ID   D3YU02_MOUSE            Unreviewed;       297 AA.
AC   D3YU02;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   27-MAR-2024, entry version 97.
DE   SubName: Full=Protein kinase D3 {ECO:0000313|Ensembl:ENSMUSP00000112775.2};
GN   Name=Prkd3 {ECO:0000313|Ensembl:ENSMUSP00000112775.2,
GN   ECO:0000313|MGI:MGI:1922542};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000112775.2, ECO:0000313|Proteomes:UP000000589};
RN   [1] {ECO:0007829|PubMed:17242355}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=17242355; DOI=10.1073/pnas.0609836104;
RA   Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.;
RT   "Large-scale phosphorylation analysis of mouse liver.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007).
RN   [2] {ECO:0000313|Ensembl:ENSMUSP00000112775.2, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000112775.2,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [3] {ECO:0000313|Ensembl:ENSMUSP00000112775.2}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000112775.2};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; D3YU02; -.
DR   SMR; D3YU02; -.
DR   iPTMnet; D3YU02; -.
DR   MaxQB; D3YU02; -.
DR   PeptideAtlas; D3YU02; -.
DR   ProteomicsDB; 355655; -.
DR   Antibodypedia; 14569; 477 antibodies from 37 providers.
DR   Ensembl; ENSMUST00000118991.2; ENSMUSP00000112775.2; ENSMUSG00000024070.16.
DR   UCSC; uc008dpt.1; mouse.
DR   AGR; MGI:1922542; -.
DR   MGI; MGI:1922542; Prkd3.
DR   VEuPathDB; HostDB:ENSMUSG00000024070; -.
DR   GeneTree; ENSGT00950000183024; -.
DR   HOGENOM; CLU_074004_0_0_1; -.
DR   ChiTaRS; Prkd3; mouse.
DR   Proteomes; UP000000589; Chromosome 17.
DR   Bgee; ENSMUSG00000024070; Expressed in rostral migratory stream and 261 other cell types or tissues.
DR   ExpressionAtlas; D3YU02; baseline and differential.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.60.20; -; 2.
DR   InterPro; IPR046349; C1-like_sf.
DR   InterPro; IPR020454; DAG/PE-bd.
DR   InterPro; IPR002219; PE/DAG-bd.
DR   PANTHER; PTHR22968; PROTEIN KINASE C, MU; 1.
DR   PANTHER; PTHR22968:SF26; SERINE_THREONINE-PROTEIN KINASE D3; 1.
DR   Pfam; PF00130; C1_1; 2.
DR   PRINTS; PR00008; DAGPEDOMAIN.
DR   SMART; SM00109; C1; 2.
DR   SUPFAM; SSF57889; Cysteine-rich domain; 2.
DR   PROSITE; PS00479; ZF_DAG_PE_1; 2.
DR   PROSITE; PS50081; ZF_DAG_PE_2; 2.
PE   1: Evidence at protein level;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Proteomics identification {ECO:0007829|EPD:D3YU02,
KW   ECO:0007829|MaxQB:D3YU02};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          50..100
FT                   /note="Phorbol-ester/DAG-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50081"
FT   DOMAIN          167..217
FT                   /note="Phorbol-ester/DAG-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50081"
FT   REGION          233..273
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        248..273
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   297 AA;  33699 MW;  0036967710BC8B69 CRC64;
     MYDKILLFRH DMNSENILQL ITSADEIHEG DLVEVVLSAL ATVEDFQIRP HALYVHSYKA
     PTFCDYCGEM LWGLVRQGLK CEGCGLNYHK RCAFKIPNNC SGVRKRRLSN VSLPGPGLSV
     PRPLQPECVP LLSEESHTHQ EPSKRIPSWS GRPIWMEKMV MCRVKVPHTF AVHSYGRPTI
     CQYCKRLLKG LFRQGMQCKD CKFNCHKRCA SKVPRDCLGE VTFNGEPCSV GTDADMPMDI
     DSSDVNSDGS RGLDDSEEPS PPEDKMFFLD PTDLDVERDE ETVKTIRARK FLNSKLK
//