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D3YVQ5

- D3YVQ5_MOUSE

UniProt

D3YVQ5 - D3YVQ5_MOUSE

Protein
Submitted name:

NAD-dependent protein deacetylase sirtuin-3

Gene

Sirt3

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 34 (01 Oct 2014)
      Sequence version 1 (20 Apr 2010)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. NAD+ binding Source: InterPro
    2. NAD-dependent histone deacetylase activity (H3-K14 specific) Source: MGI

    GO - Biological processi

    1. histone H3 deacetylation Source: GOC
    2. protein deacetylation Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    NAD-dependent protein deacetylase sirtuin-3Imported
    Gene namesi
    Name:Sirt3Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 7

    Organism-specific databases

    MGIiMGI:1927665. Sirt3.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: MGI
    2. membrane Source: MGI
    3. mitochondrion Source: MGI

    Expressioni

    Gene expression databases

    ArrayExpressiD3YVQ5.
    BgeeiD3YVQ5.

    Structurei

    3D structure databases

    ProteinModelPortaliD3YVQ5.
    SMRiD3YVQ5. Positions 1-182.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00740000115546.
    HOGENOMiHOG000085952.

    Family and domain databases

    Gene3Di3.40.50.1220. 1 hit.
    InterProiIPR029035. DHS-like_NAD/FAD-binding_dom.
    IPR003000. Sirtuin.
    IPR026590. Ssirtuin_cat_dom.
    [Graphical view]
    PANTHERiPTHR11085. PTHR11085. 1 hit.
    PfamiPF02146. SIR2. 1 hit.
    [Graphical view]
    SUPFAMiSSF52467. SSF52467. 1 hit.
    PROSITEiPS50305. SIRTUIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    D3YVQ5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVGAGISTPS GIPDFRSPGS GLYSNLQQYD IPYPEAIFEL GFFFHNPKPF    50
    FMLAKELYPG HYRPNVTHYF LRLLHDKELL LRLYTQNIDG LERASGIPAS 100
    KLVEAHGTFV TATCTVCRRS FPGEDIWVEP FASLSEAVQK SVPRLLINRD 150
    LVGPFVLSPR RKDVVQLGDV VHGVERLVDL LG 182
    Length:182
    Mass (Da):20,384
    Last modified:April 20, 2010 - v1
    Checksum:i9E513E9211121F43
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei182 – 1821Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC107815 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000137024; ENSMUSP00000114247; ENSMUSG00000025486.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC107815 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali D3YVQ5.
    SMRi D3YVQ5. Positions 1-182.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000137024 ; ENSMUSP00000114247 ; ENSMUSG00000025486 .

    Organism-specific databases

    MGIi MGI:1927665. Sirt3.

    Phylogenomic databases

    GeneTreei ENSGT00740000115546.
    HOGENOMi HOG000085952.

    Miscellaneous databases

    ChiTaRSi SIRT3. mouse.
    NextBioi 35548917.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi D3YVQ5.
    Bgeei D3YVQ5.

    Family and domain databases

    Gene3Di 3.40.50.1220. 1 hit.
    InterProi IPR029035. DHS-like_NAD/FAD-binding_dom.
    IPR003000. Sirtuin.
    IPR026590. Ssirtuin_cat_dom.
    [Graphical view ]
    PANTHERi PTHR11085. PTHR11085. 1 hit.
    Pfami PF02146. SIR2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52467. SSF52467. 1 hit.
    PROSITEi PS50305. SIRTUIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiD3YVQ5_MOUSE
    AccessioniPrimary (citable) accession number: D3YVQ5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 20, 2010
    Last sequence update: April 20, 2010
    Last modified: October 1, 2014
    This is version 34 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3