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D3UQH9

- D3UQH9_LISSS

UniProt

D3UQH9 - D3UQH9_LISSS

Protein

Regulatory protein Spx

Gene

spxA

Organism
Listeria seeligeri serovar 1/2b (strain ATCC 35967 / DSM 20751 / CIP 100100 / SLCC 3954)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 28 (01 Oct 2014)
      Sequence version 1 (20 Apr 2010)
      Previous versions | rss
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    Functioni

    Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress.UniRule annotation

    GO - Biological processi

    1. negative regulation of transcription, DNA-templated Source: UniProtKB-HAMAP
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Biological processi

    Transcription, Transcription regulationUniRule annotation

    Enzyme and pathway databases

    BioCyciLSEE683837:GI10-2228-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Regulatory protein SpxUniRule annotation
    Gene namesi
    Name:spxAUniRule annotation
    Ordered Locus Names:lse_2171Imported
    OrganismiListeria seeligeri serovar 1/2b (strain ATCC 35967 / DSM 20751 / CIP 100100 / SLCC 3954)Imported
    Taxonomic identifieri683837 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
    ProteomesiUP000002044: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi10 ↔ 13Redox-activeUniRule annotation

    Keywords - PTMi

    Disulfide bondUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliD3UQH9.
    SMRiD3UQH9. Positions 1-118.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ArsC family. Spx subfamily.UniRule annotation

    Keywords - Domaini

    Redox-active centerUniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000059715.
    KOiK16509.
    OMAiRPIIMDD.

    Family and domain databases

    Gene3Di3.40.30.10. 1 hit.
    HAMAPiMF_01132. SpxA.
    InterProiIPR006660. Arsenate_reductase-like.
    IPR023731. Spx.
    IPR012336. Thioredoxin-like_fold.
    IPR006504. Tscrpt_reg_Spx/MgsR.
    [Graphical view]
    PfamiPF03960. ArsC. 1 hit.
    [Graphical view]
    SUPFAMiSSF52833. SSF52833. 1 hit.
    TIGRFAMsiTIGR01617. arsC_related. 1 hit.
    PROSITEiPS51353. ARSC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D3UQH9-1 [UniParc]FASTAAdd to Basket

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    MVTLYTSPSC TSCRKARAWL EEHDIPYKER NIFSEPLSLD EIKEILRMTE    50
    DGTDEIISTR SKTFQKLNVD LDSLPLQQLF ELIQKNPGLL RRPIIIDEKR 100
    LQVGYNEDEI RRFLPRRVRT YQLREAQKMV N 131
    Length:131
    Mass (Da):15,582
    Last modified:April 20, 2010 - v1
    Checksum:i67181E1BA6CD9444
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FN557490 Genomic DNA. Translation: CBH28322.1.
    RefSeqiYP_003465404.1. NC_013891.1.

    Genome annotation databases

    EnsemblBacteriaiCBH28322; CBH28322; lse_2171.
    GeneIDi9080888.
    KEGGilsg:lse_2171.
    PATRICi32264308. VBILisSee138575_2168.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FN557490 Genomic DNA. Translation: CBH28322.1 .
    RefSeqi YP_003465404.1. NC_013891.1.

    3D structure databases

    ProteinModelPortali D3UQH9.
    SMRi D3UQH9. Positions 1-118.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CBH28322 ; CBH28322 ; lse_2171 .
    GeneIDi 9080888.
    KEGGi lsg:lse_2171.
    PATRICi 32264308. VBILisSee138575_2168.

    Phylogenomic databases

    HOGENOMi HOG000059715.
    KOi K16509.
    OMAi RPIIMDD.

    Enzyme and pathway databases

    BioCyci LSEE683837:GI10-2228-MONOMER.

    Family and domain databases

    Gene3Di 3.40.30.10. 1 hit.
    HAMAPi MF_01132. SpxA.
    InterProi IPR006660. Arsenate_reductase-like.
    IPR023731. Spx.
    IPR012336. Thioredoxin-like_fold.
    IPR006504. Tscrpt_reg_Spx/MgsR.
    [Graphical view ]
    Pfami PF03960. ArsC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52833. SSF52833. 1 hit.
    TIGRFAMsi TIGR01617. arsC_related. 1 hit.
    PROSITEi PS51353. ARSC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 35967 / DSM 20751 / CIP 100100 / SLCC 3954Imported.

    Entry informationi

    Entry nameiD3UQH9_LISSS
    AccessioniPrimary (citable) accession number: D3UQH9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 20, 2010
    Last sequence update: April 20, 2010
    Last modified: October 1, 2014
    This is version 28 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3