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D3UWV6

- APHA_XENBS

UniProt

D3UWV6 - APHA_XENBS

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Protein

Class B acid phosphatase

Gene
aphA, XBJ1_0800
Organism
Xenorhabdus bovienii (strain SS-2004)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Dephosphorylates several organic phosphate monoesters. Also has a phosphotransferase activity catalyzing the transfer of low-energy phosphate groups from organic phosphate monoesters to free hydroxyl groups of various organic compounds By similarity.

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.

Cofactori

Binds 1 magnesium ion per subunit By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei69 – 691Nucleophile By similarity
Metal bindingi69 – 691Magnesium By similarity
Active sitei71 – 711Proton donor By similarity
Metal bindingi71 – 711Magnesium; via carbonyl oxygen By similarity
Binding sitei177 – 1771Substrate By similarity
Metal bindingi192 – 1921Magnesium By similarity

GO - Molecular functioni

  1. acid phosphatase activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Magnesium, Metal-binding

Enzyme and pathway databases

BioCyciXBOV406818:GHLH-800-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Class B acid phosphatase (EC:3.1.3.2)
Short name:
CBAP
Gene namesi
Name:aphA
Ordered Locus Names:XBJ1_0800
OrganismiXenorhabdus bovienii (strain SS-2004)
Taxonomic identifieri406818 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeXenorhabdus
ProteomesiUP000002045: Chromosome

Subcellular locationi

Periplasm By similarity

GO - Cellular componenti

  1. outer membrane-bounded periplasmic space Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323 Reviewed predictionAdd
BLAST
Chaini24 – 237214Class B acid phosphatasePRO_0000415230Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.

Structurei

3D structure databases

ProteinModelPortaliD3UWV6.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni137 – 1382Substrate binding By similarity

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000270623.
KOiK03788.

Family and domain databases

Gene3Di3.40.50.1000. 1 hit.
InterProiIPR005519. Acid_phosphat_B.
IPR023214. HAD-like_dom.
IPR010025. HAD-SF_ppase_IIIB_AphA.
[Graphical view]
PfamiPF03767. Acid_phosphat_B. 1 hit.
[Graphical view]
PIRSFiPIRSF017818. Acid_Ptase_B. 1 hit.
SUPFAMiSSF56784. SSF56784. 1 hit.
TIGRFAMsiTIGR01672. AphA. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

D3UWV6-1 [UniParc]FASTAAdd to Basket

« Hide

MRKVTLVFSA IAFAFSLNGV VQAKVQMPES VSSGVTTVEL SQRQAVHWVS    50
VEQIEKSLQD QPPMAIGFDI DDTVLFSSPG FYRGKLKYSP NDNSYLKNPA 100
FWEKMNNEWD EFSMPKQIGI ELVQMHLKRG DNIYFITGRT KTKTETVTKY 150
LQEDLHIPAD KMNVVIFAGD DPGKNNKISW MKEHKLKLYY GDADADIAAA 200
HELNIRGIRI LRASNSSYQP LPKAGRFGEE VVIKSEY 237
Length:237
Mass (Da):26,870
Last modified:April 20, 2010 - v1
Checksum:i5BA5B902EC8351AF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FN667741 Genomic DNA. Translation: CBJ79941.1.
RefSeqiWP_012987374.1. NC_013892.1.
YP_003466735.1. NC_013892.1.

Genome annotation databases

EnsemblBacteriaiCBJ79941; CBJ79941; XBJ1_0800.
GeneIDi8830427.
KEGGixbo:XBJ1_0800.
PATRICi35296696. VBIXenBov95754_0721.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FN667741 Genomic DNA. Translation: CBJ79941.1 .
RefSeqi WP_012987374.1. NC_013892.1.
YP_003466735.1. NC_013892.1.

3D structure databases

ProteinModelPortali D3UWV6.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CBJ79941 ; CBJ79941 ; XBJ1_0800 .
GeneIDi 8830427.
KEGGi xbo:XBJ1_0800.
PATRICi 35296696. VBIXenBov95754_0721.

Phylogenomic databases

HOGENOMi HOG000270623.
KOi K03788.

Enzyme and pathway databases

BioCyci XBOV406818:GHLH-800-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1000. 1 hit.
InterProi IPR005519. Acid_phosphat_B.
IPR023214. HAD-like_dom.
IPR010025. HAD-SF_ppase_IIIB_AphA.
[Graphical view ]
Pfami PF03767. Acid_phosphat_B. 1 hit.
[Graphical view ]
PIRSFi PIRSF017818. Acid_Ptase_B. 1 hit.
SUPFAMi SSF56784. SSF56784. 1 hit.
TIGRFAMsi TIGR01672. AphA. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Xenorhabdus nematophila (strain ATCC 19061 / DSM 3370 / LMG 1036 / NCIB 9965 / AN6)."
    Goodrich-Blair H., Barbazuk B., Bode H.B., Darby C., Du Z., Forst S., Gaudriault S., Goldman B.S., Goodner B., Henkhaus J., Latreille P., Medigue C., Miller N., Norton S., Ogier J.C., Rouy Z., Slater S., Suen G.
    Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SS-2004.

Entry informationi

Entry nameiAPHA_XENBS
AccessioniPrimary (citable) accession number: D3UWV6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 25, 2012
Last sequence update: April 20, 2010
Last modified: September 3, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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