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Protein

Glutamate decarboxylase

Gene

gadB1

Organism
Listeria seeligeri serovar 1/2b (strain ATCC 35967 / DSM 20751 / CIP 100100 / SLCC 3954)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciLSEE683837:GI10-2327-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Name:gadB1Imported
Ordered Locus Names:lse_2270Imported
OrganismiListeria seeligeri serovar 1/2b (strain ATCC 35967 / DSM 20751 / CIP 100100 / SLCC 3954)Imported
Taxonomic identifieri683837 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
ProteomesiUP000002044: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000070228.
KOiK01580.
OMAiLHEMPER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

D3UR50-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLYSKENQES YLEPVFGSSA EDRDIPKYTL GKEPLEPRIA YRLVKDELLD
60 70 80 90 100
EGSARQNLAT FCQTYMEDEA TKLMSETLEK NAIDKSEYPR TAELENRCVN
110 120 130 140 150
IIADLWHAPK DQKFMGTSTI GSSEACMLGG MAMKFAWRKC AEKLGLDIYA
160 170 180 190 200
QKPNLVISSG YQVCWEKFCV YWDIDMRIVP MDKDHMQLNT DQVLDYIDEY
210 220 230 240 250
TIGVVGILGI TYTGRYDDIY ALNEKIEQYN SQTDYKVYIH VDAASGGFFT
260 270 280 290 300
PFVEPDIIWD FRLKNVISIN TSGHKYGLVY PGVGWVLWKD ESYLPKELIF
310 320 330 340 350
KVSYLGGEMP TMQINFSRSA SHIIGQYYNF LRYGFEGYRS IHQKTSDVAQ
360 370 380 390 400
YLANAVEETG YFDIYNDGSH LPIVCYKLKD NINVNWTLYD LADRLQMRGW
410 420 430 440 450
QVPAYPLPKN LENIVIQRYV CRADLGFNMA EEFIQDFKTS IEELNNAHIL
460
FHDTQKSGVH GFTH
Length:464
Mass (Da):53,553
Last modified:April 20, 2010 - v1
Checksum:iB9AC0DD4AEDB3622
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN557490 Genomic DNA. Translation: CBH28421.1.
RefSeqiYP_003465503.1. NC_013891.1.

Genome annotation databases

EnsemblBacteriaiCBH28421; CBH28421; lse_2270.
GeneIDi9081135.
KEGGilsg:lse_2270.
PATRICi32264506. VBILisSee138575_2267.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN557490 Genomic DNA. Translation: CBH28421.1.
RefSeqiYP_003465503.1. NC_013891.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCBH28421; CBH28421; lse_2270.
GeneIDi9081135.
KEGGilsg:lse_2270.
PATRICi32264506. VBILisSee138575_2267.

Phylogenomic databases

HOGENOMiHOG000070228.
KOiK01580.
OMAiLHEMPER.

Enzyme and pathway databases

BioCyciLSEE683837:GI10-2327-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35967 / DSM 20751 / CIP 100100 / SLCC 3954Imported.

Entry informationi

Entry nameiD3UR50_LISSS
AccessioniPrimary (citable) accession number: D3UR50
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: February 4, 2015
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.