Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

D3US10

- D3US10_LISSS

UniProt

D3US10 - D3US10_LISSS

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Thymidine kinase

Gene

tdk

Organism
Listeria seeligeri serovar 1/2b (strain ATCC 35967 / DSM 20751 / CIP 100100 / SLCC 3954)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei86 – 861Proton acceptorUniRule annotation
Metal bindingi143 – 1431ZincUniRule annotation
Metal bindingi146 – 1461ZincUniRule annotation
Metal bindingi181 – 1811ZincUniRule annotation
Metal bindingi184 – 1841ZincUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi9 – 168ATPUniRule annotation
Nucleotide bindingi85 – 884ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. thymidine kinase activity Source: UniProtKB-HAMAP
  3. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotation, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Metal-bindingUniRule annotationSAAS annotation, Nucleotide-binding, ZincUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciLSEE683837:GI10-2522-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotation
Ordered Locus Names:lse_2445Imported
OrganismiListeria seeligeri serovar 1/2b (strain ATCC 35967 / DSM 20751 / CIP 100100 / SLCC 3954)Imported
Taxonomic identifieri683837 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
ProteomesiUP000002044: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliD3US10.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000076391.
KOiK00857.
OMAiDEITAYI.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00124. Thymidine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3US10-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAQLFFRYGS MNSGKTIEIL KVAHNYEEQN KTVVIFTSGI DDRDQVGFIS
60 70 80 90 100
SRIGLKREAT PIFSDTNIYE IVADITPKPS CVLLDESQFL EKEHVFQLAK
110 120 130 140 150
IVDDLNIPVI AYGLKNDFRN ELFEGSKYLL LYADKLEEMK TICWFCAKKA
160 170 180 190
TMVLRVDDKG KPVYTGEQIM IGGNDHYYPV CRKCHAHPPI K
Length:191
Mass (Da):21,849
Last modified:April 20, 2010 - v1
Checksum:i72D565DD83D60586
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FN557490 Genomic DNA. Translation: CBH28596.1.
RefSeqiYP_003465678.1. NC_013891.1.

Genome annotation databases

EnsemblBacteriaiCBH28596; CBH28596; lse_2445.
GeneIDi9081327.
KEGGilsg:lse_2445.
PATRICi32264906. VBILisSee138575_2447.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FN557490 Genomic DNA. Translation: CBH28596.1 .
RefSeqi YP_003465678.1. NC_013891.1.

3D structure databases

ProteinModelPortali D3US10.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CBH28596 ; CBH28596 ; lse_2445 .
GeneIDi 9081327.
KEGGi lsg:lse_2445.
PATRICi 32264906. VBILisSee138575_2447.

Phylogenomic databases

HOGENOMi HOG000076391.
KOi K00857.
OMAi DEITAYI.

Enzyme and pathway databases

BioCyci LSEE683837:GI10-2522-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00124. Thymidine_kinase.
InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
PROSITEi PS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35967 / DSM 20751 / CIP 100100 / SLCC 3954Imported.

Entry informationi

Entry nameiD3US10_LISSS
AccessioniPrimary (citable) accession number: D3US10
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: October 29, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3