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D3YVQ5

- D3YVQ5_MOUSE

UniProt

D3YVQ5 - D3YVQ5_MOUSE

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Protein
Submitted name: NAD-dependent protein deacetylase sirtuin-3
Gene
Sirt3
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. NAD+ binding Source: InterPro
  2. NAD-dependent histone deacetylase activity (H3-K14 specific) Source: MGI

GO - Biological processi

  1. histone H3 deacetylation Source: GOC
  2. protein deacetylation Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
NAD-dependent protein deacetylase sirtuin-3Imported
Gene namesi
Name:Sirt3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 7

Organism-specific databases

MGIiMGI:1927665. Sirt3.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: MGI
  2. membrane Source: MGI
  3. mitochondrion Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiD3YVQ5.
BgeeiD3YVQ5.

Structurei

3D structure databases

ProteinModelPortaliD3YVQ5.
SMRiD3YVQ5. Positions 1-182.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00740000115546.
HOGENOMiHOG000085952.

Family and domain databases

Gene3Di3.40.50.1220. 1 hit.
InterProiIPR029035. DHS-like_NAD/FAD-binding_dom.
IPR003000. Sirtuin.
IPR026590. Ssirtuin_cat_dom.
[Graphical view]
PANTHERiPTHR11085. PTHR11085. 1 hit.
PfamiPF02146. SIR2. 1 hit.
[Graphical view]
SUPFAMiSSF52467. SSF52467. 1 hit.
PROSITEiPS50305. SIRTUIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

D3YVQ5-1 [UniParc]FASTAAdd to Basket

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MVGAGISTPS GIPDFRSPGS GLYSNLQQYD IPYPEAIFEL GFFFHNPKPF    50
FMLAKELYPG HYRPNVTHYF LRLLHDKELL LRLYTQNIDG LERASGIPAS 100
KLVEAHGTFV TATCTVCRRS FPGEDIWVEP FASLSEAVQK SVPRLLINRD 150
LVGPFVLSPR RKDVVQLGDV VHGVERLVDL LG 182
Length:182
Mass (Da):20,384
Last modified:April 20, 2010 - v1
Checksum:i9E513E9211121F43
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei182 – 1821Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC107815 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000137024; ENSMUSP00000114247; ENSMUSG00000025486.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC107815 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali D3YVQ5.
SMRi D3YVQ5. Positions 1-182.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000137024 ; ENSMUSP00000114247 ; ENSMUSG00000025486 .

Organism-specific databases

MGIi MGI:1927665. Sirt3.

Phylogenomic databases

GeneTreei ENSGT00740000115546.
HOGENOMi HOG000085952.

Miscellaneous databases

ChiTaRSi SIRT3. mouse.
NextBioi 35548917.
SOURCEi Search...

Gene expression databases

ArrayExpressi D3YVQ5.
Bgeei D3YVQ5.

Family and domain databases

Gene3Di 3.40.50.1220. 1 hit.
InterProi IPR029035. DHS-like_NAD/FAD-binding_dom.
IPR003000. Sirtuin.
IPR026590. Ssirtuin_cat_dom.
[Graphical view ]
PANTHERi PTHR11085. PTHR11085. 1 hit.
Pfami PF02146. SIR2. 1 hit.
[Graphical view ]
SUPFAMi SSF52467. SSF52467. 1 hit.
PROSITEi PS50305. SIRTUIN. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiD3YVQ5_MOUSE
AccessioniPrimary (citable) accession number: D3YVQ5
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: July 9, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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