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Protein
Submitted name:

F-box/WD repeat-containing protein 7

Gene

Fbxw7

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Names & Taxonomyi

Protein namesi
Submitted name:
F-box/WD repeat-containing protein 7Imported
Gene namesi
Name:Fbxw7Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 3

Organism-specific databases

MGIiMGI:1354695. Fbxw7.

PTM / Processingi

Proteomic databases

PaxDbiD3YUA8.
PRIDEiD3YUA8.

Expressioni

Gene expression databases

BgeeiENSMUSG00000028086.
ExpressionAtlasiD3YUA8. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000103305.

Structurei

3D structure databases

ProteinModelPortaliD3YUA8.
SMRiD3YUA8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini160 – 206F-boxInterPro annotationAdd BLAST47
Domaini258 – 541WD_REPEATS_REGIONInterPro annotationAdd BLAST284
Repeati273 – 298WDPROSITE-ProRule annotationAdd BLAST26
Repeati299 – 338WDPROSITE-ProRule annotationAdd BLAST40
Repeati339 – 378WDPROSITE-ProRule annotationAdd BLAST40
Repeati379 – 418WDPROSITE-ProRule annotationAdd BLAST40
Repeati419 – 458WDPROSITE-ProRule annotationAdd BLAST40
Repeati459 – 498WDPROSITE-ProRule annotationAdd BLAST40
Repeati502 – 541WDPROSITE-ProRule annotationAdd BLAST40

Keywords - Domaini

WD repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0274. Eukaryota.
ENOG410XRWX. LUCA.
GeneTreeiENSGT00760000119106.
HOGENOMiHOG000236264.

Family and domain databases

Gene3Di2.130.10.10. 2 hits.
InterProiView protein in InterPro
IPR001810. F-box_dom.
IPR020472. G-protein_beta_WD-40_rep.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
PfamiView protein in Pfam
PF12937. F-box-like. 1 hit.
PF00400. WD40. 7 hits.
PRINTSiPR00320. GPROTEINBRPT.
SMARTiView protein in SMART
SM00256. FBOX. 1 hit.
SM00320. WD40. 8 hits.
SUPFAMiSSF50978. SSF50978. 1 hit.
SSF81383. SSF81383. 1 hit.
PROSITEiView protein in PROSITE
PS50181. FBOX. 1 hit.
PS00678. WD_REPEATS_1. 5 hits.
PS50082. WD_REPEATS_2. 7 hits.
PS50294. WD_REPEATS_REGION. 1 hit.

Sequencei

Sequence statusi: Complete.

D3YUA8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKPGKAPVN HGLVPVDLKS AKDPLPHQTV MKIFSISIIA QGLPFCRRRM
60 70 80 90 100
KRKLDHGSEV RSFSLGKKPC KVSDYTSTTG LVPCSATPTT FGDLRAANGQ
110 120 130 140 150
GQQRRRITSV QPPTGLQEWL KMFQSWSGPE KLLALDELID SCEPTQVKHM
160 170 180 190 200
MQVIEPQFQR DFISLLPKEL ALYVLSFLEP KDLLQAAQTC RYWRILAEDN
210 220 230 240 250
LLWREKCKEE GIDEPLHIKR RKIIKPGFIH SPWKSAYIRQ HRIDTNWRRG
260 270 280 290 300
ELKSPKVLKG HDDHVITCLQ FCGNRIVSGS DDNTLKVWSA VTGKCLRTLV
310 320 330 340 350
GHTGGVWSSQ MRDNIIISGS TDRTLKVWNA ETGECIHTLY GHTSTVRCMH
360 370 380 390 400
LHEKRVVSGS RDATLRVWDI ETGQCLHVLM GHVAAVRCVQ YDGRRVVSGA
410 420 430 440 450
YDFMVKVWDP ETETCLHTLQ GHTNRVYSLQ FDGIHVVSGS LDTSIRVWDV
460 470 480 490 500
ETGNCIHTLT GHQSLTSGME LKDNILVSGN ADSTVKIWDI KTGQCLQTLQ
510 520 530 540 550
GPSKHQSAVT CLQFNKNFVI TSSDDGTVKL WDLKTGEFIR NLVTLESGGS
560 570 580
GGVVWRIRAS NTKLVCAVGS RNGTEETKLL VLDFDVDMK
Length:589
Mass (Da):66,035
Last modified:April 20, 2010 - v1
Checksum:iF1C0A15DC12924F4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124496 Genomic DNA. No translation available.
AC158583 Genomic DNA. No translation available.
RefSeqiXP_006501721.1. XM_006501658.2.
UniGeneiMm.196475.

Genome annotation databases

EnsembliENSMUST00000107675; ENSMUSP00000103302; ENSMUSG00000028086.
GeneIDi50754.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124496 Genomic DNA. No translation available.
AC158583 Genomic DNA. No translation available.
RefSeqiXP_006501721.1. XM_006501658.2.
UniGeneiMm.196475.

3D structure databases

ProteinModelPortaliD3YUA8.
SMRiD3YUA8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000103305.

Proteomic databases

PaxDbiD3YUA8.
PRIDEiD3YUA8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000107675; ENSMUSP00000103302; ENSMUSG00000028086.
GeneIDi50754.

Organism-specific databases

CTDi55294.
MGIiMGI:1354695. Fbxw7.

Phylogenomic databases

eggNOGiKOG0274. Eukaryota.
ENOG410XRWX. LUCA.
GeneTreeiENSGT00760000119106.
HOGENOMiHOG000236264.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000028086.
ExpressionAtlasiD3YUA8. baseline and differential.

Family and domain databases

Gene3Di2.130.10.10. 2 hits.
InterProiView protein in InterPro
IPR001810. F-box_dom.
IPR020472. G-protein_beta_WD-40_rep.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
PfamiView protein in Pfam
PF12937. F-box-like. 1 hit.
PF00400. WD40. 7 hits.
PRINTSiPR00320. GPROTEINBRPT.
SMARTiView protein in SMART
SM00256. FBOX. 1 hit.
SM00320. WD40. 8 hits.
SUPFAMiSSF50978. SSF50978. 1 hit.
SSF81383. SSF81383. 1 hit.
PROSITEiView protein in PROSITE
PS50181. FBOX. 1 hit.
PS00678. WD_REPEATS_1. 5 hits.
PS50082. WD_REPEATS_2. 7 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiD3YUA8_MOUSE
AccessioniPrimary (citable) accession number: D3YUA8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: May 10, 2017
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.