ID   D3YVB1_MOUSE            Unreviewed;       190 AA.
AC   D3YVB1;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   27-MAR-2024, entry version 73.
DE   RecName: Full=Vezatin {ECO:0000256|ARBA:ARBA00018125};
DE   Flags: Fragment;
GN   Name=Vezt {ECO:0000313|Ensembl:ENSMUSP00000114550.2,
GN   ECO:0000313|MGI:MGI:2143698};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000114550.2, ECO:0000313|Proteomes:UP000000589};
RN   [1] {ECO:0000313|Ensembl:ENSMUSP00000114550.2, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000114550.2,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2] {ECO:0000313|Ensembl:ENSMUSP00000114550.2}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000114550.2};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell junction, adherens junction
CC       {ECO:0000256|ARBA:ARBA00004536}. Cell membrane
CC       {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}. Nucleus
CC       {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the vezatin family.
CC       {ECO:0000256|ARBA:ARBA00007245}.
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DR   AlphaFoldDB; D3YVB1; -.
DR   MaxQB; D3YVB1; -.
DR   PeptideAtlas; D3YVB1; -.
DR   ProteomicsDB; 346939; -.
DR   Antibodypedia; 1345; 73 antibodies from 23 providers.
DR   Ensembl; ENSMUST00000123201.8; ENSMUSP00000114550.2; ENSMUSG00000036099.17.
DR   AGR; MGI:2143698; -.
DR   MGI; MGI:2143698; Vezt.
DR   VEuPathDB; HostDB:ENSMUSG00000036099; -.
DR   GeneTree; ENSGT00390000003290; -.
DR   ChiTaRS; Vezt; mouse.
DR   Proteomes; UP000000589; Chromosome 10.
DR   Bgee; ENSMUSG00000036099; Expressed in superior cervical ganglion and 239 other cell types or tissues.
DR   ExpressionAtlas; D3YVB1; baseline and differential.
DR   GO; GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0017022; F:myosin binding; IEA:InterPro.
DR   GO; GO:0098609; P:cell-cell adhesion; IEA:InterPro.
DR   InterPro; IPR026859; Myosin-bd.
DR   InterPro; IPR026858; Vezatin.
DR   PANTHER; PTHR15989; VEZATIN; 1.
DR   PANTHER; PTHR15989:SF5; VEZATIN; 1.
DR   Pfam; PF12632; Vezatin; 1.
PE   1: Evidence at protein level;
KW   Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Proteomics identification {ECO:0007829|EPD:D3YVB1,
KW   ECO:0007829|MaxQB:D3YVB1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          144..190
FT                   /note="Myosin-binding"
FT                   /evidence="ECO:0000259|Pfam:PF12632"
FT   NON_TER         190
FT                   /evidence="ECO:0000313|Ensembl:ENSMUSP00000114550.2"
SQ   SEQUENCE   190 AA;  21314 MW;  D8554A13DDAAD437 CRC64;
     MTPEFDEEVV FENSPLYQYL QDLGHTDFEI CSSSSPKPEK CLTTEGPQPP PTRVLQRQGI
     LLKLTETIKS WTFSSQHSKK DDLLHKLDTG FRLDSLHTIL QQEVLLQEDV ELLELLDASI
     LSAGQPQQES GHLPTLCSLA TPNTWVSAAC SFNKAAQHPG QHLIGLRKAV YRTVRANFQA
     ARLATLYMLK
//