ID   D3YUI3_MOUSE            Unreviewed;       233 AA.
AC   D3YUI3;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   27-MAR-2024, entry version 73.
DE   SubName: Full=PZP, alpha-2-macroglobulin like {ECO:0000313|Ensembl:ENSMUSP00000120114.2};
DE   Flags: Fragment;
GN   Name=Pzp {ECO:0000313|Ensembl:ENSMUSP00000120114.2,
GN   ECO:0000313|MGI:MGI:87854};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000120114.2, ECO:0000313|Proteomes:UP000000589};
RN   [1] {ECO:0000313|Ensembl:ENSMUSP00000120114.2, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000120114.2,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2] {ECO:0007829|PubMed:21183079}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
RN   [3] {ECO:0000313|Ensembl:ENSMUSP00000120114.2}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000120114.2};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; D3YUI3; -.
DR   SMR; D3YUI3; -.
DR   jPOST; D3YUI3; -.
DR   MaxQB; D3YUI3; -.
DR   PeptideAtlas; D3YUI3; -.
DR   ProteomicsDB; 359658; -.
DR   Ensembl; ENSMUST00000143664.2; ENSMUSP00000120114.2; ENSMUSG00000030359.15.
DR   AGR; MGI:87854; -.
DR   MGI; MGI:87854; Pzp.
DR   VEuPathDB; HostDB:ENSMUSG00000030359; -.
DR   GeneTree; ENSGT00940000163775; -.
DR   HOGENOM; CLU_995846_0_0_1; -.
DR   ChiTaRS; Pzp; mouse.
DR   Proteomes; UP000000589; Chromosome 6.
DR   Bgee; ENSMUSG00000030359; Expressed in left lobe of liver and 61 other cell types or tissues.
DR   ExpressionAtlas; D3YUI3; baseline and differential.
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; IEA:InterPro.
DR   Gene3D; 2.60.40.1930; -; 1.
DR   InterPro; IPR002890; MG2.
DR   PANTHER; PTHR11412; MACROGLOBULIN / COMPLEMENT; 1.
DR   PANTHER; PTHR11412:SF116; PREGNANCY ZONE PROTEIN; 1.
DR   Pfam; PF01835; MG2; 1.
PE   1: Evidence at protein level;
KW   Proteomics identification {ECO:0007829|MaxQB:D3YUI3,
KW   ECO:0007829|PeptideAtlas:D3YUI3};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           25..233
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003052921"
FT   DOMAIN          127..212
FT                   /note="Macroglobulin"
FT                   /evidence="ECO:0000259|Pfam:PF01835"
FT   NON_TER         233
FT                   /evidence="ECO:0000313|Ensembl:ENSMUSP00000120114.2"
SQ   SEQUENCE   233 AA;  26446 MW;  09CDEA9D48EC270E CRC64;
     MRRNQLPTPA FLLLFLLLPR DATTATAKPQ YVVLVPSEVY SGVPEKACVS LNHVNETVML
     SLTLEYAMQQ TKLLTDQAVD KDSFYCSPFT ISGSPLPYTF ITVEIKGPTQ RFIKKKSIQI
     IKAESPVFVQ TDKPIYKPGQ IVKFRVVSVD ISFRPLNETT PKRNRIFQWQ NIHLAGGLHQ
     LSFPLSVEPA LGIYKVVVQK DSGKKIEHSF EVKEYVLPKF EVIIKMQKTM AFL
//