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Protein
Submitted name:

Retinoic acid inducible protein I

Gene

RIG-I

Organism
Anas platyrhynchos (Mallard) (Anas boschas)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei706ADPCombined sources1
Binding sitei733ADPCombined sources1
Metal bindingi812ZincCombined sources1
Metal bindingi815ZincCombined sources1
Metal bindingi866ZincCombined sources1
Metal bindingi871ZincCombined sources1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi245 – 250ADPCombined sources6
Nucleotide bindingi270 – 274ADPCombined sources5

GO - Molecular functioni

Keywordsi

LigandMetal-bindingCombined sources, Nucleotide-bindingCombined sources, ZincCombined sources

Names & Taxonomyi

Protein namesi
Submitted name:
Retinoic acid inducible protein IImported
Submitted name:
Retinoic acid inducible protein I transcript variant 1Imported
Submitted name:
Retinoic acid inducible protein I transcript variant 2Imported
Gene namesi
Name:RIG-IImported
OrganismiAnas platyrhynchos (Mallard) (Anas boschas)Imported
Taxonomic identifieri8839 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeAnseriformesAnatidaeAnatinaeAnas

Subcellular locationi

PTM / Processingi

PTM databases

iPTMnetiD3TI84

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4A2PX-ray3.00A242-794[»]
4A2QX-ray3.40A/B/D/E1-794[»]
4A2VX-ray1.44A806-933[»]
4A2WX-ray3.70A/B2-933[»]
4A2XX-ray4.00A/B/C/D804-933[»]
4A36X-ray3.70A/B242-794[»]
SMRiD3TI84
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini254 – 432Helicase ATP-bindingInterPro annotationAdd BLAST179
Domaini611 – 792Helicase C-terminalInterPro annotationAdd BLAST182
Domaini794 – 928RLR CTRInterPro annotationAdd BLAST135

Phylogenomic databases

KOiK12646

Family and domain databases

CDDicd00079 HELICc, 1 hit
Gene3Di2.170.150.30, 1 hit
InterProiView protein in InterPro
IPR031964 CARD_dom
IPR011545 DEAD/DEAH_box_helicase_dom
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR038557 RLR_C_sf
IPR021673 RLR_CTR
PfamiView protein in Pfam
PF16739 CARD_2, 2 hits
PF00270 DEAD, 1 hit
PF00271 Helicase_C, 1 hit
PF11648 RIG-I_C-RD, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 3 hits
PROSITEiView protein in PROSITE
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
PS51789 RLR_CTR, 1 hit

Sequencei

Sequence statusi: Complete.

D3TI84-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTADEKRSLQ CYRRYIERSL NPVYVLGNMT DWLPDELRER IRKEEERGVS
60 70 80 90 100
GAAALFLDAV LQLEARGWFR GMLDAMLAAG YTGLAEAIEN WDFSKLEKLE
110 120 130 140 150
LHRQLLKRIE ATMLEVDPVA LIPYISTCLI DRECEEIQQI SENRSKAAGI
160 170 180 190 200
TKLIECLCRS DKEHWPKSLQ LALDTTGYYR ASELWDIRED NAKDVDSEMT
210 220 230 240 250
DASEDCLEAS MTYSEEAEPD DNLSENLGSA AEGIGKPPPV YETKKARSYQ
260 270 280 290 300
IELAQPAING KNALICAPTG SGKTFVSILI CEHHFQNMPA GRKAKVVFLA
310 320 330 340 350
TKVPVYEQQK NVFKHHFERQ GYSVQGISGE NFSNVSVEKV IEDSDIIVVT
360 370 380 390 400
PQILVNSFED GTLTSLSIFT LMIFDECHNT TGNHPYNVLM TRYLEQKFNS
410 420 430 440 450
ASQLPQILGL TASVGVGNAK NIEETIEHIC SLCSYLDIQA ISTVRENIQE
460 470 480 490 500
LQRFMNKPEI DVRLVKRRIH NPFAAIISNL MSETEALMRT IYSVDTLSQN
510 520 530 540 550
SKKDFGTQNY EHWIVVTQRK CRLLQLEDKE EESRICRALF ICTEHLRKYN
560 570 580 590 600
DALIISEDAR IIDALSYLTE FFTNVKNGPY TELEQHLTAK FQEKEPELIA
610 620 630 640 650
LSKDETNENP KLEELVCILD DAYRYNPQTR TLLFAKTRAL VSALKKCMEE
660 670 680 690 700
NPILNYIKPG VLMGRGRRDQ TTGMTLPSQK GVLDAFKTSK DNRLLIATSV
710 720 730 740 750
ADEGIDIVQC NLVVLYEYSG NVTKMIQVRG RGRAAGSKCI LVTSKTEVVE
760 770 780 790 800
NEKCNRYKEE MMNKAVEKIQ KWDEETFAKK IHNLQMKERV LRDSRRKEIK
810 820 830 840 850
PKVVEGQKNL LCGKCKAYAC STDDIRIIKD SHHIVLGEAF KERYTTKPHK
860 870 880 890 900
KPMQFDGFEK KSKMYCRNNN CQHDWGITVK YLTFDNLPVI KIKSFVMEST
910 920 930
ATGTQMDFQK WKSINSSLKN FDVEEMSNLY PPF
Length:933
Mass (Da):106,605
Last modified:April 20, 2010 - v1
Checksum:i642BE7324C693EA0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU363349 mRNA Translation: ACA61272.1
JQ946323 mRNA Translation: AFK82315.1
KC869660 mRNA Translation: AGS16703.1
RefSeqiNP_001297309.1, NM_001310380.1

Genome annotation databases

GeneIDi101789567
KEGGiapla:101789567

Similar proteinsi

Entry informationi

Entry nameiD3TI84_ANAPL
AccessioniPrimary (citable) accession number: D3TI84
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: March 28, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

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