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D3YU40

- D3YU40_MOUSE

UniProt

D3YU40 - D3YU40_MOUSE

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Protein
Submitted name:

Insulin-like growth factor-binding protein 2

Gene

Igfbp2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. insulin-like growth factor binding Source: MGI

GO - Biological processi

  1. aging Source: Ensembl
  2. cellular response to hormone stimulus Source: Ensembl
  3. female pregnancy Source: Ensembl
  4. positive regulation of activated T cell proliferation Source: Ensembl
  5. response to drug Source: Ensembl
  6. response to estradiol Source: Ensembl
  7. response to glucocorticoid Source: Ensembl
  8. response to lithium ion Source: Ensembl
  9. response to mechanical stimulus Source: Ensembl
  10. response to nutrient Source: Ensembl
  11. response to retinoic acid Source: Ensembl
  12. signal transduction Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Insulin-like growth factor-binding protein 2Imported
Gene namesi
Name:Igfbp2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 1

Organism-specific databases

MGIiMGI:96437. Igfbp2.

Subcellular locationi

GO - Cellular componenti

  1. apical plasma membrane Source: Ensembl
  2. cytoplasmic vesicle Source: Ensembl
  3. extracellular space Source: MGI
  4. extracellular vesicular exosome Source: Ensembl
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiD3YU40.
ExpressionAtlasiD3YU40. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliD3YU40.
SMRiD3YU40. Positions 53-158.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00550000074457.
HOGENOMiHOG000185884.

Family and domain databases

Gene3Di4.10.800.10. 1 hit.
InterProiIPR012210. IGFBP-2.
IPR009168. IGFBP1-6.
IPR022321. IGFBP_1-6_chordata.
IPR000716. Thyroglobulin_1.
[Graphical view]
PANTHERiPTHR11551. PTHR11551. 1 hit.
PTHR11551:SF5. PTHR11551:SF5. 1 hit.
PfamiPF00086. Thyroglobulin_1. 1 hit.
[Graphical view]
PRINTSiPR01976. IGFBPFAMILY.
PR01978. IGFBPFAMILY2.
SMARTiSM00211. TY. 1 hit.
[Graphical view]
SUPFAMiSSF57610. SSF57610. 1 hit.
PROSITEiPS00484. THYROGLOBULIN_1_1. 1 hit.
PS51162. THYROGLOBULIN_1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3YU40-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNMLGGGSSA GRKPLKSGMK ELAVFREKVN EQHRQMGKGA KHLSLEEPKK
60 70 80 90 100
LRPPPARTPC QQELDQVLER ISTMRLPDDR GPLEHLYSLH IPNCDKHGRY
110 120 130 140 150
NLKQCKMSLN GQRGECWCVN PNTGKPIQGA PTIRGDPECH LFYNEQQETG

GAHAQSVQ
Length:158
Mass (Da):17,706
Last modified:April 20, 2010 - v1
Checksum:iE9399437D961AD28
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC115870 Genomic DNA. No translation available.
AC121498 Genomic DNA. No translation available.
RefSeqiXP_006495770.1. XM_006495707.1.
UniGeneiMm.141936.

Genome annotation databases

EnsembliENSMUST00000120564; ENSMUSP00000112706; ENSMUSG00000039323.
GeneIDi16008.
KEGGimmu:16008.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC115870 Genomic DNA. No translation available.
AC121498 Genomic DNA. No translation available.
RefSeqi XP_006495770.1. XM_006495707.1.
UniGenei Mm.141936.

3D structure databases

ProteinModelPortali D3YU40.
SMRi D3YU40. Positions 53-158.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000120564 ; ENSMUSP00000112706 ; ENSMUSG00000039323 .
GeneIDi 16008.
KEGGi mmu:16008.

Organism-specific databases

CTDi 3485.
MGIi MGI:96437. Igfbp2.

Phylogenomic databases

GeneTreei ENSGT00550000074457.
HOGENOMi HOG000185884.

Miscellaneous databases

ChiTaRSi IGFBP2. mouse.
NextBioi 35548525.
SOURCEi Search...

Gene expression databases

Bgeei D3YU40.
ExpressionAtlasi D3YU40. baseline and differential.

Family and domain databases

Gene3Di 4.10.800.10. 1 hit.
InterProi IPR012210. IGFBP-2.
IPR009168. IGFBP1-6.
IPR022321. IGFBP_1-6_chordata.
IPR000716. Thyroglobulin_1.
[Graphical view ]
PANTHERi PTHR11551. PTHR11551. 1 hit.
PTHR11551:SF5. PTHR11551:SF5. 1 hit.
Pfami PF00086. Thyroglobulin_1. 1 hit.
[Graphical view ]
PRINTSi PR01976. IGFBPFAMILY.
PR01978. IGFBPFAMILY2.
SMARTi SM00211. TY. 1 hit.
[Graphical view ]
SUPFAMi SSF57610. SSF57610. 1 hit.
PROSITEi PS00484. THYROGLOBULIN_1_1. 1 hit.
PS51162. THYROGLOBULIN_1_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiD3YU40_MOUSE
AccessioniPrimary (citable) accession number: D3YU40
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: October 29, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3