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D3S572

- D3S572_METSF

UniProt

D3S572 - D3S572_METSF

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Protein
Tetrahydromethanopterin S-methyltransferase subunit F
Gene
mtrF, MFS40622_1309
Organism
Methanocaldococcus sp. (strain FS406-22)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step By similarity.UniRule annotation

Catalytic activityi

5-methyl-5,6,7,8-tetrahydromethanopterin + 2-mercaptoethanesulfonate = 5,6,7,8-tetrahydromethanopterin + 2-(methylthio)ethanesulfonate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. tetrahydromethanopterin S-methyltransferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. methanogenesis, from carbon dioxide Source: UniProtKB-UniPathway
  2. one-carbon metabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationImported, Transferase

Keywords - Biological processi

MethanogenesisUniRule annotation, One-carbon metabolismUniRule annotation

Enzyme and pathway databases

BioCyciMSP644281:GI4H-1335-MONOMER.
UniPathwayiUPA00640; UER00698.

Names & Taxonomyi

Protein namesi
Recommended name:
Tetrahydromethanopterin S-methyltransferase subunit FUniRule annotation (EC:2.1.1.86UniRule annotation)
Alternative name(s):
N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit F
Gene namesi
Name:mtrFUniRule annotation
Ordered Locus Names:MFS40622_1309Imported
OrganismiMethanocaldococcus sp. (strain FS406-22)Imported
Taxonomic identifieri644281 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
ProteomesiUP000002189: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei46 – 6621Helical; By similarityUniRule annotation
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membraneUniRule annotation, Membrane

Interactioni

Subunit structurei

The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH By similarity.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the MtrF family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

HOGENOMiHOG000229653.
KOiK00582.
OMAiPNISSIQ.

Family and domain databases

HAMAPiMF_01099. MtrF.
InterProiIPR011307. MeTrfase_F.
IPR013347. MeTrfase_F_su.
[Graphical view]
PfamiPF09472. MtrF. 1 hit.
[Graphical view]
PIRSFiPIRSF006523. MtrF. 1 hit.
TIGRFAMsiTIGR02507. MtrF. 1 hit.

Sequencei

Sequence statusi: Complete.

D3S572-1 [UniParc]FASTAAdd to Basket

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MGVEISNKPN VSSIESYVED LEYKVGLITR NRGLESGVES AGTKGLIIGA   50
VSALVLVGIP LAIYLLMR 68
Length:68
Mass (Da):7,205
Last modified:April 20, 2010 - v1
Checksum:iD975981E2338D1DC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001901 Genomic DNA. Translation: ADC69986.1.
RefSeqiWP_012980894.1. NC_013887.1.
YP_003458722.1. NC_013887.1.

Genome annotation databases

EnsemblBacteriaiADC69986; ADC69986; MFS40622_1309.
GeneIDi8805168.
KEGGimfs:MFS40622_1309.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001901 Genomic DNA. Translation: ADC69986.1 .
RefSeqi WP_012980894.1. NC_013887.1.
YP_003458722.1. NC_013887.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADC69986 ; ADC69986 ; MFS40622_1309 .
GeneIDi 8805168.
KEGGi mfs:MFS40622_1309.

Phylogenomic databases

HOGENOMi HOG000229653.
KOi K00582.
OMAi PNISSIQ.

Enzyme and pathway databases

UniPathwayi UPA00640 ; UER00698 .
BioCyci MSP644281:GI4H-1335-MONOMER.

Family and domain databases

HAMAPi MF_01099. MtrF.
InterProi IPR011307. MeTrfase_F.
IPR013347. MeTrfase_F_su.
[Graphical view ]
Pfami PF09472. MtrF. 1 hit.
[Graphical view ]
PIRSFi PIRSF006523. MtrF. 1 hit.
TIGRFAMsi TIGR02507. MtrF. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome of Methanocaldococcus sp. FS406-22."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Teshima H., Detter J.C., Han C., Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Sieprawska-Lupa M., Leigh J., Whitman W.B., Woyke T.
    Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: FS406-22Imported.

Entry informationi

Entry nameiD3S572_METSF
AccessioniPrimary (citable) accession number: D3S572
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: September 3, 2014
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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