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D3TTZ5 (D3TTZ5_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 14. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
Name:TNFAIP3 EMBL ACN87241.1
OrganismHomo sapiens (Human) EMBL ACN87241.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length167 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 OTU domain. SAAS SAAS003323

Ontologies

Gene Ontology (GO)
   Biological_processB-1 B cell homeostasis

Inferred from electronic annotation. Source: Compara

negative regulation of B cell activation

Inferred from electronic annotation. Source: Compara

negative regulation of cell death

Inferred from electronic annotation. Source: Compara

negative regulation of chronic inflammatory response

Inferred from electronic annotation. Source: Compara

negative regulation of cyclin-dependent protein serine/threonine kinase activity

Inferred from electronic annotation. Source: Compara

negative regulation of interleukin-1 beta production

Inferred from electronic annotation. Source: Compara

negative regulation of interleukin-6 production

Inferred from electronic annotation. Source: Compara

negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway

Inferred from electronic annotation. Source: Compara

negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

Inferred from electronic annotation. Source: Compara

negative regulation of toll-like receptor 5 signaling pathway

Inferred from electronic annotation. Source: Compara

negative regulation of tumor necrosis factor production

Inferred from electronic annotation. Source: Compara

positive regulation of hepatocyte proliferation

Inferred from electronic annotation. Source: Compara

protein deubiquitination

Inferred from electronic annotation. Source: Compara

regulation of germinal center formation

Inferred from electronic annotation. Source: Compara

response to molecule of bacterial origin

Inferred from electronic annotation. Source: Compara

response to muramyl dipeptide

Inferred from electronic annotation. Source: Compara

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: Compara

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
D3TTZ5 [UniParc].

Last modified April 20, 2010. Version 1.
Checksum: C5966E36F5FC7CAE

FASTA16719,907
        10         20         30         40         50         60 
MAEQVLPQAL YLSNMRKAVK IRERTPEDIF KPTNGIIHHF KTMHRYTLEM FRTCQFCPQF 

        70         80         90        100        110        120 
REIIHKALID RNIQATLESQ KKLNWCREVR KLVALKTNGD GNCLMHATSQ YMWGVQDTDL 

       130        140        150        160 
VLRKALFSTL KETDTRNFKF RWQLESLKSQ EFVETGLCYD TRNWNDE 

« Hide

References

[1]"Inactivation of a negative regulator of inflammation in malignant lymphomas of B cell lineage."
Kato M., Kobayashi Y., Ogawa S.
Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Mt15 EMBL ACN87241.1.
Tissue: Primary lymphoma EMBL ACN87241.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FJ434415 mRNA. Translation: ACN87241.1.
IPIIPI01011060.
UniGeneHs.211600.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Gene expression databases

ArrayExpressD3TTZ5.
BgeeD3TTZ5.

Family and domain databases

InterProIPR003323. OTU.
[Graphical view]
PfamPF02338. OTU. 1 hit.
[Graphical view]
PROSITEPS50802. OTU. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSTNFAIP3. human.
NextBio35490454.

Entry information

Entry nameD3TTZ5_HUMAN
AccessionPrimary (citable) accession number: D3TTZ5
Entry history
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: May 1, 2013
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.