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D3UWV6 (APHA_XENBS) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Class B acid phosphatase

Short name=CBAP
EC=3.1.3.2
Gene names
Name:aphA
Ordered Locus Names:XBJ1_0800
OrganismXenorhabdus bovienii (strain SS-2004) [Complete proteome] [HAMAP]
Taxonomic identifier406818 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeXenorhabdus

Protein attributes

Sequence length237 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Dephosphorylates several organic phosphate monoesters. Also has a phosphotransferase activity catalyzing the transfer of low-energy phosphate groups from organic phosphate monoesters to free hydroxyl groups of various organic compounds By similarity.

Catalytic activity

A phosphate monoester + H2O = an alcohol + phosphate.

Cofactor

Binds 1 magnesium ion per subunit By similarity.

Subunit structure

Homotetramer By similarity.

Subcellular location

Periplasm By similarity.

Sequence similarities

Belongs to the class B bacterial acid phosphatase family.

Ontologies

Keywords
   Cellular componentPeriplasm
   DomainSignal
   LigandMagnesium
Metal-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentouter membrane-bounded periplasmic space

Inferred from electronic annotation. Source: InterPro

   Molecular_functionacid phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-EC

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2323 Potential
Chain24 – 237214Class B acid phosphatase
PRO_0000415230

Regions

Region137 – 1382Substrate binding By similarity

Sites

Active site691Nucleophile By similarity
Active site711Proton donor By similarity
Metal binding691Magnesium By similarity
Metal binding711Magnesium; via carbonyl oxygen By similarity
Metal binding1921Magnesium By similarity
Binding site1771Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
D3UWV6 [UniParc].

Last modified April 20, 2010. Version 1.
Checksum: 5BA5B902EC8351AF

FASTA23726,870
        10         20         30         40         50         60 
MRKVTLVFSA IAFAFSLNGV VQAKVQMPES VSSGVTTVEL SQRQAVHWVS VEQIEKSLQD 

        70         80         90        100        110        120 
QPPMAIGFDI DDTVLFSSPG FYRGKLKYSP NDNSYLKNPA FWEKMNNEWD EFSMPKQIGI 

       130        140        150        160        170        180 
ELVQMHLKRG DNIYFITGRT KTKTETVTKY LQEDLHIPAD KMNVVIFAGD DPGKNNKISW 

       190        200        210        220        230 
MKEHKLKLYY GDADADIAAA HELNIRGIRI LRASNSSYQP LPKAGRFGEE VVIKSEY 

« Hide

References

[1]"Complete genome sequence of Xenorhabdus nematophila (strain ATCC 19061 / DSM 3370 / LMG 1036 / NCIB 9965 / AN6)."
Goodrich-Blair H., Barbazuk B., Bode H.B., Darby C., Du Z., Forst S., Gaudriault S., Goldman B.S., Goodner B., Henkhaus J., Latreille P., Medigue C., Miller N., Norton S., Ogier J.C., Rouy Z., Slater S., Suen G.
Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SS-2004.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FN667741 Genomic DNA. Translation: CBJ79941.1.
RefSeqYP_003466735.1. NC_013892.1.

3D structure databases

ProteinModelPortalD3UWV6.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCBJ79941; CBJ79941; XBJ1_0800.
GeneID8830427.
KEGGxbo:XBJ1_0800.
PATRIC35296696. VBIXenBov95754_0721.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000270623.
KOK03788.

Enzyme and pathway databases

BioCycXBOV406818:GHLH-800-MONOMER.

Family and domain databases

Gene3D3.40.50.1000. 1 hit.
InterProIPR005519. Acid_phosphat_B.
IPR023214. HAD-like_dom.
IPR010025. HAD-SF_ppase_IIIB_AphA.
[Graphical view]
PfamPF03767. Acid_phosphat_B. 1 hit.
[Graphical view]
PIRSFPIRSF017818. Acid_Ptase_B. 1 hit.
SUPFAMSSF56784. SSF56784. 1 hit.
TIGRFAMsTIGR01672. AphA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAPHA_XENBS
AccessionPrimary (citable) accession number: D3UWV6
Entry history
Integrated into UniProtKB/Swiss-Prot: January 25, 2012
Last sequence update: April 20, 2010
Last modified: April 16, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families