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D3S9R8 (D3S9R8_THISK) Unreviewed, UniProtKB/TrEMBL

Last modified October 16, 2013. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446

EC=1.1.1.42 RuleBase RU004446
Gene names
Ordered Locus Names:TK90_1264 EMBL ADC71773.1
OrganismThioalkalivibrio sp. (strain K90mix) [Complete proteome] [HAMAP] EMBL ADC71773.1
Taxonomic identifier396595 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaChromatialesEctothiorhodospiraceaeThioalkalivibrio

Protein attributes

Sequence length418 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity.

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
D3S9R8 [UniParc].

Last modified April 20, 2010. Version 1.
Checksum: E90E2DFD48FAE0C6

FASTA41845,727
        10         20         30         40         50         60 
MAYQHIQVPE KGERITVDEQ GKLVVPDRPI IPFIEGDGIG VDITPVMRRV TDAAVEKAYG 

        70         80         90        100        110        120 
GQKAIEWMEV YAGEKATQVY DDNSGLPEET LEAVKDYRVS IKGPLTTPVG GGFRSLNVAL 

       130        140        150        160        170        180 
RQKLDLFVCL RPVRYYDGTP SPLKEPEKTD MVIFRENSED IYAGIEFESG TPEVKKVIDF 

       190        200        210        220        230        240 
LQNEMGVTQI RFPDTAGIGV KPVSSEGTKR LVRKAIEYAI DNDRPSVTLV HKGNIMKFTE 

       250        260        270        280        290        300 
GSFKAWGYEL AREEFGAKDL DGGPWQTFKN PKTGREIVIK DVIADAFLQQ ILLRPEDYSV 

       310        320        330        340        350        360 
IATLNLNGDY ISDALAAQVG GIGIAPGANL SDTTAMFEAT HGTAPKYAGQ DKVNPGSLIL 

       370        380        390        400        410 
SAEMMLRHLG WSEAADRVVK GMGGAISAGE VTYDFARLMD NVEPVSCSAF GEALIKHM 

« Hide

References

[1]"Complete sequence of chromosome of Thioalkalivibrio sp. K90mix."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Foster B., Sun H., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Sorokin D.Y., Muyzer G., Woyke T.
Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K90mix.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001905 Genomic DNA. Translation: ADC71773.1.
RefSeqYP_003460509.1. NC_013889.1.

3D structure databases

ProteinModelPortalD3S9R8.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADC71773; ADC71773; TK90_1264.
GeneID8807028.
KEGGtkm:TK90_1264.
PATRIC32526092. VBIThiSp13812_1252.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000021113.
KOK00031.

Enzyme and pathway databases

BioCycTSP396595:GH8D-1299-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD3S9R8_THISK
AccessionPrimary (citable) accession number: D3S9R8
Entry history
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: October 16, 2013
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)