Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

D3SBL6

- D3SBL6_THISK

UniProt

D3SBL6 - D3SBL6_THISK

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Alanine racemase

Gene

TK90_1930

Organism
Thioalkalivibrio sp. (strain K90mix)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

Note: Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei35 – 351Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei130 – 1301SubstrateUniRule annotation
Active sitei265 – 2651Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei313 – 3131Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciTSP396595:GH8D-1975-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:TK90_1930Imported
OrganismiThioalkalivibrio sp. (strain K90mix)Imported
Taxonomic identifieri396595 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaChromatialesEctothiorhodospiraceaeThioalkalivibrio
ProteomesiUP000009099: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei35 – 351N6-(pyridoxal phosphate)lysineUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliD3SBL6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000031446.
KOiK01775.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3SBL6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRRAASIQLH PEALRHNLSV ARRLAPAVPM WSVIKAEGYG HGLLWAAQAL
60 70 80 90 100
ADDSDGLAVS QVCEARALRA AGFEGALLVL QGPRDLSEVH ACTEFDLQPV
110 120 130 140 150
LHHSAQLDHL EAASVVLPVV WIKLNTGMNR LGFEPAQAPK VATRLQAAGH
160 170 180 190 200
GQGGLHWMTH MACADEPEHP QNARQLDAFA TTVAAFPGHR SVANSAALFA
210 220 230 240 250
GWGRGGAAAG EYWGRPGIML YGAHPASVPA EHLPEGPDGD LRPAMTVQAP
260 270 280 290 300
IIATQPLAPG STVGYGATWT ADAPGRVGIV AMGYADGYPR HAPSGTPVLV
310 320 330 340 350
NGELCPLIGR VSMDMLAVDL SGVPAAQVGD RVTLWGEGLP VERVARAAGT
360
ISYELLTRVA DRLQPGN
Length:367
Mass (Da):38,517
Last modified:April 20, 2010 - v1
Checksum:i30B852CBF442D3A3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001905 Genomic DNA. Translation: ADC72421.1.
RefSeqiWP_012983296.1. NC_013889.1.
YP_003461157.1. NC_013889.1.

Genome annotation databases

EnsemblBacteriaiADC72421; ADC72421; TK90_1930.
GeneIDi8807703.
KEGGitkm:TK90_1930.
PATRICi32527432. VBIThiSp13812_1914.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001905 Genomic DNA. Translation: ADC72421.1 .
RefSeqi WP_012983296.1. NC_013889.1.
YP_003461157.1. NC_013889.1.

3D structure databases

ProteinModelPortali D3SBL6.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADC72421 ; ADC72421 ; TK90_1930 .
GeneIDi 8807703.
KEGGi tkm:TK90_1930.
PATRICi 32527432. VBIThiSp13812_1914.

Phylogenomic databases

HOGENOMi HOG000031446.
KOi K01775.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci TSP396595:GH8D-1975-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome of Thioalkalivibrio sp. K90mix."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Foster B., Sun H., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Sorokin D.Y., Muyzer G., Woyke T.
    Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K90mixImported.

Entry informationi

Entry nameiD3SBL6_THISK
AccessioniPrimary (citable) accession number: D3SBL6
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: November 26, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3