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Protein
Submitted name:

D-alanine--D-alanine ligase

Gene

Thit_0058

Organism
Thermoanaerobacter italicus (strain DSM 9252 / Ab9)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. D-alanine-D-alanine ligase activity Source: UniProtKB-EC
  3. metal ion binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LigaseImported

Enzyme and pathway databases

BioCyciTITA580331:GHTM-69-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
D-alanine--D-alanine ligaseImported (EC:6.3.2.4Imported)
Gene namesi
Ordered Locus Names:Thit_0058Imported
OrganismiThermoanaerobacter italicus (strain DSM 9252 / Ab9)Imported
Taxonomic identifieri580331 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacteraceaeThermoanaerobacter
ProteomesiUP000001552: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliD3T586.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000037520.
KOiK01921.
OMAiPILEIDF.

Family and domain databases

Gene3Di3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
InterProiIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
[Graphical view]
PANTHERiPTHR23132. PTHR23132. 1 hit.
PfamiPF07478. Dala_Dala_lig_C. 1 hit.
[Graphical view]
PROSITEiPS50975. ATP_GRASP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3T586-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIGVLWRKF RNVEFQRKLM PDKVYDDAYD EAYHHYMAIK EAGFDSVLIE
60 70 80 90 100
WKEDPLETYE TIKKEKVDLI FNASSMKEVA FLEVFNIPYV GSGLDLVATD
110 120 130 140 150
KRMRKDIVAF HGLPTPKYVV AKNSQEIPPV GHLRFPLFVK PISGRGSAGI
160 170 180 190 200
DEENIVYDKD KLPQVVSKIT EKIGQAALIE EFIEGKEVTV GIIGYKHPQV
210 220 230 240 250
LPLLEVGYNN VKTNTYEHKM FDNEIIKCPM EVSKEVEEKI KETALNIYKV
260 270 280 290 300
LNAKDFARID MILSKDNVPY FLELNTFAGL TMSSSKGEKH VHHGYMGYMA
310 320
KAAGLTRGEF IGKIIESAIE RYKLK
Length:325
Mass (Da):37,108
Last modified:April 20, 2010 - v1
Checksum:iEFD98A4F05561916
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001936 Genomic DNA. Translation: ADD01387.1.
RefSeqiYP_003475949.1. NC_013921.1.

Genome annotation databases

EnsemblBacteriaiADD01387; ADD01387; Thit_0058.
GeneIDi8820363.
KEGGitit:Thit_0058.
PATRICi32495045. VBITheIta22270_0060.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001936 Genomic DNA. Translation: ADD01387.1.
RefSeqiYP_003475949.1. NC_013921.1.

3D structure databases

ProteinModelPortaliD3T586.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADD01387; ADD01387; Thit_0058.
GeneIDi8820363.
KEGGitit:Thit_0058.
PATRICi32495045. VBITheIta22270_0060.

Phylogenomic databases

HOGENOMiHOG000037520.
KOiK01921.
OMAiPILEIDF.

Enzyme and pathway databases

BioCyciTITA580331:GHTM-69-MONOMER.

Family and domain databases

Gene3Di3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
InterProiIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
[Graphical view]
PANTHERiPTHR23132. PTHR23132. 1 hit.
PfamiPF07478. Dala_Dala_lig_C. 1 hit.
[Graphical view]
PROSITEiPS50975. ATP_GRASP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Thermoanaerobacter italicus Ab9."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Mikhailova N., Hemme C.L., Woyke T.
    Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 9252 / Ab9Imported.

Entry informationi

Entry nameiD3T586_THEIA
AccessioniPrimary (citable) accession number: D3T586
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: January 7, 2015
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.