D3S6J6 (D3S6J6_METSF) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Probable 3-phosphoshikimate 1-carboxyvinyltransferase HAMAP-Rule MF_00210
EC=2.5.1.19 HAMAP-Rule MF_00210

Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase HAMAP-Rule MF_00210

Gene names

Name:	aroA HAMAP-Rule MF_00210
Ordered Locus Names:	MFS40622_1790

Organism

Methanocaldococcus sp. (strain FS406-22) [Complete proteome] [HAMAP]

Taxonomic identifier

644281 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus

Protein attributes

Sequence length	427 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP-Rule MF_00210
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP-Rule MF_00210 RuleBase RU004116
Subunit structure	Monomer By similarity. HAMAP-Rule MF_00210
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00210.
Sequence similarities	Belongs to the EPSP synthase family. HAMAP-Rule MF_00210 RuleBase RU004164

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis HAMAP-Rule MF_00210
Cellular component	Cytoplasm HAMAP-Rule MF_00210
Molecular function	Transferase HAMAP-Rule MF_00210 EMBL ADC70460.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP chorismate biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	3-phosphoshikimate 1-carboxyvinyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D3S6J6 [UniParc]. Last modified April 20, 2010. Version 1. Checksum: 2B1B2B90C3A88AF6	FASTA	427	46,557
	10 20 30 40 50 60 MLIVKKTDRL EGIVKAPPSK SYTHRAVIGA SLAEGISRII NPLWGADCLS SVHGCKMLGA 70 80 90 100 110 120 DITLDKEKDE WVVKGGELKT PDNIIDIGNS GTTLRILTSI ASQIPKGYAI LTGDESIRKR 130 140 150 160 170 180 PMQPLLDALK QLNIEAFSSK LDGTAPIIVK SGKIDGNVVK IRGDISSQFI TSLMMLLPFN 190 200 210 220 230 240 KEDTEIILTS PLKSKPYIDI TLDILNNFGI KIDKTDNGFL VYGNQKYKPI DYIVEGDYSS 250 260 270 280 290 300 ASYLIAAGVL INSNITIENL FANSKQGDKA IINIVKEMGA DVKVKKDRVI IEGEYSLEGI 310 320 330 340 350 360 DVDVKDIPDL VPTIAVLGCF AEGKTEIYNG EHVRLKECDR LRACAVELKK MGADIEEKPD 370 380 390 400 410 420 GLIIRGVKKL KGAKLNTYHD HRLVMAFTIA GLKAEGETII EGEEAVKISF PNFVDVMKSL GANIVVG

References

[1]

"Complete sequence of chromosome of Methanocaldococcus sp. FS406-22." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Teshima H., Detter J.C., Han C., Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Sieprawska-Lupa M., Leigh J., Whitman W.B., Woyke T. Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: FS406-22.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001901 Genomic DNA. Translation: ADC70460.1.
RefSeq	YP_003459196.1. NC_013887.1.
3D structure databases
ProteinModelPortal	D3S6J6.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADC70460; ADC70460; MFS40622_1790.
GeneID	8805665.
KEGG	mfs:MFS40622_1790.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000247372.
KO	K00800.
OMA	SNAGPFL.
Enzyme and pathway databases
BioCyc	MSP644281:GI4H-1845-MONOMER.
UniPathway	UPA00053; UER00089.
Family and domain databases
Gene3D	3.65.10.10. 2 hits.
HAMAP	MF_00210. EPSP_synth.
InterPro	IPR001986. Enolpyruvate_Tfrase_dom. IPR006264. EPSP_synthase. IPR023193. EPSP_synthase_CS. IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b. [Graphical view]
Pfam	PF00275. EPSP_synthase. 1 hit. [Graphical view]
PIRSF	PIRSF000505. EPSPS. 1 hit.
SUPFAM	SSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMs	TIGR01356. aroA. 1 hit.
PROSITE	PS00104. EPSP_SYNTHASE_1. 1 hit. PS00885. EPSP_SYNTHASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D3S6J6_METSF

Accession

Primary (citable) accession number: D3S6J6

Entry history

Integrated into UniProtKB/TrEMBL:	April 20, 2010
Last sequence update:	April 20, 2010
Last modified:	May 1, 2013
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)