D3YTK6 (D3YTK6_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
NAD-dependent protein deacetylase sirtuin-3 Ensembl ENSMUSP00000121151

Gene names

Name:

Sirt3 Ensembl ENSMUSP00000121151 MGI 1927665

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000121151

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	258 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000121151

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	membrane Inferred from direct assay PubMed 11056054. Source: MGI mitochondrion Inferred from direct assay PubMed 18614015PubMed 19241369. Source: MGI
Molecular_function	NAD+ binding Inferred from electronic annotation. Source: InterPro NAD-dependent histone deacetylase activity (H3-K14 specific) Inferred from direct assay PubMed 19241369. Source: MGI
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	258	1	Ensembl ENSMUSP00000121151

Sequences

	Sequence		Length	Mass (Da)
	D3YTK6 [UniParc]. Last modified April 5, 2011. Version 2. Checksum: F5983F76F1FA157B	FASTA	258	28,029
	10 20 30 40 50 60 MALDPLGAVV LQSIMALSGR LALAALRLWG PGGGRRPISL CVGASGGFGG GGSSEKKFSL 70 80 90 100 110 120 QDVAELLRTR ACSRVVVMVG AGISTPSGIP DFRSPGSGLY SNLQQYDIPY PEAIFELGFF 130 140 150 160 170 180 FHNPKPFFML AKELYPGHYR PNVTHYFLRL LHDKELLLRL YTQNIDGLER ASGIPASKLV 190 200 210 220 230 240 EAHGTFVTAT CTVCRRSFPG EDIWADVMAD RVPRCPVCTG VVKPDIVFFG EQLPARFLLH 250 MADFALADLL LILGTSLE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000121151.
[2]	Ensembl Submitted (MAY-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000121151.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC107815 Genomic DNA. No translation available.
IPI	IPI00968349.
3D structure databases
ProteinModelPortal	D3YTK6.
SMR	D3YTK6. Positions 57-258.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000147331; ENSMUSP00000121151; ENSMUSG00000025486.
Organism-specific databases
MGI	MGI:1927665. Sirt3.
Phylogenomic databases
GeneTree	ENSGT00680000099776.
HOGENOM	HOG000085952.
Gene expression databases
ArrayExpress	D3YTK6.
Bgee	D3YTK6.
Family and domain databases
Gene3D	3.30.1600.10. 2 hits.
InterPro	IPR003000. Sirtuin. IPR026591. Sirtuin_cat_small_dom. IPR026590. Ssirtuin_cat_dom. [Graphical view]
PANTHER	PTHR11085. PTHR11085. 1 hit.
Pfam	PF02146. SIR2. 1 hit. [Graphical view]
PROSITE	PS50305. SIRTUIN. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	SIRT3. mouse.
NextBio	35548408.
SOURCE	Search...

Entry information

Entry name

D3YTK6_MOUSE

Accession

Primary (citable) accession number: D3YTK6

Entry history

Integrated into UniProtKB/TrEMBL:	April 20, 2010
Last sequence update:	April 5, 2011
Last modified:	April 3, 2013
This is version 27 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)