D3YV89 (D3YV89_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Protein Mmp27 Ensembl ENSMUSP00000091423 Ensembl ENSMUSP00000117469

Gene names

Name:

Mmp27 Ensembl ENSMUSP00000091423 Ensembl ENSMUSP00000117469 MGI 3039232

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000091423

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	551 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities	Contains 4 hemopexin-like domains. SAAS SAAS006026
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000091423 Ensembl ENSMUSP00000117469

Ontologies

Keywords
Domain	Repeat SAAS SAAS006026
Ligand	Calcium SAAS SAAS006026 Metal-binding SAAS SAAS006026 Zinc SAAS SAAS006026
Molecular function	Hydrolase Metalloprotease SAAS SAAS018486 Protease
PTM	Disulfide bond SAAS SAAS006026
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	extracellular matrix Inferred from electronic annotation. Source: InterPro
Molecular_function	calcium ion binding Inferred from electronic annotation. Source: InterPro metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	258	1	By similarity PIRSR PIRSR001191-1
Experimental info
	Non-terminal residue	551	1	Ensembl ENSMUSP00000117469

Sequences

	Sequence		Length	Mass (Da)
	D3YV89 [UniParc]. Last modified April 20, 2010. Version 1. Checksum: DCB1EB235899FD0A	FASTA	551	62,544
	10 20 30 40 50 60 MPYKQKQALT EETGMKCLLS LMVNFITLSA AFPPDRKDKN EENNQLAQAY LNQFYSLEIE 70 80 90 100 110 120 GSHFVQSKNR SLFDGKLREM QAFFGLTVTG KLDSDTLAIM KVPRCGVPDV GQYGYTLPGW 130 140 150 160 170 180 RKYSLTYRIM NYTPDMTPAD VDEAIQKALQ VWSKVTPLTF TRISKGVADI MIAFRTGGKA 190 200 210 220 230 240 CSEGSDFFED HRELTYLPIN CLSVHGWCPR HFDGPLGVLG HAFPPGLGLG GDTHFDEDET 250 260 270 280 290 300 WIAKDGEGFN LFLVAAHEFG HSLGLSHSND QTALMFPNYI SLDPSKYPLS QDDIDGIQSI 310 320 330 340 350 360 YGSPPKVTTK PSGNSEPHAC DPTLTFDAIT TFRREVMFFK GRHLWRVYSD IAGAEFEFID 370 380 390 400 410 420 SFWPSLPADL QAAYESPRDE LLVFKDENFW VIRGYSVLPG YPKSIHTLGF PRRVKKIDAA 430 440 450 460 470 480 VCDHDTRKTF FFVGIWCWRY DEMAQAMDRG FPQRIIKCFP GIRLRVDAVF QHNGFLYFFH 490 500 510 520 530 540 GSRQFEYDMK AKNITQVIKT NSWFLCNEPL NASFNVSVKG KANSIGTVIL HHKRLSLLTF 550 SIVHVLTKTY N

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000091423 Ensembl ENSMUSP00000117469.
[2]	Ensembl Submitted (MAY-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000091423.
[3]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000117469.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC115689 Genomic DNA. No translation available.
IPI	IPI00355562.
RefSeq	NP_001025460.1. NM_001030289.1.
UniGene	Mm.334940.
3D structure databases
SMR	D3YV89. Positions 46-504.
ModBase	Search...
Protocols and materials databases
DNASU	234911.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000093896; ENSMUSP00000091423; ENSMUSG00000070323. ENSMUST00000151853; ENSMUSP00000117469; ENSMUSG00000070323.
GeneID	234911.
KEGG	mmu:234911.
UCSC	uc009ocs.1. mouse.
Organism-specific databases
CTD	64066.
MGI	MGI:3039232. Mmp27.
Phylogenomic databases
GeneTree	ENSGT00630000089491.
HOGENOM	HOG000217927.
KO	K08005.
OMA	HACDPDL.
OrthoDB	EOG42BX8B.
Family and domain databases
Gene3D	2.110.10.10. 1 hit. 3.40.390.10. 1 hit.
InterPro	IPR000585. Hemopexin-like_dom. IPR018487. Hemopexin-like_repeat. IPR018486. Hemopexin_CS. IPR024079. MetalloPept_cat_dom. IPR001818. Pept_M10_metallopeptidase. IPR021190. Pept_M10A. IPR016293. Pept_M10A_Metazoans. IPR021158. Pept_M10A_Zn_BS. IPR006026. Peptidase_Metallo. IPR002477. Peptidoglycan-bd-like. [Graphical view]
Pfam	PF00045. Hemopexin. 3 hits. PF00413. Peptidase_M10. 1 hit. PF01471. PG_binding_1. 1 hit. [Graphical view]
PIRSF	PIRSF001191. Peptidase_M10A_matrix. 1 hit.
PRINTS	PR00138. MATRIXIN.
SMART	SM00120. HX. 4 hits. SM00235. ZnMc. 1 hit. [Graphical view]
SUPFAM	SSF50923. Hemopexin. 1 hit. SSF47090. PGBD_like. 1 hit.
PROSITE	PS00546. CYSTEINE_SWITCH. 1 hit. PS00024. HEMOPEXIN. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	382432.
SOURCE	Search...

Entry information

Entry name

D3YV89_MOUSE

Accession

Primary (citable) accession number: D3YV89

Entry history

Integrated into UniProtKB/TrEMBL:	April 20, 2010
Last sequence update:	April 20, 2010
Last modified:	May 1, 2013
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)