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D3YVQ5

- D3YVQ5_MOUSE

UniProt

D3YVQ5 - D3YVQ5_MOUSE

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Protein
Submitted name:

NAD-dependent protein deacetylase sirtuin-3

Gene

Sirt3

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. NAD+ binding Source: InterPro
  2. NAD-dependent histone deacetylase activity (H3-K14 specific) Source: MGI

GO - Biological processi

  1. histone H3 deacetylation Source: GOC
  2. protein deacetylation Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
NAD-dependent protein deacetylase sirtuin-3Imported
Gene namesi
Name:Sirt3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 7

Organism-specific databases

MGIiMGI:1927665. Sirt3.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: MGI
  2. membrane Source: MGI
  3. mitochondrion Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiD3YVQ5.
ExpressionAtlasiD3YVQ5. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliD3YVQ5.
SMRiD3YVQ5. Positions 1-182.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00740000115546.
HOGENOMiHOG000085952.

Family and domain databases

Gene3Di3.40.50.1220. 1 hit.
InterProiIPR029035. DHS-like_NAD/FAD-binding_dom.
IPR003000. Sirtuin.
IPR026590. Ssirtuin_cat_dom.
[Graphical view]
PANTHERiPTHR11085. PTHR11085. 1 hit.
PfamiPF02146. SIR2. 1 hit.
[Graphical view]
SUPFAMiSSF52467. SSF52467. 1 hit.
PROSITEiPS50305. SIRTUIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

D3YVQ5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVGAGISTPS GIPDFRSPGS GLYSNLQQYD IPYPEAIFEL GFFFHNPKPF
60 70 80 90 100
FMLAKELYPG HYRPNVTHYF LRLLHDKELL LRLYTQNIDG LERASGIPAS
110 120 130 140 150
KLVEAHGTFV TATCTVCRRS FPGEDIWVEP FASLSEAVQK SVPRLLINRD
160 170 180
LVGPFVLSPR RKDVVQLGDV VHGVERLVDL LG
Length:182
Mass (Da):20,384
Last modified:April 20, 2010 - v1
Checksum:i9E513E9211121F43
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei182 – 1821Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC107815 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000137024; ENSMUSP00000114247; ENSMUSG00000025486.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC107815 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali D3YVQ5.
SMRi D3YVQ5. Positions 1-182.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000137024 ; ENSMUSP00000114247 ; ENSMUSG00000025486 .

Organism-specific databases

MGIi MGI:1927665. Sirt3.

Phylogenomic databases

GeneTreei ENSGT00740000115546.
HOGENOMi HOG000085952.

Miscellaneous databases

ChiTaRSi SIRT3. mouse.
NextBioi 35548917.
SOURCEi Search...

Gene expression databases

Bgeei D3YVQ5.
ExpressionAtlasi D3YVQ5. baseline and differential.

Family and domain databases

Gene3Di 3.40.50.1220. 1 hit.
InterProi IPR029035. DHS-like_NAD/FAD-binding_dom.
IPR003000. Sirtuin.
IPR026590. Ssirtuin_cat_dom.
[Graphical view ]
PANTHERi PTHR11085. PTHR11085. 1 hit.
Pfami PF02146. SIR2. 1 hit.
[Graphical view ]
SUPFAMi SSF52467. SSF52467. 1 hit.
PROSITEi PS50305. SIRTUIN. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiD3YVQ5_MOUSE
AccessioniPrimary (citable) accession number: D3YVQ5
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: October 29, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3