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D3UQH9

- D3UQH9_LISSS

UniProt

D3UQH9 - D3UQH9_LISSS

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Protein
Regulatory protein Spx
Gene
spxA, lse_2171
Organism
Listeria seeligeri serovar 1/2b (strain ATCC 35967 / DSM 20751 / CIP 100100 / SLCC 3954)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress By similarity.UniRule annotation

GO - Biological processi

  1. negative regulation of transcription, DNA-templated Source: UniProtKB-HAMAP
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotation

Enzyme and pathway databases

BioCyciLSEE683837:GI10-2228-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Regulatory protein SpxUniRule annotation
Gene namesi
Name:spxAUniRule annotation
Ordered Locus Names:lse_2171Imported
OrganismiListeria seeligeri serovar 1/2b (strain ATCC 35967 / DSM 20751 / CIP 100100 / SLCC 3954)Imported
Taxonomic identifieri683837 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
ProteomesiUP000002044: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi10 ↔ 13Redox-active By similarityUniRule annotation

Keywords - PTMi

Disulfide bondUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliD3UQH9.
SMRiD3UQH9. Positions 1-118.

Family & Domainsi

Sequence similaritiesi

Belongs to the ArsC family. Spx subfamily.UniRule annotation

Keywords - Domaini

Redox-active centerUniRule annotation

Phylogenomic databases

HOGENOMiHOG000059715.
KOiK16509.
OMAiRPIIMDD.

Family and domain databases

Gene3Di3.40.30.10. 1 hit.
HAMAPiMF_01132. SpxA.
InterProiIPR006660. Arsenate_reductase-like.
IPR023731. Spx.
IPR012336. Thioredoxin-like_fold.
IPR006504. Tscrpt_reg_Spx/MgsR.
[Graphical view]
PfamiPF03960. ArsC. 1 hit.
[Graphical view]
SUPFAMiSSF52833. SSF52833. 1 hit.
TIGRFAMsiTIGR01617. arsC_related. 1 hit.
PROSITEiPS51353. ARSC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3UQH9-1 [UniParc]FASTAAdd to Basket

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MVTLYTSPSC TSCRKARAWL EEHDIPYKER NIFSEPLSLD EIKEILRMTE    50
DGTDEIISTR SKTFQKLNVD LDSLPLQQLF ELIQKNPGLL RRPIIIDEKR 100
LQVGYNEDEI RRFLPRRVRT YQLREAQKMV N 131
Length:131
Mass (Da):15,582
Last modified:April 20, 2010 - v1
Checksum:i67181E1BA6CD9444
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FN557490 Genomic DNA. Translation: CBH28322.1.
RefSeqiYP_003465404.1. NC_013891.1.

Genome annotation databases

EnsemblBacteriaiCBH28322; CBH28322; lse_2171.
GeneIDi9080888.
KEGGilsg:lse_2171.
PATRICi32264308. VBILisSee138575_2168.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FN557490 Genomic DNA. Translation: CBH28322.1 .
RefSeqi YP_003465404.1. NC_013891.1.

3D structure databases

ProteinModelPortali D3UQH9.
SMRi D3UQH9. Positions 1-118.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CBH28322 ; CBH28322 ; lse_2171 .
GeneIDi 9080888.
KEGGi lsg:lse_2171.
PATRICi 32264308. VBILisSee138575_2168.

Phylogenomic databases

HOGENOMi HOG000059715.
KOi K16509.
OMAi RPIIMDD.

Enzyme and pathway databases

BioCyci LSEE683837:GI10-2228-MONOMER.

Family and domain databases

Gene3Di 3.40.30.10. 1 hit.
HAMAPi MF_01132. SpxA.
InterProi IPR006660. Arsenate_reductase-like.
IPR023731. Spx.
IPR012336. Thioredoxin-like_fold.
IPR006504. Tscrpt_reg_Spx/MgsR.
[Graphical view ]
Pfami PF03960. ArsC. 1 hit.
[Graphical view ]
SUPFAMi SSF52833. SSF52833. 1 hit.
TIGRFAMsi TIGR01617. arsC_related. 1 hit.
PROSITEi PS51353. ARSC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35967 / DSM 20751 / CIP 100100 / SLCC 3954.

Entry informationi

Entry nameiD3UQH9_LISSS
AccessioniPrimary (citable) accession number: D3UQH9
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: September 3, 2014
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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