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Protein
Submitted name:

Alpha-2-macroglobulin

Gene

Pzp

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. endopeptidase inhibitor activity Source: MGI

GO - Biological processi

  1. embryo implantation Source: MGI
  2. negative regulation of endopeptidase activity Source: GOC
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha-2-macroglobulinImported
Gene namesi
Name:PzpImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 6

Organism-specific databases

MGIiMGI:87854. Pzp.

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: MGI
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiD3YUI3.

Expressioni

Gene expression databases

BgeeiD3YUI3.
ExpressionAtlasiD3YUI3. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliD3YUI3.
SMRiD3YUI3. Positions 31-231.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000118982.

Family and domain databases

InterProiIPR002890. A2M_N.
[Graphical view]
PfamiPF01835. A2M_N. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

D3YUI3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRRNQLPTPA FLLLFLLLPR DATTATAKPQ YVVLVPSEVY SGVPEKACVS
60 70 80 90 100
LNHVNETVML SLTLEYAMQQ TKLLTDQAVD KDSFYCSPFT ISGSPLPYTF
110 120 130 140 150
ITVEIKGPTQ RFIKKKSIQI IKAESPVFVQ TDKPIYKPGQ IVKFRVVSVD
160 170 180 190 200
ISFRPLNETT PKRNRIFQWQ NIHLAGGLHQ LSFPLSVEPA LGIYKVVVQK
210 220 230
DSGKKIEHSF EVKEYVLPKF EVIIKMQKTM AFL
Length:233
Mass (Da):26,446
Last modified:April 20, 2010 - v1
Checksum:i09CDEA9D48EC270E
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei233 – 2331Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC123060 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000143664; ENSMUSP00000120114; ENSMUSG00000030359.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC123060 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliD3YUI3.
SMRiD3YUI3. Positions 31-231.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiD3YUI3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000143664; ENSMUSP00000120114; ENSMUSG00000030359.

Organism-specific databases

MGIiMGI:87854. Pzp.

Phylogenomic databases

GeneTreeiENSGT00760000118982.

Miscellaneous databases

NextBioi35548626.
SOURCEiSearch...

Gene expression databases

BgeeiD3YUI3.
ExpressionAtlasiD3YUI3. baseline and differential.

Family and domain databases

InterProiIPR002890. A2M_N.
[Graphical view]
PfamiPF01835. A2M_N. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiD3YUI3_MOUSE
AccessioniPrimary (citable) accession number: D3YUI3
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: January 7, 2015
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.