
R-MMU-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
R-MMU-975871 MyD88 cascade initiated on plasma membrane

Names & Taxonomyi

Protein namesi
Submitted name:
Mitogen-activated protein kinase kinase kinase 1Imported
Gene namesi
Name:Map3k1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 13

Organism-specific databases

MGIiMGI:1346872 Map3k1

PTM / Processingi

Proteomic databases

PeptideAtlasiD3YVX9
PRIDEiD3YVX9

Expressioni

Gene expression databases

BgeeiENSMUSG00000021754
ExpressionAtlasiD3YVX9 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini175 – 203SWIM-typeInterPro annotationAdd BLAST29

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG4279 Eukaryota
ENOG410XQGS LUCA
GeneTreeiENSGT00800000124036

Family and domain databases

InterProiView protein in InterPro
IPR007527 Znf_SWIM
PfamiView protein in Pfam
PF04434 SWIM, 1 hit
PROSITEiView protein in PROSITE
PS50966 ZF_SWIM, 1 hit

Sequencei

Sequence statusi: Fragment.

D3YVX9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENKETLKGL HKMEDRPEER MIREKLKATC MPAWKHEWLE RRNRRGPVVV
60 70 80 90 100
KPIPIKGDGS EMNNLAAEPQ GEGQAGSAAP APKGRRSPSP GSSPSGRSVK
110 120 130 140 150
PESPGVRRKR VSPVPFQSGR ITPPRRAPSP DGFSPYSPEE TSRRVNKVMR
160 170 180 190 200
ARLYLLQQIG PNSFLIGGDS PDNKYRVFIG PQNCSCGRGA FCIHLLFVML
210 220 230 240 250
RVFQLEPSDP MLWRKTLKNF EVESLFQKYH SRRSSRIKAP SRNTIQKFVS
260
RMSNCHTLSS SST
Length:263
Mass (Da):29,637
Last modified:October 5, 2016 - v8
Checksum:iEB698A02CEB177A6
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei263Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC118704 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSMUST00000145055; ENSMUSP00000117863; ENSMUSG00000021754

Similar proteinsi

Entry informationi

Entry nameiD3YVX9_MOUSE
AccessioniPrimary (citable) accession number: D3YVX9
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: October 5, 2016
Last modified: April 25, 2018
This is version 58 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health