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D3UML3 (D3UML3_LISSS) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO HAMAP-Rule MF_01037

EC=2.1.1.74 HAMAP-Rule MF_01037
Alternative name(s):
Folate-dependent tRNA (uracil-5-)-methyltransferase HAMAP-Rule MF_01037
Folate-dependent tRNA(M-5-U54)-methyltransferase HAMAP-Rule MF_01037
Gene names
Name:gid EMBL CBH27346.1
Synonyms:trmFO HAMAP-Rule MF_01037
Ordered Locus Names:lse_1195 EMBL CBH27346.1
OrganismListeria seeligeri serovar 1/2b (strain ATCC 35967 / DSM 20751 / CIP 100100 / SLCC 3954) [Complete proteome] [HAMAP] EMBL CBH27346.1
Taxonomic identifier683837 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria

Protein attributes

Sequence length434 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs By similarity. HAMAP-Rule MF_01037 SAAS SAAS004417

Catalytic activity

5,10-methylenetetrahydrofolate + uracil54 in tRNA + FADH2 = tetrahydrofolate + 5-methyluracil54 in tRNA + FAD. HAMAP-Rule MF_01037 SAAS SAAS004417

Cofactor

FAD By similarity. HAMAP-Rule MF_01037 SAAS SAAS004417

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01037.

Sequence similarities

Belongs to the MnmG family. TrmFO subfamily. HAMAP-Rule MF_01037

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding9 – 146FAD By similarity HAMAP-Rule MF_01037

Sequences

Sequence LengthMass (Da)Tools
D3UML3 [UniParc].

Last modified April 20, 2010. Version 1.
Checksum: A9670A30ACBB0FB6

FASTA43447,849
        10         20         30         40         50         60 
MEKRVNVIGA GLAGSEATWQ LVKRGIEVDL YEMRPVKQTP AHHTDKFAEL VCTNSLRANG 

        70         80         90        100        110        120 
LTNAVGVIKE EMRILDSIII EAADEASVPA GGALAVDRHE FSGYITDKVK NHPLVTVHTE 

       130        140        150        160        170        180 
EVTTIPTGPT IIATGPLTSP ALAEEIKRLT GEEYLYFYDA AAPIIEKESI DMNKVYLKSR 

       190        200        210        220        230        240 
YDKGEAAYLN CPMSEEEFKA FYEALVTAET AALKDFEKEV FFEGCMPIEV MAKRGIKTML 

       250        260        270        280        290        300 
FGPLKPVGLE DPKNGKRPYA VLQLRQDDAA GSLYNMVGFQ THLKWGEQKR VFGMIPGLEN 

       310        320        330        340        350        360 
AEIVRYGVMH RNTFINSPTV LEPTYQLKSR NDLFFAGQMT GVEGYVESAA SGLAAGINAA 

       370        380        390        400        410        420 
NFVEEKELII FPKETAIGSL AHYITSASKK SFQPMNVNFG LFPELASKIR VKQERNEKLA 

       430 
ERALNAIKGV AEGL 

« Hide

References

[1]"Complete genome sequence of Listeria seeligeri, a nonpathogenic member of the genus Listeria."
Steinweg C., Kuenne C.T., Billion A., Mraheil M.A., Domann E., Ghai R., Barbuddhe S.B., Karst U., Goesmann A., Puhler A., Weisshaar B., Wehland J., Lampidis R., Kreft J., Goebel W., Chakraborty T., Hain T.
J. Bacteriol. 192:1473-1474(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 35967 / DSM 20751 / CIP 100100 / SLCC 3954.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FN557490 Genomic DNA. Translation: CBH27346.1.
RefSeqYP_003464432.1. NC_013891.1.

3D structure databases

ProteinModelPortalD3UML3.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCBH27346; CBH27346; lse_1195.
GeneID9082759.
KEGGlsg:lse_1195.
PATRIC32262285. VBILisSee138575_1189.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000252054.
KOK04094.
OMAEIYFEGC.

Enzyme and pathway databases

BioCycLSEE683837:GI10-1218-MONOMER.

Family and domain databases

HAMAPMF_01037. TrmFO.
InterProIPR004417. Folate-dep_Ribothymidyl_synth.
IPR002218. GIDA-rel.
IPR020595. GIDA-rel_CS.
[Graphical view]
PfamPF01134. GIDA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00137. gid_trmFO. 1 hit.
PROSITEPS01281. GIDA_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD3UML3_LISSS
AccessionPrimary (citable) accession number: D3UML3
Entry history
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: June 11, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)