D3UQH9 (D3UQH9_LISSS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Regulatory protein spx HAMAP-Rule MF_01132

Gene names

Name:	spxA HAMAP-Rule MF_01132
Ordered Locus Names:	lse_2171

Organism

Listeria seeligeri serovar 1/2b (strain ATCC 35967 / DSM 20751 / CIP 100100 / SLCC 3954) [Complete proteome] [HAMAP]

Taxonomic identifier

683837 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Listeriaceae › Listeria › Listeria seeligeri

Protein attributes

Sequence length	131 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress By similarity. HAMAP-Rule MF_01132
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_01132.
Sequence similarities	Belongs to the ArsC family. Spx subfamily. HAMAP-Rule MF_01132

Ontologies

Keywords
Biological process	Transcription Transcription regulation HAMAP-Rule MF_01132
Cellular component	Cytoplasm HAMAP-Rule MF_01132
Domain	Redox-active center HAMAP-Rule MF_01132
PTM	Disulfide bond HAMAP-Rule MF_01132
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	negative regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: HAMAP transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Amino acid modifications
	Disulfide bond	10 ↔ 13		Redox-active By similarity HAMAP-Rule MF_01132

Sequences

	Sequence		Length	Mass (Da)
	D3UQH9 [UniParc]. Last modified April 20, 2010. Version 1. Checksum: 67181E1BA6CD9444	FASTA	131	15,582
	10 20 30 40 50 60 MVTLYTSPSC TSCRKARAWL EEHDIPYKER NIFSEPLSLD EIKEILRMTE DGTDEIISTR 70 80 90 100 110 120 SKTFQKLNVD LDSLPLQQLF ELIQKNPGLL RRPIIIDEKR LQVGYNEDEI RRFLPRRVRT 130 YQLREAQKMV N

References

[1]

"Complete genome sequence of Listeria seeligeri, a nonpathogenic member of the genus Listeria." Steinweg C., Kuenne C.T., Billion A., Mraheil M.A., Domann E., Ghai R., Barbuddhe S.B., Karst U., Goesmann A., Puhler A., Weisshaar B., Wehland J., Lampidis R., Kreft J., Goebel W., Chakraborty T., Hain T. J. Bacteriol. 192:1473-1474(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35967 / DSM 20751 / CIP 100100 / SLCC 3954.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FN557490 Genomic DNA. Translation: CBH28322.1.
RefSeq	YP_003465404.1. NC_013891.1.
3D structure databases
ProteinModelPortal	D3UQH9.
SMR	D3UQH9. Positions 1-118.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CBH28322; CBH28322; lse_2171.
GeneID	9080888.
KEGG	lsg:lse_2171.
PATRIC	32264308. VBILisSee138575_2168.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000059715.
KO	K16509.
Enzyme and pathway databases
BioCyc	LSEE683837:GI10-1593-MONOMER.
Family and domain databases
Gene3D	3.40.30.10. 1 hit.
HAMAP	MF_01132. SpxA.
InterPro	IPR006660. Arsenate_reductase-like. IPR012336. Thioredoxin-like_fold. IPR023731. Tscrpt_reg_Spx. IPR006504. Tscrpt_reg_Spx/MgsR. [Graphical view]
Pfam	PF03960. ArsC. 1 hit. [Graphical view]
SUPFAM	SSF52833. Thiordxn-like_fd. 1 hit.
TIGRFAMs	TIGR01617. arsC_related. 1 hit.
PROSITE	PS51353. ARSC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D3UQH9_LISSS

Accession

Primary (citable) accession number: D3UQH9

Entry history

Integrated into UniProtKB/TrEMBL:	April 20, 2010
Last sequence update:	April 20, 2010
Last modified:	May 1, 2013
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)