Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Insulin-like growth factor-binding protein 2

Gene

Igfbp2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Insulin-like growth factor-binding protein 2Imported
Gene namesi
Name:Igfbp2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:96437 Igfbp2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

MaxQBiD3YU40
PeptideAtlasiD3YU40

Expressioni

Gene expression databases

BgeeiENSMUSG00000039323
ExpressionAtlasiD3YU40 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliD3YU40
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini57 – 139Thyroglobulin type-1InterPro annotationAdd BLAST83

Phylogenomic databases

eggNOGiENOG410IHUR Eukaryota
ENOG4111GWQ LUCA
GeneTreeiENSGT00550000074457
HOGENOMiHOG000185884

Family and domain databases

CDDicd00191 TY, 1 hit
Gene3Di4.10.800.10, 1 hit
InterProiView protein in InterPro
IPR012210 IGFBP-2
IPR009168 IGFBP1-6
IPR022321 IGFBP_1-6_chordata
IPR000716 Thyroglobulin_1
IPR036857 Thyroglobulin_1_sf
PANTHERiPTHR11551 PTHR11551, 1 hit
PfamiView protein in Pfam
PF00086 Thyroglobulin_1, 1 hit
PRINTSiPR01976 IGFBPFAMILY
PR01978 IGFBPFAMILY2
SMARTiView protein in SMART
SM00211 TY, 1 hit
SUPFAMiSSF57610 SSF57610, 1 hit
PROSITEiView protein in PROSITE
PS00484 THYROGLOBULIN_1_1, 1 hit
PS51162 THYROGLOBULIN_1_2, 1 hit

Sequencei

Sequence statusi: Complete.

D3YU40-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNMLGGGSSA GRKPLKSGMK ELAVFREKVN EQHRQMGKGA KHLSLEEPKK
60 70 80 90 100
LRPPPARTPC QQELDQVLER ISTMRLPDDR GPLEHLYSLH IPNCDKHGRY
110 120 130 140 150
NLKQCKMSLN GQRGECWCVN PNTGKPIQGA PTIRGDPECH LFYNEQQETG

GAHAQSVQ
Length:158
Mass (Da):17,706
Last modified:April 20, 2010 - v1
Checksum:iE9399437D961AD28
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC115870 Genomic DNA No translation available.
AC121498 Genomic DNA No translation available.
RefSeqiNP_001297588.1, NM_001310659.1
UniGeneiMm.141936

Genome annotation databases

EnsembliENSMUST00000120564; ENSMUSP00000112706; ENSMUSG00000039323
GeneIDi16008

Similar proteinsi

Entry informationi

Entry nameiD3YU40_MOUSE
AccessioniPrimary (citable) accession number: D3YU40
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: April 25, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health