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D3ULC3 (D3ULC3_LISSS) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047
EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddlA EMBL CBH26906.1
Synonyms:ddl HAMAP-Rule MF_00047
Ordered Locus Names:lse_0755
OrganismListeria seeligeri serovar 1/2b (strain ATCC 35967 / DSM 20751 / CIP 100100 / SLCC 3954) [Complete proteome] [HAMAP]
Taxonomic identifier683837 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Bacillales › Listeriaceae › Listeria ›

Protein attributes

Sequence length370 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS005905

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS005905

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS005905.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047 SAAS SAAS005905

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain144 – 352209ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding177 – 23256ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding3061Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3191Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3191Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding3211Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
D3ULC3 [UniParc].

Last modified April 20, 2010. Version 1.
Checksum: 2084270F33552334

FASTA37040,789
        10         20         30         40         50         60 
MKTKLILLYG GKSAEHEVSL QTAFSVINAL NLDKFEAQPI YITNEGEWVQ GPLLSGKLDF 

        70         80         90        100        110        120 
VEQLRFAATD KIELALTETE KSSGELISPA VLEADGQETV VFPLLHGPNG EDGTVQGLFE 

       130        140        150        160        170        180 
VLNIPYVGNG VLASSAAMDK IVMKKIFADA AIPQVPAVAV RLIDWKNFKD EMIAEMEEVL 

       190        200        210        220        230        240 
EYPVFVKPAN LGSSVGISKA TNKQELTEAM TEAFLYDRRV VVEQGVVARE IEMGVLGNDT 

       250        260        270        280        290        300 
PICSVPGEIL PEGAVAKFYD YKAKYQDNNT TLIIPTEVEP EVLAQMKDYA IQAFLGLDAS 

       310        320        330        340        350        360 
GLVRADFFLT DDNQLFLNEV NTMPGFTPYS MYPLLWQESG LPYPALIERL VDLAKERHAA 

       370 
KNALKYKLED

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References

[1]"Complete genome sequence of Listeria seeligeri, a nonpathogenic member of the genus Listeria."
Steinweg C., Kuenne C.T., Billion A., Mraheil M.A., Domann E., Ghai R., Barbuddhe S.B., Karst U., Goesmann A., Puhler A., Weisshaar B., Wehland J., Lampidis R., Kreft J., Goebel W., Chakraborty T., Hain T.
J. Bacteriol. 192:1473-1474(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 35967 / DSM 20751 / CIP 100100 / SLCC 3954.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		FN557490 Genomic DNA. Translation: CBH26906.1.
RefSeqYP_003463994.1. NC_013891.1.

3D structure databases

ProteinModelPortalD3ULC3.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCBH26906; CBH26906; lse_0755.
GeneID9082737.
KEGGlsg:lse_0755.
PATRIC32261407. VBILisSee138575_0756.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000011593.
KOK01921.

Enzyme and pathway databases

BioCycLSEE683837:GI10-2123-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. PreATP-grasp-like. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD3ULC3_LISSS
AccessionPrimary (citable) accession number: D3ULC3
Entry history
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: May 1, 2013
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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