ID   D3YV82_MOUSE            Unreviewed;       194 AA.
AC   D3YV82;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   27-MAR-2024, entry version 88.
DE   SubName: Full=Zinc finger protein 715 {ECO:0000313|Ensembl:ENSMUSP00000114600.2};
DE   Flags: Fragment;
GN   Name=Zfp715 {ECO:0000313|Ensembl:ENSMUSP00000114600.2,
GN   ECO:0000313|MGI:MGI:1917180};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000114600.2, ECO:0000313|Proteomes:UP000000589};
RN   [1] {ECO:0000313|Ensembl:ENSMUSP00000114600.2, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000114600.2,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2] {ECO:0000313|Ensembl:ENSMUSP00000114600.2}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000114600.2};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC       family. {ECO:0000256|ARBA:ARBA00006991}.
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DR   AlphaFoldDB; D3YV82; -.
DR   SMR; D3YV82; -.
DR   MaxQB; D3YV82; -.
DR   ProteomicsDB; 315995; -.
DR   Ensembl; ENSMUST00000139061.2; ENSMUSP00000114600.2; ENSMUSG00000012640.17.
DR   AGR; MGI:1917180; -.
DR   MGI; MGI:1917180; Zfp715.
DR   VEuPathDB; HostDB:ENSMUSG00000012640; -.
DR   GeneTree; ENSGT01100000263552; -.
DR   HOGENOM; CLU_1405495_0_0_1; -.
DR   OMA; HEITHTT; -.
DR   ChiTaRS; Zfp715; mouse.
DR   Proteomes; UP000000589; Chromosome 7.
DR   Bgee; ENSMUSG00000012640; Expressed in otolith organ and 228 other cell types or tissues.
DR   ExpressionAtlas; D3YV82; baseline and differential.
DR   GO; GO:0005829; C:cytosol; ISO:MGI.
DR   GO; GO:0005730; C:nucleolus; ISO:MGI.
DR   GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; ISO:MGI.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR   GO; GO:0001227; F:DNA-binding transcription repressor activity, RNA polymerase II-specific; ISO:MGI.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; ISO:MGI.
DR   GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; ISO:MGI.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; ISO:MGI.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   CDD; cd07765; KRAB_A-box; 1.
DR   Gene3D; 6.10.140.140; -; 1.
DR   InterPro; IPR001909; KRAB.
DR   InterPro; IPR036051; KRAB_dom_sf.
DR   PANTHER; PTHR23232; KRAB DOMAIN C2H2 ZINC FINGER; 1.
DR   PANTHER; PTHR23232:SF132; ZINC FINGER PROTEIN 939; 1.
DR   Pfam; PF01352; KRAB; 1.
DR   SMART; SM00349; KRAB; 1.
DR   SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR   PROSITE; PS50805; KRAB; 1.
PE   1: Evidence at protein level;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Proteomics identification {ECO:0007829|EPD:D3YV82,
KW   ECO:0007829|MaxQB:D3YV82};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT   DOMAIN          48..119
FT                   /note="KRAB"
FT                   /evidence="ECO:0000259|PROSITE:PS50805"
FT   REGION          1..39
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         194
FT                   /evidence="ECO:0000313|Ensembl:ENSMUSP00000114600.2"
SQ   SEQUENCE   194 AA;  21826 MW;  E4B9CC713BBCE4B4 CRC64;
     MTLEGFGFAT KKTSRTEDRG AMAADPNFQQ KSQPLGAEEQ PESCERWMSF EDVTVNFSQE
     EWQHLDSAQR CLYQEVMLEI YSHLLAVGYS IPSPGVIFRM EKGKEAQTAK AEFPGQRCQE
     KSGNDTLPQK ASGKTSVYSN VASEVTRDGS WCSLLQELWQ GADITKRGQQ NQILLFPPGS
     FLKKTLSKNS DHEY
//