D3UGP7 (D3UGP7_HELM1) Unreviewed, UniProtKB/TrEMBL
Last modified
May 1, 2013.
Version 25.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Submitted name: Isocitrate dehydrogenase EMBL CBG39668.1 EC=1.1.1.42 EMBL CBG39668.1 | ||||
| Gene names |
| ||||
| Organism | Helicobacter mustelae (strain ATCC 43772 / LMG 18044 / NCTC 12198 / 12198) (Campylobacter mustelae) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 679897 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Helicobacter › ![]() |
Protein attributes
| Sequence length | 742 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Cofactor | Binds 1 magnesium or manganese ion per subunit By similarity. PIRSR PIRSR009407-3 |
Ontologies
| Keywords | |
|---|---|
| Ligand | Magnesium PIRSR PIRSR009407-3 Metal-binding PIRSR PIRSR009407-3 |
| Molecular function | Oxidoreductase EMBL CBG39668.1 |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological_process | tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro |
| Molecular_function | isocitrate dehydrogenase (NADP+) activity Inferred from electronic annotation. Source: EC metal ion bindingInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Regions | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Region | 129 – 136 | 8 | Substrate binding By similarity PIRSR PIRSR009407-2 | ||||||
Sites | |||||||||
| Metal binding | 345 | 1 | Magnesium or manganese By similarity PIRSR PIRSR009407-3 | ||||||
| Metal binding | 548 | 1 | Magnesium or manganese By similarity PIRSR PIRSR009407-3 | ||||||
| Metal binding | 552 | 1 | Magnesium or manganese By similarity PIRSR PIRSR009407-3 | ||||||
| Binding site | 142 | 1 | Substrate By similarity PIRSR PIRSR009407-2 | ||||||
| Binding site | 547 | 1 | Substrate By similarity PIRSR PIRSR009407-2 | ||||||
| Site | 252 | 1 | Critical for catalysis By similarity PIRSR PIRSR009407-1 | ||||||
| Site | 415 | 1 | Critical for catalysis By similarity PIRSR PIRSR009407-1 | ||||||
Sequences
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References
| [1] | "Comparative genomics and proteomics of Helicobacter mustelae, an ulcerogenic and carcinogenic gastric pathogen." O'Toole P.W., Snelling W.J., Canchaya C., Forde B.M., Hardie K.R., Josenhans C., Graham R.L.J., McMullan G., Parkhill J., Belda E., Bentley S.D. BMC Genomics 11:164-164(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43772 / LMG 18044 / NCTC 12198 / 12198. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | FN555004 Genomic DNA. Translation: CBG39668.1. |
| RefSeq | YP_003516410.1. NC_013949.1. |
3D structure databases | |
| ProteinModelPortal | D3UGP7. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | CBG39668; CBG39668; HMU04060. |
| GeneID | 8866251. |
| KEGG | hms:HMU04060. |
| PATRIC | 35378142. VBIHelMus149082_0479. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | HOG000240860. |
| KO | K00031. |
| OMA | PRTMGTV. |
Enzyme and pathway databases | |
| BioCyc | HMUS679897:GJBK-426-MONOMER. |
Family and domain databases | |
| Gene3D | 3.40.718.10. 3 hits. |
| InterPro | IPR004436. Isocitrate_DH_NADP_mono. IPR024084. IsoPropMal-DH-like_dom. [Graphical view] |
| Pfam | PF03971. IDH. 1 hit. [Graphical view] |
| PIRSF | PIRSF009407. IDH_monmr. 1 hit. |
| TIGRFAMs | TIGR00178. monomer_idh. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | D3UGP7_HELM1 | ||||||||
| Accession | Primary (citable) accession number: D3UGP7 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

Clusters with
