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D3YUY5

- D3YUY5_MOUSE

UniProt

D3YUY5 - D3YUY5_MOUSE

Protein
Submitted name:

Serine/threonine-protein kinase receptor R3

Gene

Acvrl1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. activin receptor activity, type I Source: Ensembl
    2. ATP binding Source: Ensembl
    3. protein binding Source: MGI
    4. receptor signaling protein serine/threonine kinase activity Source: Ensembl
    5. transforming growth factor beta receptor activity, type I Source: Ensembl

    GO - Biological processi

    1. angiogenesis Source: MGI
    2. blood vessel morphogenesis Source: MGI
    3. BMP signaling pathway Source: MGI
    4. cellular response to BMP stimulus Source: Ensembl
    5. endothelial tube morphogenesis Source: Ensembl
    6. in utero embryonic development Source: MGI
    7. negative regulation of blood vessel endothelial cell migration Source: Ensembl
    8. negative regulation of cell growth Source: Ensembl
    9. negative regulation of cell proliferation Source: Ensembl
    10. negative regulation of DNA biosynthetic process Source: Ensembl
    11. negative regulation of focal adhesion assembly Source: Ensembl
    12. positive regulation of angiogenesis Source: MGI
    13. positive regulation of BMP signaling pathway Source: Ensembl
    14. positive regulation of pathway-restricted SMAD protein phosphorylation Source: Ensembl
    15. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
    16. protein heterooligomerization Source: Ensembl
    17. regulation of blood pressure Source: Ensembl
    18. transforming growth factor beta receptor signaling pathway Source: MGI
    19. wound healing, spreading of epidermal cells Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Serine/threonine-protein kinase receptor R3Imported
    Gene namesi
    Name:Acvrl1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 15

    Organism-specific databases

    MGIiMGI:1338946. Acvrl1.

    Subcellular locationi

    GO - Cellular componenti

    1. cell surface Source: Ensembl
    2. dendrite Source: Ensembl
    3. integral component of plasma membrane Source: Ensembl
    4. neuronal cell body Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiD3YUY5.
    BgeeiD3YUY5.

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00730000110868.

    Family and domain databases

    InterProiIPR000333. TGFB_receptor.
    [Graphical view]
    PANTHERiPTHR23255. PTHR23255. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    D3YUY5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTLGSFRRGL LMLSVAFGLT RGDLAKPSKL VNCTCESPHC KRPFCQGSWC   50
    TVVLVREQGR HPQVYRGCGS LNQELC 76
    Length:76
    Mass (Da):8,429
    Last modified:April 20, 2010 - v1
    Checksum:iCA4A2348973AA4AA
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei76 – 761Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC104834 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000124151; ENSMUSP00000114829; ENSMUSG00000000530.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC104834 Genomic DNA. No translation available.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000124151 ; ENSMUSP00000114829 ; ENSMUSG00000000530 .

    Organism-specific databases

    MGIi MGI:1338946. Acvrl1.

    Phylogenomic databases

    GeneTreei ENSGT00730000110868.

    Miscellaneous databases

    NextBioi 35548736.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi D3YUY5.
    Bgeei D3YUY5.

    Family and domain databases

    InterProi IPR000333. TGFB_receptor.
    [Graphical view ]
    PANTHERi PTHR23255. PTHR23255. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiD3YUY5_MOUSE
    AccessioniPrimary (citable) accession number: D3YUY5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 20, 2010
    Last sequence update: April 20, 2010
    Last modified: October 1, 2014
    This is version 34 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3