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Protein
Submitted name:

Galectin-3

Gene

Lgals3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. chemoattractant activity Source: MGI
  2. IgE binding Source: MGI
  3. laminin binding Source: MGI
  4. poly(A) RNA binding Source: MGI

GO - Biological processi

  1. eosinophil chemotaxis Source: MGI
  2. epithelial cell differentiation Source: Ensembl
  3. extracellular matrix organization Source: MGI
  4. macrophage chemotaxis Source: MGI
  5. monocyte chemotaxis Source: MGI
  6. mononuclear cell migration Source: MGI
  7. negative regulation of endocytosis Source: MGI
  8. negative regulation of extrinsic apoptotic signaling pathway Source: MGI
  9. neutrophil chemotaxis Source: MGI
  10. positive chemotaxis Source: MGI
  11. positive regulation of calcium ion import Source: MGI
  12. positive regulation of mononuclear cell migration Source: MGI
  13. regulation of extrinsic apoptotic signaling pathway via death domain receptors Source: MGI
  14. regulation of T cell apoptotic process Source: MGI
  15. regulation of T cell proliferation Source: MGI
  16. skeletal system development Source: MGI
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_342554. Advanced glycosylation endproduct receptor signaling.

Names & Taxonomyi

Protein namesi
Submitted name:
Galectin-3Imported
Gene namesi
Name:Lgals3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:96778. Lgals3.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: MGI
  2. external side of plasma membrane Source: MGI
  3. extracellular space Source: MGI
  4. extracellular vesicular exosome Source: MGI
  5. immunological synapse Source: MGI
  6. membrane Source: MGI
  7. mitochondrial inner membrane Source: MGI
  8. nucleus Source: MGI
  9. proteinaceous extracellular matrix Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiD3YVT4.
ExpressionAtlasiD3YVT4. baseline and differential.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000119105.

Sequencei

Sequence statusi: Fragment.

D3YVT4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADSFSLNDA LAGSGNPNPQ GYPGAWGNQP GAGGYPGAAY PGAYPGQAPP
60 70 80 90
GAYPGQAPPG AYPGQAPPSA YPGPTAPGAY PGPTAPGAYP GSTA
Length:94
Mass (Da):8,872
Last modified:April 19, 2010 - v1
Checksum:i733E6BB7E383255A
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei94 – 941Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC123665 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000144794; ENSMUSP00000114177; ENSMUSG00000050335.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC123665 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000144794; ENSMUSP00000114177; ENSMUSG00000050335.

Organism-specific databases

MGIiMGI:96778. Lgals3.

Phylogenomic databases

GeneTreeiENSGT00760000119105.

Enzyme and pathway databases

ReactomeiREACT_342554. Advanced glycosylation endproduct receptor signaling.

Miscellaneous databases

ChiTaRSiLgals3. mouse.
NextBioi35548938.
SOURCEiSearch...

Gene expression databases

BgeeiD3YVT4.
ExpressionAtlasiD3YVT4. baseline and differential.

Family and domain databases

ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (APR-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiD3YVT4_MOUSE
AccessioniPrimary (citable) accession number: D3YVT4
Entry historyi
Integrated into UniProtKB/TrEMBL: April 19, 2010
Last sequence update: April 19, 2010
Last modified: March 31, 2015
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.