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Protein

Cytochrome b

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.UniRule annotation

Cofactori

hemeUniRule annotationNote: Binds 2 heme groups non-covalently.UniRule annotation

GO - Molecular functioni

  1. electron carrier activity Source: InterPro
  2. metal ion binding Source: UniProtKB-KW
  3. oxidoreductase activity Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Electron transport, Respiratory chainUniRule annotation, Transport

Keywords - Ligandi

HemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome bUniRule annotation
Encoded oniMitochondrionImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrion Source: UniProtKB-KW
  3. respiratory chain Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane, MitochondrionUniRule annotationImported

Expressioni

Gene expression databases

BgeeiD3WZ03.
ExpressionAtlasiD3WZ03. baseline.

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome b family.UniRule annotation

Keywords - Domaini

TransmembraneUniRule annotation

Family and domain databases

InterProiIPR005798. Cyt_b/b6_C.
[Graphical view]
PfamiPF00032. Cytochrom_B_C. 1 hit.
[Graphical view]
SUPFAMiSSF81648. SSF81648. 1 hit.
PROSITEiPS51003. CYTB_CTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

D3WZ03-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30 
VPNKLGGVLA LLLSILILAM IPILHMSKQQ SMMFRP
Length:36
Mass (Da):3,975
Last modified:April 19, 2010 - v1
Checksum:iB9A1CE632FB29A0E
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei36 – 361Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GU186093 Genomic DNA. Translation: ADD23553.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GU186093 Genomic DNA. Translation: ADD23553.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

NextBioi35491046.

Gene expression databases

BgeeiD3WZ03.
ExpressionAtlasiD3WZ03. baseline.

Family and domain databases

InterProiIPR005798. Cyt_b/b6_C.
[Graphical view]
PfamiPF00032. Cytochrom_B_C. 1 hit.
[Graphical view]
SUPFAMiSSF81648. SSF81648. 1 hit.
PROSITEiPS51003. CYTB_CTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Mitochondrial DNA analysis in primary congenital glaucoma."
    Tanwar M., Dada T., Sihota R., Dada R.
    Mol. Vis. 16:518-533(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: P4Imported.

Entry informationi

Entry nameiD3WZ03_HUMAN
AccessioniPrimary (citable) accession number: D3WZ03
Entry historyi
Integrated into UniProtKB/TrEMBL: April 19, 2010
Last sequence update: April 19, 2010
Last modified: January 6, 2015
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.