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Protein
Submitted name:

Pol protein

Gene

pol

Organism
Human immunodeficiency virus 1
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Catalytic activityi

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).SAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionNucleotidyltransferase, RNA-directed DNA polymeraseSAAS annotation, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Pol proteinImported
Gene namesi
Name:polImported
OrganismiHuman immunodeficiency virus 1Imported
Taxonomic identifieri11676 [NCBI]
Taxonomic lineageiVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeLentivirusPrimate lentivirus group
Virus hostiHomo sapiens (Human) [TaxID: 9606]

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini44 – 234Reverse transcriptaseInterPro annotationAdd BLAST191
Domaini434 – 557RNase HInterPro annotationAdd BLAST124

Family and domain databases

Gene3Di3.30.420.10. 1 hit.
InterProiView protein in InterPro
IPR012337. RNaseH-like_dom.
IPR002156. RNaseH_domain.
IPR000477. RT_dom.
IPR010659. RVT_connect.
IPR010661. RVT_thumb.
PfamiView protein in Pfam
PF00075. RNase_H. 1 hit.
PF00078. RVT_1. 1 hit.
PF06815. RVT_connect. 1 hit.
PF06817. RVT_thumb. 1 hit.
SUPFAMiSSF53098. SSF53098. 1 hit.
PROSITEiView protein in PROSITE
PS50879. RNASE_H. 1 hit.
PS50878. RT_POL. 1 hit.

Sequencei

Sequence statusi: Fragment.

D3XIY3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
PISPIETVPV KLKPGMDGPK VKQWPLTEEK IKALVEICTE LEKEGKISKI
60 70 80 90 100
GPENPYNTPV FAIKKKDSTK WRKLVDFREL NKRTQDFWEV QLGIPHPAGL
110 120 130 140 150
KRKKSVTVLD VGDAYFSVPL DEDFRKYTAF TIPSINNETP GIRYQYNVLP
160 170 180 190 200
QGWKGSPAIF QSSMTKILEP FRKQNPDIVI YQYVDDLLVG SDLEIGQHRA
210 220 230 240 250
KIDELRQHLL RWGFYTPDKK HQKEPPFLWM GYELHPDKWT VQPIELPEKD
260 270 280 290 300
SWTVNDIQKL VGKLNWASQI YAGIRVKELC KLLRGTKALT EVVPLTEEAE
310 320 330 340 350
LELAENREIL KEPVHGVYYD PSKELIAEIQ KQGLGQWTYQ IYQEPYKNLK
360 370 380 390 400
TGKYARMRGA HTNDVKQLTE VVQKIATEGI VIWGKTPKFR LPIQKETWEA
410 420 430 440 450
WWTEYWQATW IPEWEFANTP PLVKLWYQLE KEPIEGAETF YVDGAASRET
460 470 480 490 500
KLGKAGYVTD KGRQKVVTLT DTTNQKTELQ AIYLALQDSG VEVNIVTDSQ
510 520 530 540 550
YALGIIQAQP DKSESELVSQ IIEQLIQKEK VYLAWVPAHK GIGGNEQVDK
560 570
LVSAGIRKVL FLDGIDKAQE
Length:570
Mass (Da):65,455
Last modified:April 20, 2010 - v1
Checksum:i84E81F813FAFC8F5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei570Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GU345325 Genomic RNA. Translation: ADC42366.1.

Similar proteinsi

Entry informationi

Entry nameiD3XIY3_9HIV1
AccessioniPrimary (citable) accession number: D3XIY3
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: April 12, 2017
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)